Research graph
References from Avenanthramides in Obesity-Related Metabolic Dysfunction: Mechanisms, Evidence Attribution, and Translational Priorities. Local targets link to admitted publications; unresolved targets remain external evidence.
Obesity: Global Epidemiology and Pathogenesis
10.1038/s41574-019-0176-8 · 2019 · External reference
Obesity and Cardiovascular Disease: A Scientific Statement from the American Heart Association
2021 · External reference
Effect of Oat Supplementation Interventions on Cardiovascular Disease Risk Markers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
10.1007/s00394-021-02763-1 · 2022 · External reference
The Effect of Oat beta-Glucan on LDL-Cholesterol, Non-HDL-Cholesterol and ApoB for CVD Risk Reduction: A Systematic Review and Meta-Analysis of Randomised-Controlled Trials
10.1017/s000711451600341x · 2016 · External reference
The Progress of Nomenclature, Structure, Metabolism, and Bioactivities of Oat Novel Phytochemical: Avenanthramides
10.1021/acs.jafc.1c05704 · 2022 · External reference
Phenolic Amides (Avenanthramides) in Oats—An Update Review
10.1080/21655979.2024.2305029 · 2024 · External reference
Analysis of Avenanthramides in Oat Products and Estimation of Avenanthramide Intake in Humans
10.1016/j.foodchem.2018.01.138 · 2018 · External reference
Composition and Content of Phenolic Acids and Avenanthramides in Commercial Oat Products: Are Oats an Important Polyphenol Source for Consumers?
10.1016/j.fochx.2019.100047 · 2019 · External reference
Oat Phenolics: Avenanthramides, Novel Substituted N-Cinnamoylanthranilate Alkaloids from Oat Groats and Hulls
10.1021/jf00085a015 · 1989 · External reference
Avenanthramides in Oats (Avena sativa L.) and Structure–Antioxidant Activity Relationships
10.1021/jf020544f · 2003 · External reference
10.3390/plants10112485
10.3390/plants10112485 · External reference
Avenanthramides, Polyphenols from Oats, Inhibit IL-1β-Induced NF-κB Activation in Endothelial Cells
10.1016/j.freeradbiomed.2007.10.036 · 2008 · External reference
Avenanthramide, a Polyphenol from Oats, Inhibits Vascular Smooth Muscle Cell Proliferation and Enhances Nitric Oxide Production
10.1016/j.atherosclerosis.2005.07.027 · 2006 · External reference
Avenanthramides Ameliorate Insulin Resistance by Modulating Gluconeogenesis and Glycogen Synthesis in HepG2 Cells
10.1089/jmf.2024.k.0199 · 2025 · External reference
Oat Avenanthramide B Alleviates High-Fat Diet-Induced Obesity via Regulating Fatty Acid Metabolism Involved in Gut Bacteria and Fungi Remodeling
10.26599/fshw.2024.9250124 · 2025 · External reference
Consumption of Avenanthramides Extracted from Oats Reduces Weight Gain, Oxidative Stress, Inflammation and Regulates Intestinal Microflora in High Fat Diet-Induced Mice
10.1016/j.jff.2019.103774 · 2020 · External reference
Avenanthramides and Phenolic Acids from Oats Are Bioavailable and Act Synergistically with Vitamin C to Enhance Hamster and Human LDL Resistance to Oxidation
10.1093/jn/134.6.1459 · 2004 · External reference
Avenanthramides Are Bioavailable and Have Antioxidant Activity in Humans after Acute Consumption of an Enriched Mixture from Oats
10.1093/jn/137.6.1375 · 2007 · External reference
Absorption and Elimination of Oat Avenanthramides in Humans after Acute Consumption of Oat Cookies
10.1155/2017/2056705 · 2017 · External reference
Identification of Methylated Metabolites of Oat Avenanthramides in Human Plasma Using UHPLC QToF-MS
10.1080/09637486.2017.1371116 · 2018 · External reference
Excretion of Avenanthramides, Phenolic Acids and Their Major Metabolites Following Intake of Oat Bran
10.1002/mnfr.201700499 · 2018 · External reference
Avenanthramides and Avenacosides as Biomarkers of Oat Intake: A Pharmacokinetic Study of Solid and Liquid Oat Consumption under Single and Repeated Dose Conditions
10.1186/s12937-025-01204-7 · 2025 · External reference
