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2005 · External reference

Addressing tobacco use disorder in smokers in early remission from alcohol dependence: The case for integrating smoking cessation services in substance use disorder treatment programs

2010 · External reference

Comorbid Cigarette and Alcohol Addiction

1998 · External reference

Alcoholism and smoking

1990 · External reference

Nicotine dependence and withdrawal in alcoholic and nonalcoholic ever-smokers

1997 · External reference

Cancer risk associated with alcohol and tobacco use: focus on upper aero-digestive tract and liver

2006 · External reference

Co-occurrence of alcohol and cigarette use among adolescents

2001 · External reference

Association of the neuronal nicotinic receptor β2 subunit gene (CHRNB2) with subjective responses to alcohol and nicotine

2007 · External reference

The CHRNA5/A3/B4 Gene Cluster Variability as an Important Determinant of Early Alcohol and Tobacco Initiation in Young Adults

External reference

Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions

2012 · External reference

Chronic exposure to nicotine upregulates the human (alpha)4(beta)2 nicotinic acetylcholine receptor function

2001 · External reference

Critical elements determining diversity in agonist binding and desensitization of neuronal nicotinic acetylcholine receptors

1998 · External reference

Chronic nicotine exposure upregulates nicotinic receptors by a novel mechanism

2005 · External reference

Smoking upregulates α4β2* nicotinic acetylcholine receptors in the human brain

2008 · External reference

Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area

1994 · External reference

Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs

1996 · External reference

The Molecular Biology of Neuronal Nicotinic Acetylcholine Receptors

1997 · External reference

Neuronal nicotinic receptors: from structure to pathology

2004 · External reference

Muscle and neuronal nicotinic acetylcholine receptors

2007 · External reference

Relating neuronal nicotinic acetylcholine receptor subtypes defined by subunit composition and channel function

2003 · External reference

Nicotinic acetylcholine subunit mRNA expression in dopaminergic neurons of the rat substantia nigra and ventral tegmental area

1998 · External reference

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

1993 · External reference

Expression of neuronal nicotinic acetylcholine receptor subunit mRNAs within midbrain dopamine neurons

2002 · External reference

Varenicline: An α4β2 Nicotinic Receptor Partial Agonist for Smoking Cessation

2005 · External reference

β2 subunit-containing nicotinic receptors mediate the enhancing effect of nicotine on trace cued fear conditioning in C57BL/6 mice

2007 · External reference

Neurochemical and behavioral studies on ethanol and nicotine interactions

2004 · External reference

Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms

2007 · External reference

Cognitive Deficits in Schizophrenia: Focus on Neuronal Nicotinic Acetylcholine Receptors and Smoking

2007 · External reference

β2 subunit containing acetylcholine receptors mediate nicotine withdrawal deficits in the acquisition of contextual fear conditioning

2008 · External reference

Nicotine Improves Sustained Attention in Mice: Evidence for Involvement of the α7 Nicotinic Acetylcholine Receptor

2004 · External reference

Nicotinic acetylcholine receptors in the ventral tegmental area mediate the dopamine activating and reinforcing properties of ethanol cues

2007 · External reference

Varenicline, an 4beta2 nicotinic acetylcholine receptor partial agonist, selectively decreases ethanol consumption and seeking

2007 · External reference

Mecamylamine and Ethanol Preference in Healthy Volunteers

2005 · External reference

Neuronal nicotinic receptor ligands modulate chronic nicotine-induced ethanol consumption in C57BL/6J mice

2012 · External reference

Nicotinic Acetylcholine Receptors are Sensors for Ethanol in Lung Fibroblasts

2013 · External reference

Neuropharmacology of alcohol addiction

2008 · External reference

Alcohol's actions on neuronal nicotinic acetylcholine receptors

2006 · External reference

Ethanol modulation of nicotinic acetylcholine receptor currents in cultured cortical neurons

1999 · External reference

Chronic Ethanol Treatment Decreases [3H]Epibatidine and [3H]Nicotine Binding and Differentially Regulates mRNA Levels of Nicotinic Acetylcholine Receptor Subunits Expressed in M10 and SH-SY5Y Neuroblastoma Cells

1998 · External reference

Acetylcholine and Alcohol Sensitivity of Neuronal Nicotinic Acetylcholine Receptors: Mutations in Transmembrane Domains

2002 · External reference

Dual action of n-alcohols on neuronal nicotinic acetylcholine receptors

2001 · External reference

Ethanol increases agonist affinity for nicotinic receptors from Torpedo

1989 · External reference

Potent modulation of neuronal nicotinic acetylcholine receptor-channel by ethanol

1996 · External reference

Effects of ethanol on recombinant human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes

1999 · External reference

Alpha4beta2* Nicotinic Acetylcholine Receptors Modulate the Effects of Ethanol and Nicotine on the Acoustic Startle Response

