Research graph
References from Therapeutic Potential of the Deubiquitinase BRCC3 in Attenuating Ischemic Myocardial Injury and Ventricular Remodeling. Local targets link to admitted publications; unresolved targets remain external evidence.
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ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination
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The deubiquitinase OTUD1 suppresses secretory neutrophil polarization and ameliorates immunopathology of periodontitis
10.1002/advs.202303207 · 2023 · External reference
SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity
10.1038/s41467-018-04620-y · 2018 · External reference
Pellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks
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SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy
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10.1161/circulationaha.123.065344
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Loss of BRCC3 deubiquitinating enzyme leads to abnormal angiogenesis and is associated with syndromic moyamoya
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Modified citrus pectin ameliorates myocardial fibrosis and inflammation via suppressing galectin-3 and TLR4/MyD88/NF-κB signaling pathway
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Integrin beta-like 1 mediates fibroblast–cardiomyocyte crosstalk to promote cardiac fibrosis and hypertrophy
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The Ercc1 −/Δ mouse model of XFE progeroid syndrome undergoes accelerated retinal degeneration
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TREM2 macrophage promotes cardiac repair in myocardial infarction by reprogramming metabolism via SLC25A53
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Targeting NLRC5 in cardiomyocytes protects postinfarction cardiac injury by enhancing autophagy flux through the CAVIN1/CAV1 axis
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10.1093/cvr/cvy307
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Cardiomyocyte SMAD4-dependent TGF-β signaling is essential to maintain adult heart homeostasis
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10.1093/cvr/cvy131
10.1093/cvr/cvy131 · External reference
Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction
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The mechanism of OTUB1-mediated inhibition of ubiquitination
10.1038/nature10911 · 2012 · External reference
Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3
10.15252/embr.202256135 · 2023 · External reference
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BRCA1 is an essential regulator of heart function and survival following myocardial infarction
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Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair
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ER-phagy activation by AMFR attenuates cardiac fibrosis post-myocardial infarction via mTORC1 pathway
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Shenxiong Yixin decoction polysaccharides exert therapeutic effects against myocardial ischemia-reperfusion injury via intestinal exosomal microRNA-21 regulation
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