Research graph
References from Clinical Translation of Mesenchymal Stem Cells to Medicinal Signaling Cells: Origins, Clinical Applications, and the Future of Regenerative Medicine–2026 Arnold I. Caplan Award for Distinguished Research in Orthobiologics. Local targets link to admitted publications; unresolved targets remain external evidence.
Muscle stem cells differentiate into haematopoietic lineages but retain myogenic potential
10.1038/ncb1008 · 2003 · External reference
Muscle-derived stem cells: Potential for muscle regeneration
10.1002/bdrc.10020 · 2003 · External reference
Identification of a novel population of muscle stem cells in mice: Potential for muscle regeneration
10.1083/jcb.200108150 · 2002 · External reference
A perivascular origin for mesenchymal stem cells in multiple human organs
10.1016/j.stem.2008.07.003 · 2008 · External reference
Mesenchymal stem cells: Time to change the name
10.1002/sctm.17-0051 · 2017 · External reference
Differential myocardial infarct repair with muscle stem cells compared to myoblasts
10.1016/j.ymthe.2005.07.686 · 2005 · External reference
A relationship between vascular endothelial growth factor, angiogenesis, and cardiac repair after muscle stem cell transplantation into ischemic hearts
10.1016/j.jacc.2007.04.100 · 2007 · External reference
Cartilage repair in a rat model of osteoarthritis through intraarticular transplantation of muscle-derived stem cells expressing bone morphogenetic protein 4 and soluble Flt-1
10.1002/art.24443 · 2009 · External reference
Blocking vascular endothelial growth factor with soluble Flt-1 improves the chondrogenic potential of mouse skeletal muscle-derived stem cells
10.1002/art.24153 · 2009 · External reference
Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4
10.1172/jci15153 · 2002 · External reference
Prospective identification of myogenic endothelial cells in human skeletal muscle
10.1038/nbt1334 · 2007 · External reference
All MSCs are pericytes?
10.1016/j.stem.2008.08.008 · 2008 · External reference
Adult mesenchymal stem cells for tissue engineering versus regenerative medicine
10.1002/jcp.21200 · 2007 · External reference
10.1186/scrt72 · 2011 · Admitted local publication
Effect of VEGF on the regenerative capacity of muscle stem cells in dystrophic skeletal muscle
10.1038/mt.2009.136 · 2009 · External reference
Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model
10.1038/ncomms1611 · 2012 · External reference
Muscle-derived stem/progenitor cell dysfunction in Zmpste24-deficient progeroid mice limits muscle regeneration
10.1186/scrt183 · 2013 · External reference
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
10.1038/nature03260 · 2005 · External reference
Enhancement of myogenic potential of muscle progenitor cells and muscle healing during pregnancy
10.1096/fj.202001914r · 2021 · External reference
Targeting cellular senescence prevents age-related bone loss in mice
10.1038/nm.4385 · 2017 · External reference
Cellular senescence: A translational perspective
10.1016/j.ebiom.2017.04.013 · 2017 · External reference
Cellular expansion of MSCs: Shifting the regenerative potential
10.1111/acel.13759 · 2023 · External reference
Socializing with the neighbors: Stem cells and their niche
10.1016/s0092-8674(04)00255-7 · 2004 · External reference
Stem cells and niches: Mechanisms that promote stem cell maintenance throughout life
10.1016/j.cell.2008.01.038 · 2008 · External reference
RESULTS: From a randomized clinical trial evaluating the senolytic fisetin for treating knee osteoarthritis
10.1016/j.joca.2025.02.667 · 2025 · External reference
Attenuation of the progression of articular cartilage degeneration by inhibition of TGF-β1 signaling in a mouse model of osteoarthritis
10.1016/j.ajpath.2015.07.003 · 2015 · External reference
Potential usefulness of losartan as an antifibrotic agent and adjunct to platelet-rich plasma therapy to improve muscle healing and cartilage repair and prevent adhesion formation
10.3928/01477447-20180806-05 · 2018 · External reference
Gathering orthobiologic real-word evidence using registries and biorepositories: Proceedings of the American Academy of Orthopaedic Surgeons-Biologic Association Symposium November, 2022. JAAOS-Journal of the American Academy of Orthopaedic Surgeons
2022 · External reference
The microRNA regulatory landscape of MSC-derived exosomes: A systems view
10.1038/s41598-018-19581-x · 2018 · External reference
Role of microRNA shuttled in small extracellular vesicles derived from mesenchymal stem/stromal cells for osteoarticular disease treatment
10.3389/fimmu.2021.768771 · 2021 · External reference
Systemic blockade of transforming growth factor-beta signaling augments the efficacy of immunogene therapy
10.1158/0008-5472.can-08-1494 · 2008 · External reference
Antitransforming growth factor-beta therapy in fibrosis: Recent progress and implications for systemic sclerosis
10.1097/bor.0b013e32830e48e8 · 2008 · External reference
In vitro analysis of genome-engineered muscle-derived stem cells for autoregulated anti-inflammatory and antifibrotic activity
10.1002/jor.25311 · 2022 · External reference
Genome engineering of stem cells for autonomously regulated, closed-loop delivery of biologic drugs
10.1016/j.stemcr.2017.03.022 · 2017 · External reference
Anthocyanins and musculoskeletal diseases: Mechanisms and therapeutic potential
10.3389/fnut.2025.1602034 · 2025 · External reference
Protocatechuic acid induces expression of osteogenic genes in human osteoblast cultures: Implications for the treatment of osteoporosis and fractures
10.26502/josm.511500233 · 2025 · External reference
Protocatechuic acid inhibits proliferation, migration and inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes
10.1080/21691401.2020.1776307 · 2020 · External reference
Mechanisms of skeletal muscle atrophy and molecular circuitry of stem cell fate in skeletal muscle regeneration and aging
10.1093/gerona/glad023 · 2023 · External reference
Combined use of bone marrow-derived mesenchymal stromal cells (BM-MSCs) and platelet rich plasma (PRP) stimulates proliferation and differentiation of myoblasts in vitro: New therapeutic perspectives for skeletal muscle repair/regeneration
10.1007/s00441-018-2792-3 · 2018 · External reference
PRP and BMAC for musculoskeletal conditions via biomaterial carriers
10.3390/ijms20215328 · 2019 · External reference
