Research graph
References from Efficient Cryopreservation of Human Midbrain Organoids Using Conventional DMSO Protocols with Ice Recrystallization Inhibitors. Local targets link to admitted publications; unresolved targets remain external evidence.
Human Organoids: Model Systems for Human Biology and Medicine
10.1038/s41580-020-0259-3 · 2020 · External reference
Cerebral Organoids Model Human Brain Development and Microcephaly
10.1038/nature12517 · 2013 · External reference
Cell Diversity and Network Dynamics in Photosensitive Human Brain Organoids
10.1038/nature22047 · 2017 · External reference
Generation of Cerebral Organoids from Human Pluripotent Stem Cells
10.1038/nprot.2014.158 · 2014 · External reference
Midbrain Organoids-Development and Applications in Parkinson’s Disease
10.1093/oons/kvad009 · 2023 · External reference
Advances, Challenges, and Opportunities of Human Midbrain Organoids for Modelling of the Dopaminergic System
10.1038/s44318-025-00494-1 · 2025 · External reference
Modeling Parkinson’s Disease in Midbrain-like Organoids
10.1038/s41531-019-0078-4 · 2019 · External reference
Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells
10.1016/j.stemcr.2017.03.010 · 2017 · External reference
Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons
10.1016/j.stem.2016.07.005 · 2016 · External reference
Human Midbrain Organoids: A Powerful Tool for Advanced Parkinson’s Disease Modeling and Therapy Exploration
10.1038/s41531-024-00799-8 · 2024 · External reference
Long-Term Maturation of Human Cortical Organoids Matches Key Early Postnatal Transitions
10.1038/s41593-021-00802-y · 2021 · External reference
Microfabricated Disk Technology: Rapid Scale up in Midbrain Organoid Generation
10.1016/j.ymeth.2021.07.008 · 2022 · External reference
Production of Highly Uniform Midbrain Organoids from Human Pluripotent Stem Cells
10.1155/2023/3320211 · 2023 · External reference
From Organoid Culture to Manufacturing: Technologies for Reproducible and Scalable Organoid Production
10.1038/s44385-025-00054-6 · 2026 · External reference
Cryopreservation of Human Kidney Organoids
10.1007/s00018-024-05352-7 · 2024 · External reference
Reproducible Generation of Human Midbrain Organoids for in Vitro Modeling of Parkinson’s Disease
10.1016/j.scr.2020.101870 · 2020 · External reference
A Simple and Efficient Cryopreservation Method for Mouse Small Intestinal and Colon Organoids for Regenerative Medicine
10.1016/j.bbrc.2021.12.021 · 2022 · External reference
A Method for Cryogenic Preservation of Human Biopsy Specimens and Subsequent Organoid Culture
10.1016/j.jcmgh.2018.04.008 · 2018 · External reference
Establishment and Culture of Human Intestinal Organoids Derived from Adult Stem Cells
10.1002/cpim.106 · 2020 · External reference
Cryopreservation of Hepatocyte Organoid-Derived Cells Generated from Human iPS Cells
10.1248/bpb.b25-00276 · 2025 · External reference
Prediction of Acute Hepatotoxicity With Human Pluripotent Stem Cell-Derived Hepatic Organoids
10.1002/cpz1.1015 · 2024 · External reference
Human Induced Pluripotent Stem Cell Derived Kidney Organoids as a Model System for Studying Cryopreservation
10.1016/j.cryobiol.2021.08.006 · 2021 · External reference
A Pan-Cancer Organoid Platform for Precision Medicine
10.1016/j.celrep.2021.109429 · 2021 · External reference
Cryopreservation of Viable Human Tissues: Renewable Resource for Viable Tissue, Cell Lines, and Organoid Development
10.1089/bio.2019.0062 · 2020 · External reference
Effective Cryopreservation of Human Brain Tissue and Neural Organoids