Oat Avenanthramide-C (2c) Is Biotransformed by Mice and the Human Microbiota into Bioactive Metabolites
10.3945/jn.114.206508 · 2015 · External reference
Avenanthramide Metabotype from Whole-Grain Oat Intake Is Influenced by Faecalibacterium prausnitzii in Healthy Adults
10.1093/jn/nxab006 · 2021 · External reference
Biological Activities, Health Benefits, and Therapeutic Properties of Avenanthramides: From Skin Protection to Prevention and Treatment of Cerebrovascular Diseases
10.1155/2018/6015351 · 2018 · External reference
Mass Spectrometric Characterisation of Avenanthramides and Enhancing Their Production by Germination of Oat (Avena sativa)
10.1016/j.foodchem.2018.11.013 · 2019 · External reference
10.3390/foods11040560
10.3390/foods11040560 · External reference
Genotypic and Environmental Variations in Phenolic Acid and Avenanthramide Content of Canadian Oat (Avena sativa)
10.1016/j.foodchem.2022.132904 · 2022 · External reference
Identification and Quantification of Avenanthramides and Free and Bound Phenolic Acids in Eight Cultivars of Husked Oat (Avena sativa L.) from Finland
10.1021/acs.jafc.7b05726 · 2018 · External reference
Accurate Quantification and Antioxidant Evaluation of Avenanthramides in Oat Products Using Authentic Reference Standards
10.1016/j.fochx.2026.104183 · 2026 · External reference
Effects of Commercial Processing on Levels of Antioxidants in Oats (Avena sativa L.)
10.1021/jf011222z · 2002 · External reference
Variation in Oat Groats Due to Variety, Storage and Heat Treatment. I: Phenolic Compounds
10.1006/jcrs.1996.0058 · 1996 · External reference
Impact of Temperature and Humidity Conditions as Abiotic Stressors on the Phytochemical Fingerprint of Oat (Avena sativa L.) Sprouts
10.1016/j.foodchem.2023.138173 · 2024 · External reference
10.3390/molecules27196167
10.3390/molecules27196167 · External reference
Free and Bound Minor Polar Compounds in Oats: Different Extraction Methods and Analytical Determinations
10.1016/j.jcs.2011.05.005 · 2011 · External reference
Optimization of Parameters for Extraction of Avenanthramides from Oat (Avena sativa L.) Grain Using Response Surface Methodology (RSM)
2015 · External reference
Interaction of Oat Avenanthramides with Starch and Effects on In Vitro Avenanthramide Bioaccessibility and Starch Digestibility
10.1016/j.foodchem.2023.137770 · 2024 · External reference
Oat beta-Glucan: Physico-Chemical Characteristics in Relation to Its Blood-Glucose and Cholesterol-Lowering Properties
10.1017/s0007114514002256 · 2014 · External reference
Absorption Rates and Mechanisms of Avenanthramides in a Caco-2 Cell Model and Their Antioxidant Activity during Absorption
10.1021/acs.jafc.9b06576 · 2020 · External reference
Recommendations for Designing, Conducting, and Reporting Feeding Trials in Nutrition Research
10.1016/j.advnut.2024.100283 · 2024 · External reference
Avenanthramides Are Bioavailable and Accumulate in Hepatic, Cardiac, and Skeletal Muscle Tissue Following Oral Gavage in Rats
10.1021/jf2002427 · 2011 · External reference
Cholesterol-Lowering Effects of Oats Induced by Microbially Produced Phenolic Metabolites in Metabolic Syndrome: A Randomized Controlled Trial
10.1038/s41467-026-68303-9 · 2026 · External reference
Avenanthramide Supplementation Attenuates Exercise-Induced Inflammation in Postmenopausal Women
10.1186/1475-2891-13-21 · 2014 · External reference
Avenanthramide Supplementation Attenuates Eccentric Exercise-Inflicted Blood Inflammatory Markers in Women
10.1007/s00421-015-3244-3 · 2016 · External reference
Avenanthramide Supplementation Reduces Eccentric Exercise-Induced Inflammation in Young Men and Women
10.1186/s12970-020-00368-3 · 2020 · External reference
Oat Prevents Obesity and Abdominal Fat Distribution, and Improves Liver Function in Humans
10.1007/s11130-013-0336-2 · 2013 · External reference
10.3390/nu15040992
10.3390/nu15040992 · External reference
