Research graph
References from Correlation of high PRDX4 expression with poor prognosis in patients with ESCA: Bioinformatics and in vitro validation. Local targets link to admitted publications; unresolved targets remain external evidence.
Involvement of the PRDX family and its clinical functions in different types of gastrointestinal cancer (review)
10.3892/or.2025.8923 · 2025 · External reference
Genomewide analysis of the CIII peroxidase family in sweet orange (Citrus sinensis) and expression profiles induced by Xanthomonas citri subsp. citri and hormones
2020 · External reference
PRDX1 Cys52Ser variant alleviates nonalcoholic steatohepatitis by reducing inflammation in mice
10.1016/j.molmet.2023.101789 · 2023 · External reference
PRDX4 improved aging-related delayed wound healing in mice
10.1016/j.jid.2021.04.015 · 2021 · External reference
Epidemiology of esophageal cancer in Japan and China
10.2188/jea.je20120162 · 2013 · External reference
Relationship between GLIM criteria and disease-specific symptoms and its impact on 5-year survival of esophageal cancer patients
10.1016/j.clnu.2021.08.008 · 2021 · External reference
Tumor-associated macrophage-derived exosomes LINC01592 induce the immune escape of esophageal cancer by decreasing MHC-I surface expression
10.1186/s13046-023-02871-2 · 2023 · External reference
Validation of the interaction between PRDX4 and TXNDC5 in gastric cancer and the significance of the PRDX4 gene in gastric cancer based on a data mining analysis
10.21037/tcr-23-904 · 2024 · External reference
Immune infiltration related PRDX4 facilitates the malignant features and drug resistance of breast cancer
10.1038/s41598-025-13361-0 · 2025 · External reference
NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4
10.1126/sciadv.abf7114 · 2021 · External reference
LncRNA THUMPD3-AS1 promotes the proliferation and migration of esophageal cancer cells through the miR-29a-3p/ELK1/PRDX4 signaling pathway
10.1016/j.seminoncol.2025.152350 · 2025 · External reference
UALCAN: A portal for facilitating tumour subgroup gene expression and survival analyses
10.1016/j.neo.2017.05.002 · 2017 · External reference
Sangerbox: A comprehensive, interaction-friendly clinical bioinformatics analysis platform
10.1002/imt2.36 · 2022 · External reference
The STRING database in 2023: Protein-protein association networks and functional enrichment analyses for any sequenced genome of interest
10.1093/nar/gkac1000 · 2023 · External reference
A comprehensive pan-cancer analysis reveals GRB7 as a potential diagnostic and prognostic biomarker
10.7759/cureus.74907 · 2024 · External reference
Mining expression and prognosis of topoisomerase isoforms in non-small-cell lung cancer by using Oncomine and Kaplan-Meier plotter
10.1371/journal.pone.0174515 · 2017 · External reference
Integrated genomic characterization of oesophageal carcinoma
10.1038/nature20805 · 2017 · External reference
PRDX4 overexpression is associated with poor prognosis in gastric cancer
10.3892/ol.2020.11468 · 2020 · External reference
New early gastric cancer marker PRDX4 promote the tumorigenesis and progression of gastric cancer via eliminating ROS
10.13345/j.cjb.190202 · 2020 · External reference
Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles
10.15252/embj.2018101266 · 2019 · External reference
Revealing Prdx4 as a potential diagnostic and therapeutic target for acute pancreatitis based on machine learning analysis
10.1186/s12920-024-01854-2 · 2024 · External reference
Endoplasmic reticulum stress and alterations of peroxiredoxins in aged hearts
10.1016/j.mad.2023.111859 · 2023 · External reference
ERO1-independent production of H2O2 within the endoplasmic reticulum fuels Prdx4-mediated oxidative protein folding
10.1083/jcb.201506123 · 2015 · External reference
Endoplasmic reticulum oxidative stress promotes glutathione-dependent oxidation of collagen-1A1 and promotes lung fibroblast activation
10.1165/rcmb.2023-0379oc · 2024 · External reference