Research graph
References from The Monitoring Paradox: Frontal Electroencephalography Reveals Profound Cortical Depression Despite Cardiovascular Stability in Dogs Undergoing Tibial Plateau Leveling Osteotomy with Isoflurane Anesthesia and Multimodal Analgesic Protocols. Local targets link to admitted publications; unresolved targets remain external evidence.
General anesthesia, sleep, and coma
10.1056/nejmra0808281 · 2010 · External reference
Prevention of Intraoperative Awareness in a High-Risk Surgical Population
10.1056/nejmoa1100403 · 2011 · External reference
Mechanisms of action of inhaled anesthetics
10.1056/nejmra021261 · 2003 · External reference
The aging brain and anesthesia
10.1097/aco.0b013e328362d183 · 2013 · External reference
Towards a comprehensive understanding of anesthetic mechanisms of action: A decade of discovery
2019 · External reference
10.3389/fncir.2017.00044
10.3389/fncir.2017.00044 · External reference
Understanding the effects of general anesthetics on cortical network activity using ex vivo preparations
10.1097/aln.0000000000002554 · 2019 · External reference
Cortico-thalamic circuit model for bottom up and top down mechanisms in general anesthesia involving the reticular activating system
2019 · External reference
Broadly applicable risk stratification system for predicting duration of hospitalization and mortality
10.1097/aln.0b013e3181f79a8d · 2010 · External reference
Hospital stay and mortality are increased in patients having a “triple low” of low blood pressure, low bispectral index, and low minimum alveolar concentration of volatile anesthesia
10.1097/aln.0b013e31825683dc · 2012 · External reference
Is “triple low” of low blood pressure, low bispectral index, and low minimum alveolar concentration of volatile anesthesia an independent predictor for postoperative mortality?
10.1097/aln.0b013e318278caf9 · 2013 · External reference
Concurrence of Intraoperative Hypotension, Low Minimum Alveolar Concentration, and Low Bispectral Index Is Associated with Postoperative Death
10.1097/aln.0000000000000822 · 2015 · External reference
Electroencephalogram-based anaesthetic depth monitoring in laboratory animals
10.1258/la.2012.011135 · 2012 · External reference
Unresolved reference
External reference
Intraoperative nociception-antinociception monitors: A review from the veterinary perspective
10.1016/j.vaa.2019.09.006 · 2020 · External reference
Evaluation of the Parasympathetic Tone Activity (PTA) index to assess the analgesia/nociception balance in anaesthetised dogs
10.1016/j.rvsc.2017.05.009 · 2017 · External reference
Unresolved reference
External reference
Triple-low Alerts Do Not Reduce Mortality: A Real-time Randomized Trial
10.1097/aln.0000000000002480 · 2019 · External reference
Neural network mechanisms underlying general anesthesia: Cortical and subcortical nuclei
10.1007/s12264-024-01286-z · 2024 · External reference
The non-specific matrix thalamus facilitates the cortical information processing modes relevant for conscious awareness
10.1016/j.celrep.2023.112844 · 2023 · External reference
Effects of γ-aminobutyric acid type A receptor modulation by flumazenil on emergence from general anesthesia
10.1097/aln.0000000000001134 · 2016 · External reference
Electrocortical changes associating sedation and respiratory depression by the opioid analgesic fentanyl
10.1038/s41598-019-50613-2 · 2019 · External reference
Minimum alveolar concentration: A standard of anesthetic potency
10.1097/00000542-196511000-00010 · 1965 · External reference
Comparison of the minimum alveolar concentration of isoflurane in dogs determined by tail clamp and electrical stimulation
1988 · External reference
Determination and applications of MAC
10.1097/00000542-198010000-00008 · 1980 · External reference
Unresolved reference
