Research graph
References from Design, Synthesis and Antihyperglycemic/Antilipidemic Activities of Quinoline-thiazolidine-2,4-dione Hybrid. Local targets link to admitted publications; unresolved targets remain external evidence.
Diabetes: A Defining Disease of the 21st Century
10.1016/s0140-6736(23)01296-5 · 2023 · External reference
History of Diabetes Mellitus
10.15537/1658-3175.1664 · 2002 · External reference
Unresolved reference
External reference
10.3390/ph18071023
10.3390/ph18071023 · External reference
Classification and Diagnosis of Diabetes: Standards of Care
2023 · External reference
10.2337/dc25-s016
10.2337/dc25-s016 · External reference
10.3390/ijms21176275
10.3390/ijms21176275 · External reference
Obesity and Diabetes
10.1016/j.diabres.2023.110773 · 2023 · External reference
β Cell Function and Plasma Insulin Clearance in People with Obesity and Different Glycemic Status
10.1172/jci154068 · 2022 · External reference
Concomitant Therapy with Pioglitazone and Insulin for the Treatment of Type 2 Diabetes
10.2147/vhrm.s5838 · 2010 · External reference
Thiazolidine-2,4-Diones: Progress towards Multifarious Applications
10.1016/j.bmc.2013.01.029 · 2013 · External reference
Unresolved reference
External reference
10.3390/ph12040152
10.3390/ph12040152 · External reference
Antidiabetic Drug Use Trends in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease: A Cross-Sectional Analysis of NHANES
10.1111/1753-0407.13003 · 2020 · External reference
The Peroxisome Proliferator-Activated Receptor: A Family of Nuclear Receptors Role in Various Diseases
10.4103/2231-4040.90879 · 2011 · External reference
Revisiting PPARγ as a Target for the Treatment of Metabolic Disorders
10.5483/bmbrep.2014.47.11.174 · 2014 · External reference
Thiazolidinediones and Liver Toxicity
2001 · External reference
Genotoxicity in Rats Treated with the Antidiabetic Agent, Rosiglitazone
10.1002/em.20261 · 2006 · External reference
Quinoline-Based Schiff Bases as Possible Antidiabetic Agents: Pharmacophore Modeling, 3D QSAR, Docking, and Molecular Dynamics Simulations
10.1039/d4md00344f · 2024 · External reference
Synthesis and antimicrobial activity of 2, 4-dioxothiazolidine-5-acetic acid amides
10.1007/s11094-006-0115-6 · 2006 · External reference
10.3390/molecules25245944
10.3390/molecules25245944 · External reference
10.3389/fphar.2017.00798
10.3389/fphar.2017.00798 · External reference
Association of Apolipoprotein AV with mRNA Expression of IL-6 and NF-κB Genes in Type 2 Diabetes with Hypertriglyceridemia: A Possible Link with Inflammation
10.1007/s13410-018-0709-z · 2019 · External reference
β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment
10.1210/jc.2014-1425 · 2014 · External reference
The Nature and Characteristics of Hypertriglyceridemia in a Large Cohort with Type 2 Diabetes
10.1016/j.jdiacomp.2022.108387 · 2023 · External reference
Mechanisms Linking Hypertriglyceridemia to Acute Pancreatitis
10.1111/apha.13916 · 2023 · External reference
10.3390/antiox12030595
10.3390/antiox12030595 · External reference
Antiglycation Activity of Quinoline Derivatives—A New Therapeutic Class for the Management of Type 2 Diabetes Complications
10.2174/1573406410666140526151254 · 2015 · External reference
Pyrano[3,2-c]quinoline Derivatives as New Class of α-Glucosidase Inhibitors to Treat Type 2 Diabetes: Synthesis, In Vitro Biological Evaluation and Kinetic Study
10.2174/1573406414666180528110104 · 2019 · External reference
Synthesis of New Hybrid Indolyl-Pyridines with Sulfonamide Moiety in the Presence of Fe3O4@SiO2@(CH2)3-Urea-Quinolinium Trifluoroacetate via a Cooperative Vinylogous Anomeric-Based Oxidation
10.1007/s13738-023-02794-x · 2023 · External reference
