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References from RATIONAL APPROACHES FOR ENGINEERING NOVEL FUNCTIONALITIES IN CARBON-CARBON BOND FORMING ENZYMES. Local targets link to admitted publications; unresolved targets remain external evidence.
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Redesign of the Phosphate Binding Site of L-Rhamnulose- 1-Phosphate Aldolase towards a Dihydroxyacetone Dependent Aldolase
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Redesigning the active site of transaldolase TalB from Escherichia coli: new variants with improved affinity towards nonphosphorylated substrates
10.1002/cbic.200900720 · 2010 · External reference
Catalytic action of fuculose 1-phosphate aldolase (class II) as derived from structure-directed mutagenesis
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Structure-guided minimalist redesign of the L-fuculose-1-phosphate aldolase active site: expedient synthesis of novel polyhydroxylated pyrrolizidines and their inhibitory properties against glycosidases and intestinal disaccharidases
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A Mutant D-Fructose-6-Phosphate Aldolase (Ala129Ser) with Improved Affinity towards Dihydroxyacetone for the Synthesis of Polyhydroxylated Compounds
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Benzophenone synthase and chalcone synthase from Hypericum androsaemum cell cultures: cDNA cloning, functional expression, and site-directed mutagenesis of two polyketide synthases
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Comparison of two metal-dependent pyruvate aldolases related by convergent evolution: substrate specificity, kinetic mechanism, and substrate channeling
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Rational design of stereoselectivity in the class II pyruvate aldolase BphI
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Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases
10.1042/bj20061419 · 2007 · External reference
Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis
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Evidence that thienamycin biosynthesis proceeds via C-5 epimerization: ThnE catalyzes the formation of (2S,5S)-trans-carboxymethylproline
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Evidence for a two-base mechanism involving tyrosine-265 from arginine-219 mutants of alanine racemase
10.1021/bi982924t · 1999 · External reference
Tyrosine 265 of alanine racemase serves as a base abstracting alpha-hydrogen from L-alanine: the counterpart residue to lysine 39 specific to D-alanine
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Physically associated enzymes produce and metabolize 2-hydroxy-2,4-dienoate, a chemically unstable intermediate formed in catechol metabolism via meta cleavage in Pseudomonas putida
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The structural basis for the perturbed pKa of the catalytic base in 4-oxalocrotonate tautomerase: kinetic and structural effects of mutations of Phe-50
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The polypeptide chain fold in tyrosine phenol-lyase, a pyridoxal-5′-phosphate-dependent enzyme
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Production of L-phenylacetylcarbinol (L-PAC) from benzaldehyde using partially purified pyruvate decarboxylase (PDC)
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Conversion of pyruvate decarboxylase into an enantioselective carboligase with biosynthetic potential
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10.1016/j.bmc.2005.12.022
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10.1038/nbt.2109
10.1038/nbt.2109 · External reference