External reference
Association of low blood pressure, low bispectral index and low minimum alveolar concentration of anaesthetic during surgery with postoperative 30-day mortality: A systemic review and meta-analysis
10.5152/tjar.2017.47154 · 2017 · External reference
10.1201/9781003353799
10.1201/9781003353799 · External reference
10.3390/ani13040664
10.3390/ani13040664 · External reference
10.3390/ani13213391
10.3390/ani13213391 · External reference
10.3389/fvets.2021.751949
10.3389/fvets.2021.751949 · External reference
Results of Preemptive Epidural Administration of Morphine with or without Bupivacaine in Dogs and Cats Undergoing Surgery: 265 Cases (1997–1999)
10.2460/javma.2002.221.666 · 2002 · External reference
Effects of a Prolonged Infusion of Fentanyl, with or Without Atropine, on the Minimum Alveolar Concentration of Isoflurane in Dogs
10.1111/vaa.12282 · 2016 · External reference
Increases in Mean Arterial Blood Pressure During Electrical Stimulation Are Unreliable Indicators of Anesthetic Depth Measured with Electroencephalogram in Dogs Anesthetized with Sevoflurane
10.2460/ajvr.24.08.0232 · 2025 · External reference
EEG Quantitation of Narcotic Effect: The Comparative Pharmacodynamics of Fentanyl and Alfentanil
10.1097/00000542-198503000-00005 · 1985 · External reference
Electroencephalographic Quantitation of Opioid Effect: Comparative Pharmacodynamics of Fentanyl and Sufentanil
10.1097/00000542-199101000-00007 · 1991 · External reference
An Electroencephalogram Biomarker of Fentanyl Drug Effects
10.1093/pnasnexus/pgac158 · 2022 · External reference
Pharmacokinetic/Pharmacodynamic Modelling of the EEG Effects of Opioids: The Role of Complex Biophase Distribution Kinetics
10.1016/j.ejps.2008.03.003 · 2008 · External reference
Distinct Cortical Signatures Associated with Sedation and Respiratory Rate Depression by Morphine in a Pediatric Population
10.1097/aln.0000000000001303 · 2016 · External reference
Monitoring anesthesia depth with patient state index during pediatric surgery
10.1111/pan.14711 · 2023 · External reference
Perioperative dynamic EEG patterns correlated with changes in cognitive subdomains
10.1016/j.cnp.2026.07.009 · 2026 · External reference
Neural network mechanisms underlying general anesthesia: Cortical and subcortical nuclei
10.1007/s12264-024-01286-z · ExternalCitation · doi-reference
The non-specific matrix thalamus facilitates the cortical information processing modes relevant for conscious awareness
10.1016/j.celrep.2023.112844 · ExternalCitation · doi-reference
Perioperative dynamic EEG patterns correlated with changes in cognitive subdomains
10.1016/j.cnp.2026.07.009 · ExternalCitation · doi-reference
Pharmacokinetic/Pharmacodynamic Modelling of the EEG Effects of Opioids: The Role of Complex Biophase Distribution Kinetics
10.1016/j.ejps.2008.03.003 · ExternalCitation · doi-reference
Evaluation of the Parasympathetic Tone Activity (PTA) index to assess the analgesia/nociception balance in anaesthetised dogs
10.1016/j.rvsc.2017.05.009 · ExternalCitation · doi-reference
Intraoperative nociception-antinociception monitors: A review from the veterinary perspective
10.1016/j.vaa.2019.09.006 · ExternalCitation · doi-reference
Electrocortical changes associating sedation and respiratory depression by the opioid analgesic fentanyl
10.1038/s41598-019-50613-2 · ExternalCitation · doi-reference
Prevention of Intraoperative Awareness in a High-Risk Surgical Population
10.1056/nejmoa1100403 · ExternalCitation · doi-reference
Mechanisms of action of inhaled anesthetics
10.1056/nejmra021261 · ExternalCitation · doi-reference
General anesthesia, sleep, and coma
10.1056/nejmra0808281 · ExternalCitation · doi-reference
An Electroencephalogram Biomarker of Fentanyl Drug Effects
