Research graph
References from Targeting the DNHD1‑HDAC6 axis inactivates prostate cancer cell aggressiveness in vitro, suggesting potential therapeutic vulnerability. Local targets link to admitted publications; unresolved targets remain external evidence.
A circulating MicroRNA signature as a biomarker for prostate cancer in a high risk group
10.3390/jcm4071369 · 2015 · External reference
Cancer statistics, 2024
2024 · External reference
Prostate cancer in young men: An important clinical entity
10.1038/nrurol.2014.91 · 2014 · External reference
Prostate cancer
10.1038/s41572-020-00243-0 · 2021 · External reference
Cancer statistics, 2026
2026 · External reference
Prostate-specific antigen (PSA)-based population screening for prostate cancer: An evidence-based analysis
2015 · External reference
Diagnosis of prostate cancer via nanotechnological approach
2015 · External reference
Prevention and early detection of prostate cancer
10.1016/s1470-2045(14)70211-6 · 2014 · External reference
Robot-assisted surgery in a broader healthcare perspective: A difference-in-difference-based cost analysis of a national prostatectomy cohort
10.1136/bmjopen-2016-015580 · 2017 · External reference
A short-term cost-effectiveness study comparing robot-assisted laparoscopic and open retropubic radical prostatectomy
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Coiled coils: A highly versatile protein folding motif
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Clinical genomics expands the morbid genome of intellectual disability and offers a high diagnostic yield
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Exome sequencing of fetal anomaly syndromes: Novel phenotype-genotype discoveries
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Bi-allelic variants in DNHD1 cause flagellar axoneme defects and asthenoteratozoospermia in humans and mice
10.1016/j.ajhg.2021.11.022 · 2022 · External reference
New mutations in DNHD1 cause multiple morphological abnormalities of the sperm flagella
10.3390/ijms24032559 · 2023 · External reference
Exposure to low levels of lead in utero and umbilical cord blood DNA methylation in project viva: An epigenome-wide association study
10.1289/ehp1246 · 2017 · External reference
Cytoplasmic dynein heavy chain: The servant of many masters
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Whole exome sequencing identification of novel candidate genes in patients with proliferative diabetic retinopathy
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Differentially methylated DNA regions and left ventricular hypertrophy in african americans: A HyperGEN study
10.3390/genes13101700 · 2022 · External reference
LOF variants identifying candidate genes of laterality defects patients with congenital heart disease
10.1371/journal.pgen.1010530 · 2022 · External reference
Genomic characteristics of pancreatic squamous cell carcinoma, an investigation by using high throughput sequencing after in-solution hybrid capture
10.18632/oncotarget.14678 · 2017 · External reference
Effective treatment of a BRAF V600E-mutant epithelioid glioblastoma patient by vemurafenib: A case report
10.1097/cad.0000000000001130 · 2022 · External reference
High-throughput sequencing reveals that rotundine inhibits colorectal cancer by regulating prognosis-related genes
10.3390/jpm13030550 · 2023 · External reference
Histone deacetylase 6: A potential therapeutic target for drug development
10.1016/j.bioorg.2025.108932 · 2025 · External reference
The regulatory mechanisms and treatment of HDAC6 in immune dysregulation diseases
10.3389/fimmu.2025.1653588 · 2025 · External reference
Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly
10.1038/srep12917 · 2015 · External reference
Discovery of a novel AR/HDAC6 dual inhibitor for prostate cancer treatment
10.18632/aging.202554 · 2021 · External reference
Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6
10.1073/pnas.0908908106 · 2009 · External reference
HDAC6 regulates androgen receptor hypersensitivity and nuclear localization via modulating Hsp90 acetylation in castration-resistant prostate cancer
10.1210/me.2009-0188 · 2009 · External reference
Recent development of selective inhibitors targeting the HDAC6 as anti-cancer drugs: Structure, function and design
10.1016/j.bioorg.2023.106622 · 2023 · External reference
HDAC6 as privileged target in drug discovery: A perspective
10.1016/j.phrs.2020.105274 · 2021 · External reference
Implications of the KHDC4-TRAF2 axis in the context of prostate cancer prognosis
2025 · External reference
The prognostic and neuroendocrine implications of SLC25A29-mediated biomass signature in prostate cancer
10.1007/s11357-025-01538-4 · 2025 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2(−Delta Delta C(T)) method
10.1006/meth.2001.1262 · 2001 · External reference
The role of fructose 1,6-bisphosphate-mediated glycolysis/gluconeogenesis genes in cancer prognosis
10.18632/aging.204010 · 2022 · External reference
The CHST11 gene is linked to lung cancer and pulmonary fibrosis
10.1002/jgm.3451 · 2022 · External reference
The cytoplasmic expression of FSTL3 correlates with colorectal cancer progression, metastasis status and prognosis
10.1111/jcmm.17690 · 2023 · External reference
The activation of EP300 by F11R leads to EMT and acts as a prognostic factor in triple-negative breast cancers
10.1002/cjp2.313 · 2023 · External reference
Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle
10.1038/ncomms9087 · 2015 · External reference
HDAC6: A key regulator of cytoskeleton, cell migration and cell-cell interactions
10.1016/j.tcb.2008.04.003 · 2008 · External reference
Role of HDAC6 in carcinomas
10.1007/s12672-026-04391-9 · 2026 · External reference
New insights into the androgen-targeted therapies and epigenetic therapies in prostate cancer
10.1155/2011/918707 · 2011 · External reference
A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin-induced apoptosis in castration-resistant prostate cancer
10.1002/pros.24678 · 2024 · External reference
Potential of histone deacetylase inhibitors in the control and regulation of prostate, breast and ovarian cancer
10.3389/fchem.2022.948217 · 2022 · External reference
Mixed signals from the cell's antennae: Primary cilia in cancer
10.15252/embr.201846589 · 2018 · External reference
Primary cilia as dynamic and diverse signalling hubs in development and disease
10.1038/s41576-023-00587-9 · 2023 · External reference
Patterns of ciliation and ciliary signaling in cancer
10.1007/112_2020_36 · 2023 · External reference
Primary cilia in cancer: Structures, functions, mechanisms, and therapeutic implications
2025 · External reference
Primary cilia and cancer: A tale of many faces
10.1038/s41388-025-03416-x · 2025 · External reference
Multifaceted role of primary cilia and ciliary proteins: A potential nexus for hedgehog signaling and prostate cancer
10.1016/j.bbadis.2025.168120 · 2026 · External reference
Primary cilia: A link between hormone signalling and endocrine-related cancers?
10.1042/bst20160149 · 2016 · External reference
GLI3: A mediator of genetic diseases, development and cancer
10.1186/s12964-020-00540-x · 2020 · External reference
Epigenetic regulation of androgen receptor signaling in prostate cancer
10.4161/epi.5.2.10778 · 2010 · External reference
A dual CYP17A1/HDAC6 inhibitor for targeted prostate cancer therapy
10.1096/fj.202502614r · 2025 · External reference