Oat Avenanthramide-C Alleviates DSS-Induced Colitis Through Regulating Intestinal Immune Activity and Gut Microbiota in Mice
10.1002/mnfr.70250 · 2025 · External reference
The Antiatherogenic Potential of Oat Phenolic Compounds
10.1016/j.atherosclerosis.2004.01.044 · 2004 · External reference
Mechanism by Which Avenanthramide-C, a Polyphenol of Oats, Blocks Cell Cycle Progression in Vascular Smooth Muscle Cells
10.1016/j.freeradbiomed.2006.04.020 · 2006 · External reference
Whole Grain Oats Improve Insulin Sensitivity and Plasma Cholesterol Profile and Modify Gut Microbiota Composition in C57BL/6J Mice
10.3945/jn.114.199778 · 2015 · External reference
The Separate Effects of Whole Oats and Isolated beta-Glucan on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
10.1016/j.clnesp.2022.12.019 · 2023 · External reference
10.3389/fnut.2021.722866
10.3389/fnut.2021.722866 · External reference
Effectiveness of Regular Oat beta-Glucan-Enriched Bread Compared with Whole-Grain Wheat Bread on Long-Term Glycemic Control in Adults at Risk of Type 2 Diabetes: A Randomized Controlled Trial
10.1016/j.ajcnut.2025.06.018 · 2025 · External reference
Comparison of Low-Gluten Diets Rich in Oats or Rice-A 6-Week Randomized Clinical Trial with Metabolically Challenged Volunteers
10.1002/mnfr.70076 · 2025 · External reference
Cholesterol-Lowering Effects of Oat beta-Glucan: A Meta-Analysis of Randomized Controlled Trials
10.3945/ajcn.114.086108 · 2014 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
Unresolved reference
External reference
Gluten Contamination in the Canadian Commercial Oat Supply
10.1080/19440049.2011.579626 · 2011 · External reference
Unresolved reference
External reference
Excretion of Avenanthramides, Phenolic Acids and Their Major Metabolites Following Intake of Oat Bran
10.1002/mnfr.201700499 · ExternalCitation · doi-reference
Comparison of Low-Gluten Diets Rich in Oats or Rice-A 6-Week Randomized Clinical Trial with Metabolically Challenged Volunteers
10.1002/mnfr.70076 · ExternalCitation · doi-reference
Oat Avenanthramide-C Alleviates DSS-Induced Colitis Through Regulating Intestinal Immune Activity and Gut Microbiota in Mice
10.1002/mnfr.70250 · ExternalCitation · doi-reference
Variation in Oat Groats Due to Variety, Storage and Heat Treatment. I: Phenolic Compounds
10.1006/jcrs.1996.0058 · ExternalCitation · doi-reference
Effect of Oat Supplementation Interventions on Cardiovascular Disease Risk Markers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
10.1007/s00394-021-02763-1 · ExternalCitation · doi-reference
Avenanthramide Supplementation Attenuates Eccentric Exercise-Inflicted Blood Inflammatory Markers in Women
10.1007/s00421-015-3244-3 · ExternalCitation · doi-reference
Oat Prevents Obesity and Abdominal Fat Distribution, and Improves Liver Function in Humans
10.1007/s11130-013-0336-2 · ExternalCitation · doi-reference
Recommendations for Designing, Conducting, and Reporting Feeding Trials in Nutrition Research
10.1016/j.advnut.2024.100283 · ExternalCitation · doi-reference
Effectiveness of Regular Oat beta-Glucan-Enriched Bread Compared with Whole-Grain Wheat Bread on Long-Term Glycemic Control in Adults at Risk of Type 2 Diabetes: A Randomized Controlled Trial
10.1016/j.ajcnut.2025.06.018 · ExternalCitation · doi-reference
The Antiatherogenic Potential of Oat Phenolic Compounds
10.1016/j.atherosclerosis.2004.01.044 · ExternalCitation · doi-reference
Avenanthramide, a Polyphenol from Oats, Inhibits Vascular Smooth Muscle Cell Proliferation and Enhances Nitric Oxide Production
10.1016/j.atherosclerosis.2005.07.027 · ExternalCitation · doi-reference
The Separate Effects of Whole Oats and Isolated beta-Glucan on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
10.1016/j.clnesp.2022.12.019 · ExternalCitation · doi-reference
Composition and Content of Phenolic Acids and Avenanthramides in Commercial Oat Products: Are Oats an Important Polyphenol Source for Consumers?