10.1093/pnasnexus/pgac158 · ExternalCitation · doi-reference
Minimum alveolar concentration: A standard of anesthetic potency
10.1097/00000542-196511000-00010 · ExternalCitation · doi-reference
Determination and applications of MAC
10.1097/00000542-198010000-00008 · ExternalCitation · doi-reference
EEG Quantitation of Narcotic Effect: The Comparative Pharmacodynamics of Fentanyl and Alfentanil
10.1097/00000542-198503000-00005 · ExternalCitation · doi-reference
Electroencephalographic Quantitation of Opioid Effect: Comparative Pharmacodynamics of Fentanyl and Sufentanil
10.1097/00000542-199101000-00007 · ExternalCitation · doi-reference
The aging brain and anesthesia
10.1097/aco.0b013e328362d183 · ExternalCitation · doi-reference
Concurrence of Intraoperative Hypotension, Low Minimum Alveolar Concentration, and Low Bispectral Index Is Associated with Postoperative Death
10.1097/aln.0000000000000822 · ExternalCitation · doi-reference
Effects of γ-aminobutyric acid type A receptor modulation by flumazenil on emergence from general anesthesia
10.1097/aln.0000000000001134 · ExternalCitation · doi-reference
Distinct Cortical Signatures Associated with Sedation and Respiratory Rate Depression by Morphine in a Pediatric Population
10.1097/aln.0000000000001303 · ExternalCitation · doi-reference
Triple-low Alerts Do Not Reduce Mortality: A Real-time Randomized Trial
10.1097/aln.0000000000002480 · ExternalCitation · doi-reference
Understanding the effects of general anesthetics on cortical network activity using ex vivo preparations
10.1097/aln.0000000000002554 · ExternalCitation · doi-reference
Broadly applicable risk stratification system for predicting duration of hospitalization and mortality
10.1097/aln.0b013e3181f79a8d · ExternalCitation · doi-reference
Hospital stay and mortality are increased in patients having a “triple low” of low blood pressure, low bispectral index, and low minimum alveolar concentration of volatile anesthesia
10.1097/aln.0b013e31825683dc · ExternalCitation · doi-reference
Is “triple low” of low blood pressure, low bispectral index, and low minimum alveolar concentration of volatile anesthesia an independent predictor for postoperative mortality?
10.1097/aln.0b013e318278caf9 · ExternalCitation · doi-reference
Monitoring anesthesia depth with patient state index during pediatric surgery
10.1111/pan.14711 · ExternalCitation · doi-reference
Effects of a Prolonged Infusion of Fentanyl, with or Without Atropine, on the Minimum Alveolar Concentration of Isoflurane in Dogs
10.1111/vaa.12282 · ExternalCitation · doi-reference
10.1201/9781003353799
10.1201/9781003353799 · ExternalCitation · doi-reference
Electroencephalogram-based anaesthetic depth monitoring in laboratory animals
10.1258/la.2012.011135 · ExternalCitation · doi-reference
Increases in Mean Arterial Blood Pressure During Electrical Stimulation Are Unreliable Indicators of Anesthetic Depth Measured with Electroencephalogram in Dogs Anesthetized with Sevoflurane
10.2460/ajvr.24.08.0232 · ExternalCitation · doi-reference
Results of Preemptive Epidural Administration of Morphine with or without Bupivacaine in Dogs and Cats Undergoing Surgery: 265 Cases (1997–1999)
10.2460/javma.2002.221.666 · ExternalCitation · doi-reference
10.3389/fncir.2017.00044
10.3389/fncir.2017.00044 · ExternalCitation · doi-reference
10.3389/fvets.2021.751949
10.3389/fvets.2021.751949 · ExternalCitation · doi-reference
10.3390/ani13040664
10.3390/ani13040664 · ExternalCitation · doi-reference
10.3390/ani13213391
10.3390/ani13213391 · ExternalCitation · doi-reference
Association of low blood pressure, low bispectral index and low minimum alveolar concentration of anaesthetic during surgery with postoperative 30-day mortality: A systemic review and meta-analysis
10.5152/tjar.2017.47154 · ExternalCitation · doi-reference