10.1016/j.crmeth.2024.100777 · 2024 · External reference
10.1101/2025.04.08.647634
10.1101/2025.04.08.647634 · External reference
Chemical Approaches to Cryopreservation
10.1038/s41570-022-00407-4 · 2022 · External reference
Targeted Development and Optimization of Small-Molecule Ice Recrystallization Inhibitors (IRIs) for the Cryopreservation of Biological Systems
10.54680/fr24210110112 · 2024 · External reference
Enhanced Non-Vitreous Cryopreservation of Immortalized and Primary Cells by Ice-Growth Inhibiting Polymers
10.1039/c6bm00129g · 2016 · External reference
The Effect of Dimethylsulfoxide on the Water Transport Response of Rat Hepatocytes During Freezing
10.1115/1.2834744 · 1998 · External reference
Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservation
10.1021/jacsau.3c00056 · 2023 · External reference
Improved Cryopreservation of Human Induced Pluripotent Stem Cell (iPSC) and iPSC-Derived Neurons Using Ice-Recrystallization Inhibitors
10.1093/stmcls/sxad059 · 2023 · External reference
Small-Molecule Ice Recrystallization Inhibitors Improve the Post-Thaw Function of Hematopoietic Stem and Progenitor Cells
10.1021/acsomega.6b00178 · 2016 · External reference
Quantitative Analysis of the Efficacy and Potency of Novel Small Molecule Ice Recrystallization Inhibitors
10.1021/acs.cgd.5b00995 · 2015 · External reference
10.2139/ssrn.3804839
10.2139/ssrn.3804839 · External reference
Flow Cytometry Controls, Instrument Setup, and the Determination of Positivity
10.1002/cyto.a.20333 · 2006 · External reference
10.1101/2023.08.30.554628
10.1101/2023.08.30.554628 · External reference
Electrophysiological and Morphological Characterization of Single Neurons in Intact Human Brain Organoids
10.1016/j.jneumeth.2023.109898 · 2023 · External reference
Unresolved reference
External reference
Establishment and Culture of Human Intestinal Organoids Derived from Adult Stem Cells
10.1002/cpim.106 · ExternalCitation · doi-reference
Prediction of Acute Hepatotoxicity With Human Pluripotent Stem Cell-Derived Hepatic Organoids
10.1002/cpz1.1015 · ExternalCitation · doi-reference
Flow Cytometry Controls, Instrument Setup, and the Determination of Positivity
10.1002/cyto.a.20333 · ExternalCitation · doi-reference
Cryopreservation of Human Kidney Organoids
10.1007/s00018-024-05352-7 · ExternalCitation · doi-reference
A Simple and Efficient Cryopreservation Method for Mouse Small Intestinal and Colon Organoids for Regenerative Medicine
10.1016/j.bbrc.2021.12.021 · ExternalCitation · doi-reference
A Pan-Cancer Organoid Platform for Precision Medicine
10.1016/j.celrep.2021.109429 · ExternalCitation · doi-reference
Effective Cryopreservation of Human Brain Tissue and Neural Organoids
10.1016/j.crmeth.2024.100777 · ExternalCitation · doi-reference
Human Induced Pluripotent Stem Cell Derived Kidney Organoids as a Model System for Studying Cryopreservation
10.1016/j.cryobiol.2021.08.006 · ExternalCitation · doi-reference
A Method for Cryogenic Preservation of Human Biopsy Specimens and Subsequent Organoid Culture
10.1016/j.jcmgh.2018.04.008 · ExternalCitation · doi-reference
Electrophysiological and Morphological Characterization of Single Neurons in Intact Human Brain Organoids
10.1016/j.jneumeth.2023.109898 · ExternalCitation · doi-reference
Reproducible Generation of Human Midbrain Organoids for in Vitro Modeling of Parkinson’s Disease
10.1016/j.scr.2020.101870 · ExternalCitation · doi-reference
Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons
10.1016/j.stem.2016.07.005 · ExternalCitation · doi-reference
Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells
10.1016/j.stemcr.2017.03.010 · ExternalCitation · doi-reference
Microfabricated Disk Technology: Rapid Scale up in Midbrain Organoid Generation
10.1016/j.ymeth.2021.07.008 · ExternalCitation · doi-reference
Quantitative Analysis of the Efficacy and Potency of Novel Small Molecule Ice Recrystallization Inhibitors
10.1021/acs.cgd.5b00995 · ExternalCitation · doi-reference
Small-Molecule Ice Recrystallization Inhibitors Improve the Post-Thaw Function of Hematopoietic Stem and Progenitor Cells
10.1021/acsomega.6b00178 · ExternalCitation · doi-reference
Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservation
10.1021/jacsau.3c00056 · ExternalCitation · doi-reference
Cerebral Organoids Model Human Brain Development and Microcephaly
10.1038/nature12517 · ExternalCitation · doi-reference
Cell Diversity and Network Dynamics in Photosensitive Human Brain Organoids
10.1038/nature22047 · ExternalCitation · doi-reference
Generation of Cerebral Organoids from Human Pluripotent Stem Cells
10.1038/nprot.2014.158 · ExternalCitation · doi-reference
Modeling Parkinson’s Disease in Midbrain-like Organoids
10.1038/s41531-019-0078-4 · ExternalCitation · doi-reference
Human Midbrain Organoids: A Powerful Tool for Advanced Parkinson’s Disease Modeling and Therapy Exploration
10.1038/s41531-024-00799-8 · ExternalCitation · doi-reference
Chemical Approaches to Cryopreservation
10.1038/s41570-022-00407-4 · ExternalCitation · doi-reference
Human Organoids: Model Systems for Human Biology and Medicine
10.1038/s41580-020-0259-3 · ExternalCitation · doi-reference
Long-Term Maturation of Human Cortical Organoids Matches Key Early Postnatal Transitions
10.1038/s41593-021-00802-y · ExternalCitation · doi-reference
Advances, Challenges, and Opportunities of Human Midbrain Organoids for Modelling of the Dopaminergic System
10.1038/s44318-025-00494-1 · ExternalCitation · doi-reference
From Organoid Culture to Manufacturing: Technologies for Reproducible and Scalable Organoid Production
10.1038/s44385-025-00054-6 · ExternalCitation · doi-reference
Enhanced Non-Vitreous Cryopreservation of Immortalized and Primary Cells by Ice-Growth Inhibiting Polymers
10.1039/c6bm00129g · ExternalCitation · doi-reference
Cryopreservation of Viable Human Tissues: Renewable Resource for Viable Tissue, Cell Lines, and Organoid Development
10.1089/bio.2019.0062 · ExternalCitation · doi-reference
Midbrain Organoids-Development and Applications in Parkinson’s Disease
10.1093/oons/kvad009 · ExternalCitation · doi-reference
Improved Cryopreservation of Human Induced Pluripotent Stem Cell (iPSC) and iPSC-Derived Neurons Using Ice-Recrystallization Inhibitors
10.1093/stmcls/sxad059 · ExternalCitation · doi-reference
10.1101/2023.08.30.554628
10.1101/2023.08.30.554628 · ExternalCitation · doi-reference
10.1101/2025.04.08.647634
10.1101/2025.04.08.647634 · ExternalCitation · doi-reference
The Effect of Dimethylsulfoxide on the Water Transport Response of Rat Hepatocytes During Freezing
10.1115/1.2834744 · ExternalCitation · doi-reference
Production of Highly Uniform Midbrain Organoids from Human Pluripotent Stem Cells
10.1155/2023/3320211 · ExternalCitation · doi-reference
Cryopreservation of Hepatocyte Organoid-Derived Cells Generated from Human iPS Cells
10.1248/bpb.b25-00276 · ExternalCitation · doi-reference
10.2139/ssrn.3804839
10.2139/ssrn.3804839 · ExternalCitation · doi-reference
Targeted Development and Optimization of Small-Molecule Ice Recrystallization Inhibitors (IRIs) for the Cryopreservation of Biological Systems
10.54680/fr24210110112 · ExternalCitation · doi-reference