2003 · External reference

Interaction of the Nicotinic Cholinergic System with Ethanol Withdrawal

2004 · External reference

Prepulse Inhibition of the Startle Reflex: Preliminary Study of the Effects of a Low Dose of Alcohol in Humans

1997 · External reference

Dual Action of n-Butanol on Neuronal Nicotinic alpha4beta2 Acetylcholine Receptors

2003 · External reference

Alcohol Modulation of Neuronal Nicotinic Acetylcholine Receptors Is alpha Subunit Dependent

2002 · External reference

Single-Channel Analyses of Ethanol Modulation of Neuronal Nicotinic Acetylcholine Receptors

2004 · External reference

Ethanol inhibition of nicotinic acetylcholine type alpha 7 receptors involves the amino-terminal domain of the receptor

1996 · External reference

Additive Effects of Endogenous Cannabinoid Anandamide and Ethanol on 7-Nicotinic Acetylcholine Receptor-Mediated Responses in Xenopus Oocytes

2005 · External reference

Differential modulation of rat neuronal nicotinic receptor subtypes by acute application of ethanol

1997 · External reference

Nicotinic Acetylcholine Receptors Containing the α4 Subunit Modulate Alcohol Reward

2013 · External reference

The α5 Neuronal Nicotinic Acetylcholine Receptor Subunit Plays an Important Role in the Sedative Effects of Ethanol But Does Not Modulate Consumption in Mice

2013 · External reference

The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse

2013 · External reference

Sites of excitatory and inhibitory actions of alcohols on neuronal alpha2beta4 nicotinic acetylcholine receptors

2003 · External reference

Effects of alcohols and volatile anesthetics on the activation of nicotinic acetylcholine receptor channels

1994 · External reference

Ethanol stabilizes the open channel state of the Torpedo nicotinic acetylcholine receptor

1994 · External reference

Sensitivity of N-Methyl-D-Aspartate (NMDA) and Nicotinic Acetylcholine Receptors to Ethanol and Pyrazole

1991 · External reference

Novel modulation of a nicotinic receptor channel mutant reveals that the open state is stabilized by ethanol

1999 · External reference

Nicotinic Receptor Pore Mutations Create a Sensitive Inhibitory Site for Ethanol

2000 · External reference

Octanol Modulation of Neuronal Nicotinic Acetylcholine Receptor Single Channels

2004 · External reference

Acute Alcohol Action and Desensitization of Ligand-Gated Ion Channels

2009 · External reference

An epidemiologic analysis of co-occurring alcohol and tobacco use and disorders: findings from the National Epidemiologic Survey on Alcohol and Related Conditions

2006 · External reference

Posttraumatic stress disorder; combat exposure; and nicotine dependence, alcohol dependence, and major depression in male twins

2008 · External reference

The Genetic Components of Alcohol and Nicotine Co-Addiction: From Genes to Behavior

External reference

Common Genetic Vulnerability for Nicotine and Alcohol Dependence in Men

1999 · External reference

Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

2009 · External reference

A Polymorphism in the alpha4 Nicotinic Receptor Gene (Chrna4) Modulates Enhancement of Nicotinic Receptor Function by Ethanol

2003 · External reference

Bimodal modulation by nicotine of anxiety in the social interaction test: Role of the dorsal hippocampus

1998 · External reference

Long sleep and short sleep mice differ in nicotine-stimulated 86Rb+ efflux and alpha4 nicotinic receptor subunit cDNA sequence

2001 · External reference

Potential regulation of nicotine and ethanol actions by α4-containing nicotinic receptors

2001 · External reference

Partial Agonists of the α3β4* Neuronal Nicotinic Acetylcholine Receptor Reduce Ethanol Consumption and Seeking in Rats

2011 · External reference

α7 Nicotinic acetylcholine receptor knockout selectively enhances ethanol-, but not β-amyloid-induced neurotoxicity

2005 · External reference

Deletion of the alpha7 Nicotinic Receptor Subunit Gene Results in Increased Sensitivity to Several Behavioral Effects Produced by Alcohol

2005 · External reference

Common genetic and environmental vulnerability for alcohol and tobacco use in a volunteer sample of older female twins

2001 · External reference

Genetic and Environmental Vulnerabilities Underlying Adolescent Substance Use and Problem Use: General or Specific?