10.1016/j.fochx.2019.100047 · ExternalCitation · doi-reference
Accurate Quantification and Antioxidant Evaluation of Avenanthramides in Oat Products Using Authentic Reference Standards
10.1016/j.fochx.2026.104183 · ExternalCitation · doi-reference
Analysis of Avenanthramides in Oat Products and Estimation of Avenanthramide Intake in Humans
10.1016/j.foodchem.2018.01.138 · ExternalCitation · doi-reference
Mass Spectrometric Characterisation of Avenanthramides and Enhancing Their Production by Germination of Oat (Avena sativa)
10.1016/j.foodchem.2018.11.013 · ExternalCitation · doi-reference
Genotypic and Environmental Variations in Phenolic Acid and Avenanthramide Content of Canadian Oat (Avena sativa)
10.1016/j.foodchem.2022.132904 · ExternalCitation · doi-reference
Interaction of Oat Avenanthramides with Starch and Effects on In Vitro Avenanthramide Bioaccessibility and Starch Digestibility
10.1016/j.foodchem.2023.137770 · ExternalCitation · doi-reference
Impact of Temperature and Humidity Conditions as Abiotic Stressors on the Phytochemical Fingerprint of Oat (Avena sativa L.) Sprouts
10.1016/j.foodchem.2023.138173 · ExternalCitation · doi-reference
Mechanism by Which Avenanthramide-C, a Polyphenol of Oats, Blocks Cell Cycle Progression in Vascular Smooth Muscle Cells
10.1016/j.freeradbiomed.2006.04.020 · ExternalCitation · doi-reference
Avenanthramides, Polyphenols from Oats, Inhibit IL-1β-Induced NF-κB Activation in Endothelial Cells
10.1016/j.freeradbiomed.2007.10.036 · ExternalCitation · doi-reference
Free and Bound Minor Polar Compounds in Oats: Different Extraction Methods and Analytical Determinations
10.1016/j.jcs.2011.05.005 · ExternalCitation · doi-reference
Consumption of Avenanthramides Extracted from Oats Reduces Weight Gain, Oxidative Stress, Inflammation and Regulates Intestinal Microflora in High Fat Diet-Induced Mice
10.1016/j.jff.2019.103774 · ExternalCitation · doi-reference
Oat beta-Glucan: Physico-Chemical Characteristics in Relation to Its Blood-Glucose and Cholesterol-Lowering Properties
10.1017/s0007114514002256 · ExternalCitation · doi-reference
The Effect of Oat beta-Glucan on LDL-Cholesterol, Non-HDL-Cholesterol and ApoB for CVD Risk Reduction: A Systematic Review and Meta-Analysis of Randomised-Controlled Trials
10.1017/s000711451600341x · ExternalCitation · doi-reference
The Progress of Nomenclature, Structure, Metabolism, and Bioactivities of Oat Novel Phytochemical: Avenanthramides
10.1021/acs.jafc.1c05704 · ExternalCitation · doi-reference
Identification and Quantification of Avenanthramides and Free and Bound Phenolic Acids in Eight Cultivars of Husked Oat (Avena sativa L.) from Finland
10.1021/acs.jafc.7b05726 · ExternalCitation · doi-reference
Absorption Rates and Mechanisms of Avenanthramides in a Caco-2 Cell Model and Their Antioxidant Activity during Absorption
10.1021/acs.jafc.9b06576 · ExternalCitation · doi-reference
Oat Phenolics: Avenanthramides, Novel Substituted N-Cinnamoylanthranilate Alkaloids from Oat Groats and Hulls
10.1021/jf00085a015 · ExternalCitation · doi-reference
Effects of Commercial Processing on Levels of Antioxidants in Oats (Avena sativa L.)