Synthesis of Quinoline Derivatives as Diabetic II Inhibitors and Molecular Docking Studies
10.1016/j.bmc.2019.07.035 · 2019 · External reference
10.3390/foods10081939
10.3390/foods10081939 · External reference
10.3389/fphar.2020.00185
10.3389/fphar.2020.00185 · External reference
Antifungal Exploration of Quinoline Derivatives against Phytopathogenic Fungi Inspired by Quinine Alkaloids
10.1021/acs.jafc.1c05677 · 2021 · External reference
10.3390/cells10092263
10.3390/cells10092263 · External reference
10-Iodo-11H-Indolo[3,2-c]quinoline-6-Carboxylic Acids Are Selective Inhibitors of DYRK1A
10.1021/jm501994d · 2015 · External reference
10.3390/ijms22169083
10.3390/ijms22169083 · External reference
Design, Synthesis and Antiplasmodial Activity of Novel Imidazole Derivatives Based on 7-Chloro-4-Aminoquinoline
10.1016/j.bioorg.2018.06.012 · 2018 · External reference
Molecular Docking Using Chimera and Autodock Vina Software for Nonbioinformaticians
10.2196/14232 · 2020 · External reference
Simplified Protocol for Production of Persistent Hyperglycemic Zebrafish Model for Type II Diabetes Mellitus Studying
10.21608/ejabf.2024.354861 · 2024 · External reference
10.3390/ph15030341
10.3390/ph15030341 · External reference
Nile Crab Potamonautes niloticus Shell Extract: Chromatographic and Molecular Elucidation of Potent Antioxidant and Anti-Inflammatory Capabilities
10.1016/j.bioorg.2022.106023 · 2022 · External reference
Oral cortisol and dexamethasone intake: Differential physiology and transcriptional responses in the marine juvenile Sparus aurata
10.1016/j.ygcen.2023.114371 · 2023 · External reference
Tryptophan-supplemented diet modulates the metabolic response of European seabass (Dicentrarchus labrax) juveniles reared under space-confined conditions and submitted to acute inflammation
10.1007/s10695-024-01427-1 · 2025 · External reference
Genotoxicity in Rats Treated with the Antidiabetic Agent, Rosiglitazone
10.1002/em.20261 · ExternalCitation · doi-reference
Tryptophan-supplemented diet modulates the metabolic response of European seabass (Dicentrarchus labrax) juveniles reared under space-confined conditions and submitted to acute inflammation
10.1007/s10695-024-01427-1 · ExternalCitation · doi-reference
Synthesis and antimicrobial activity of 2, 4-dioxothiazolidine-5-acetic acid amides
10.1007/s11094-006-0115-6 · ExternalCitation · doi-reference
Association of Apolipoprotein AV with mRNA Expression of IL-6 and NF-κB Genes in Type 2 Diabetes with Hypertriglyceridemia: A Possible Link with Inflammation
10.1007/s13410-018-0709-z · ExternalCitation · doi-reference
Synthesis of New Hybrid Indolyl-Pyridines with Sulfonamide Moiety in the Presence of Fe3O4@SiO2@(CH2)3-Urea-Quinolinium Trifluoroacetate via a Cooperative Vinylogous Anomeric-Based Oxidation
10.1007/s13738-023-02794-x · ExternalCitation · doi-reference
Design, Synthesis and Antiplasmodial Activity of Novel Imidazole Derivatives Based on 7-Chloro-4-Aminoquinoline
10.1016/j.bioorg.2018.06.012 · ExternalCitation · doi-reference
Nile Crab Potamonautes niloticus Shell Extract: Chromatographic and Molecular Elucidation of Potent Antioxidant and Anti-Inflammatory Capabilities
10.1016/j.bioorg.2022.106023 · ExternalCitation · doi-reference
Thiazolidine-2,4-Diones: Progress towards Multifarious Applications
10.1016/j.bmc.2013.01.029 · ExternalCitation · doi-reference
Synthesis of Quinoline Derivatives as Diabetic II Inhibitors and Molecular Docking Studies
10.1016/j.bmc.2019.07.035 · ExternalCitation · doi-reference
Obesity and Diabetes
10.1016/j.diabres.2023.110773 · ExternalCitation · doi-reference
The Nature and Characteristics of Hypertriglyceridemia in a Large Cohort with Type 2 Diabetes