2006 · External reference

Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction

2008 · External reference

Association of polymorphisms in nicotinic acetylcholine receptor α4 subunit gene (CHRNA4), μ-opioid receptor gene (OPRM1), and ethanol-metabolizing enzyme genes with alcoholism in Korean patients

2004 · External reference

Association of nAChR gene haplotypes with heavy alcohol use and body mass

2009 · External reference

Modulation of ethanol consumption by genetic and pharmacological manipulation of nicotinic acetylcholine receptors in mice

2010 · External reference

Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption

2010 · External reference

Nicotinic mechanisms involved in the dopamine activating and reinforcing properties of ethanol

2000 · External reference

Nicotine Dependence and Alcoholism Epidemiology and Treatment

1992 · External reference

Mecamylamine Attenuates the Subjective Stimulant-Like Effects of Alcohol in Social Drinkers

2003 · External reference

Cholinergic Receptor System as a Target for Treating Alcohol Abuse and Dependence

2012 · External reference

Cellular mechanisms of nicotine addiction

2001 · External reference

Role of the subunit composition of central nicotinic acetylcholine receptors for the stimulatory and dopamine-enhancing effects of ethanol

2006 · External reference

Frontal cortical α7 and α4β2 nicotinic acetylcholine receptors in working and reference memory

2007 · External reference

Varenicline ameliorates ethanol-induced deficits in learning in C57BL/6 mice

2008 · External reference

Dorsal hippocampal α7 and α4β2 nicotinic receptors and memory

2006 · External reference

Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis

1989 · External reference

The effects of nicotine on locomotor activity in non-tolerant and tolerant rats

1983 · External reference

The mesolimbic dopamine-activating properties of ethanol are antagonized by mecamylamine

1993 · External reference

Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment

1996 · External reference

Accumbal dopamine overflow after ethanol: Localization of the antagonizing effect of mecamylamine

1997 · External reference

Voluntary ethanol intake in the rat and the associated accumbal dopamine overflow are blocked by ventral tegmental mecamylamine

1998 · External reference

Involvement of Nicotinic Receptors in Alcohol Self-Administration

2000 · External reference

Effects of Nicotine and Mecamylamine Microinjections into the Nucleus Accumbens on Ethanol and Sucrose Self-Administration

1998 · External reference

Ethanol elevates accumbal dopamine levels via indirect activation of ventral tegmental nicotinic acetylcholine receptors

2003 · External reference

The influence of mecamylamine on ethanol and sucrose self-administration

2009 · External reference

Modulation of ethanol drinking-in-the-dark by mecamylamine and nicotinic acetylcholine receptor agonists in C57BL/6J mice

2009 · External reference

Effects of subunit selective nACh receptors on operant ethanol self-administration and relapse-like ethanol-drinking behavior

2009 · External reference

Nicotinic Acetylcholine Receptors in the Anterior, but Not Posterior, Ventral Tegmental Area Mediate Ethanol-Induced Elevation of Accumbal Dopamine Levels

2008 · External reference

Acquisition, expression, and reinstatement of ethanol-induced conditioned place preference in mice: effects of exposure to stress and modulation by mecamylamine

2012 · External reference

Varenicline, a partial agonist at neuronal nicotinic acetylcholine receptors, reduces nicotine-induced increases in 20% ethanol operant self-administration in Sprague-Dawley rats

2011 · External reference

Effects of Mecamylamine on Alcohol Consumption and Preference in Male C57BL/6J Mice

2009 · External reference

Inhibitory influence of mecamylamine on ethanol withdrawal-induced symptoms in C57BL/6J mice

2010 · External reference

Inhibitory influence of mecamylamine on the development and the expression of ethanol-induced locomotor sensitization in mice

2010 · External reference

Role of different nicotinic acetylcholine receptors in mediating behavioral and neurochemical effects of ethanol in mice

2002 · External reference

Ethanol-induced locomotor activity: involvement of central nicotinic acetylcholine receptors?

1992 · External reference

Varenicline and cytisine: two nicotinic acetylcholine receptor ligands reduce ethanol intake in University of Chile bibulous rats

2013 · External reference

Potential therapeutic uses of mecamylamine and its stereoisomers

2013 · External reference

Mecamylamine combined with nicotine skin patch facilitates smoking cessation beyond nicotine patch treatment alone

1994 · External reference

Nicotine-mecamylamine treatment for smoking cessation: The role of pre-cessation therapy

1998 · External reference

Mecamylamine Modifies the Pharmacokinetics and Reinforcing Effects of Alcohol

2002 · External reference

Varenicline Potentiates Alcohol-Induced Negative Subjective Responses and Offsets Impaired Eye Movements

2012 · External reference

A preliminary investigation of varenicline for heavy drinking smokers

2011 · External reference

Varenicline Reduces Alcohol Self-Administration in Heavy-Drinking Smokers

2009 · External reference

Varenicline decreases alcohol consumption in heavy-drinking smokers

2012 · External reference

Varenicline attenuates cue-induced relapse to alcohol, but not nicotine seeking, while reducing inhibitory response control

2011 · External reference

Varenicline Treatment of Concurrent Alcohol and Nicotine Dependence in Schizophrenia

2013 · External reference

Efficacy of Varenicline, an 4beta2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation: A Randomized Controlled Trial

2006 · External reference

Updated US Smoking Cessation Guideline Advises Counseling, Combining Therapies

2008 · External reference