10.1021/jf011222z · ExternalCitation · doi-reference
Avenanthramides in Oats (Avena sativa L.) and Structure–Antioxidant Activity Relationships
10.1021/jf020544f · ExternalCitation · doi-reference
Avenanthramides Are Bioavailable and Accumulate in Hepatic, Cardiac, and Skeletal Muscle Tissue Following Oral Gavage in Rats
10.1021/jf2002427 · ExternalCitation · doi-reference
Cholesterol-Lowering Effects of Oats Induced by Microbially Produced Phenolic Metabolites in Metabolic Syndrome: A Randomized Controlled Trial
10.1038/s41467-026-68303-9 · ExternalCitation · doi-reference
Obesity: Global Epidemiology and Pathogenesis
10.1038/s41574-019-0176-8 · ExternalCitation · doi-reference
Identification of Methylated Metabolites of Oat Avenanthramides in Human Plasma Using UHPLC QToF-MS
10.1080/09637486.2017.1371116 · ExternalCitation · doi-reference
Gluten Contamination in the Canadian Commercial Oat Supply
10.1080/19440049.2011.579626 · ExternalCitation · doi-reference
Phenolic Amides (Avenanthramides) in Oats—An Update Review
10.1080/21655979.2024.2305029 · ExternalCitation · doi-reference
Avenanthramides Ameliorate Insulin Resistance by Modulating Gluconeogenesis and Glycogen Synthesis in HepG2 Cells
10.1089/jmf.2024.k.0199 · ExternalCitation · doi-reference
Avenanthramides and Phenolic Acids from Oats Are Bioavailable and Act Synergistically with Vitamin C to Enhance Hamster and Human LDL Resistance to Oxidation
10.1093/jn/134.6.1459 · ExternalCitation · doi-reference
Avenanthramides Are Bioavailable and Have Antioxidant Activity in Humans after Acute Consumption of an Enriched Mixture from Oats
10.1093/jn/137.6.1375 · ExternalCitation · doi-reference
Avenanthramide Metabotype from Whole-Grain Oat Intake Is Influenced by Faecalibacterium prausnitzii in Healthy Adults
10.1093/jn/nxab006 · ExternalCitation · doi-reference
Absorption and Elimination of Oat Avenanthramides in Humans after Acute Consumption of Oat Cookies
10.1155/2017/2056705 · ExternalCitation · doi-reference
Biological Activities, Health Benefits, and Therapeutic Properties of Avenanthramides: From Skin Protection to Prevention and Treatment of Cerebrovascular Diseases
10.1155/2018/6015351 · ExternalCitation · doi-reference
Avenanthramide Supplementation Attenuates Exercise-Induced Inflammation in Postmenopausal Women
10.1186/1475-2891-13-21 · ExternalCitation · doi-reference
Avenanthramides and Avenacosides as Biomarkers of Oat Intake: A Pharmacokinetic Study of Solid and Liquid Oat Consumption under Single and Repeated Dose Conditions
10.1186/s12937-025-01204-7 · ExternalCitation · doi-reference
Avenanthramide Supplementation Reduces Eccentric Exercise-Induced Inflammation in Young Men and Women
10.1186/s12970-020-00368-3 · ExternalCitation · doi-reference
Oat Avenanthramide B Alleviates High-Fat Diet-Induced Obesity via Regulating Fatty Acid Metabolism Involved in Gut Bacteria and Fungi Remodeling
10.26599/fshw.2024.9250124 · ExternalCitation · doi-reference
10.3389/fnut.2021.722866
10.3389/fnut.2021.722866 · ExternalCitation · doi-reference
10.3390/foods11040560
10.3390/foods11040560 · ExternalCitation · doi-reference
10.3390/molecules27196167
10.3390/molecules27196167 · ExternalCitation · doi-reference
10.3390/nu15040992
10.3390/nu15040992 · ExternalCitation · doi-reference
10.3390/plants10112485
10.3390/plants10112485 · ExternalCitation · doi-reference
Cholesterol-Lowering Effects of Oat beta-Glucan: A Meta-Analysis of Randomized Controlled Trials
10.3945/ajcn.114.086108 · ExternalCitation · doi-reference
Whole Grain Oats Improve Insulin Sensitivity and Plasma Cholesterol Profile and Modify Gut Microbiota Composition in C57BL/6J Mice
10.3945/jn.114.199778 · ExternalCitation · doi-reference
Oat Avenanthramide-C (2c) Is Biotransformed by Mice and the Human Microbiota into Bioactive Metabolites
10.3945/jn.114.206508 · ExternalCitation · doi-reference