10.1016/j.jdiacomp.2022.108387 · ExternalCitation · doi-reference
Oral cortisol and dexamethasone intake: Differential physiology and transcriptional responses in the marine juvenile Sparus aurata
10.1016/j.ygcen.2023.114371 · ExternalCitation · doi-reference
Diabetes: A Defining Disease of the 21st Century
10.1016/s0140-6736(23)01296-5 · ExternalCitation · doi-reference
Antifungal Exploration of Quinoline Derivatives against Phytopathogenic Fungi Inspired by Quinine Alkaloids
10.1021/acs.jafc.1c05677 · ExternalCitation · doi-reference
10-Iodo-11H-Indolo[3,2-c]quinoline-6-Carboxylic Acids Are Selective Inhibitors of DYRK1A
10.1021/jm501994d · ExternalCitation · doi-reference
Quinoline-Based Schiff Bases as Possible Antidiabetic Agents: Pharmacophore Modeling, 3D QSAR, Docking, and Molecular Dynamics Simulations
10.1039/d4md00344f · ExternalCitation · doi-reference
Antidiabetic Drug Use Trends in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease: A Cross-Sectional Analysis of NHANES
10.1111/1753-0407.13003 · ExternalCitation · doi-reference
Mechanisms Linking Hypertriglyceridemia to Acute Pancreatitis
10.1111/apha.13916 · ExternalCitation · doi-reference
β Cell Function and Plasma Insulin Clearance in People with Obesity and Different Glycemic Status
10.1172/jci154068 · ExternalCitation · doi-reference
β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment
10.1210/jc.2014-1425 · ExternalCitation · doi-reference
History of Diabetes Mellitus
10.15537/1658-3175.1664 · ExternalCitation · doi-reference
Concomitant Therapy with Pioglitazone and Insulin for the Treatment of Type 2 Diabetes
10.2147/vhrm.s5838 · ExternalCitation · doi-reference
Simplified Protocol for Production of Persistent Hyperglycemic Zebrafish Model for Type II Diabetes Mellitus Studying
10.21608/ejabf.2024.354861 · ExternalCitation · doi-reference
Antiglycation Activity of Quinoline Derivatives—A New Therapeutic Class for the Management of Type 2 Diabetes Complications
10.2174/1573406410666140526151254 · ExternalCitation · doi-reference
Pyrano[3,2-c]quinoline Derivatives as New Class of α-Glucosidase Inhibitors to Treat Type 2 Diabetes: Synthesis, In Vitro Biological Evaluation and Kinetic Study
10.2174/1573406414666180528110104 · ExternalCitation · doi-reference
Molecular Docking Using Chimera and Autodock Vina Software for Nonbioinformaticians
10.2196/14232 · ExternalCitation · doi-reference
10.2337/dc25-s016
10.2337/dc25-s016 · ExternalCitation · doi-reference
10.3389/fphar.2017.00798
10.3389/fphar.2017.00798 · ExternalCitation · doi-reference
10.3389/fphar.2020.00185
10.3389/fphar.2020.00185 · ExternalCitation · doi-reference
10.3390/antiox12030595
10.3390/antiox12030595 · ExternalCitation · doi-reference
10.3390/cells10092263
10.3390/cells10092263 · ExternalCitation · doi-reference
10.3390/foods10081939
10.3390/foods10081939 · ExternalCitation · doi-reference
10.3390/ijms21176275
10.3390/ijms21176275 · ExternalCitation · doi-reference
10.3390/ijms22169083
10.3390/ijms22169083 · ExternalCitation · doi-reference
10.3390/molecules25245944
10.3390/molecules25245944 · ExternalCitation · doi-reference
10.3390/ph12040152
10.3390/ph12040152 · ExternalCitation · doi-reference
10.3390/ph15030341
10.3390/ph15030341 · ExternalCitation · doi-reference
10.3390/ph18071023
10.3390/ph18071023 · ExternalCitation · doi-reference
The Peroxisome Proliferator-Activated Receptor: A Family of Nuclear Receptors Role in Various Diseases
10.4103/2231-4040.90879 · ExternalCitation · doi-reference
Revisiting PPARγ as a Target for the Treatment of Metabolic Disorders
10.5483/bmbrep.2014.47.11.174 · ExternalCitation · doi-reference