Research graph
References from COMBINATORIAL APPROACHES FOR INVERSE METABOLIC ENGINEERING APPLICATIONS. Local targets link to admitted publications; unresolved targets remain external evidence.
Strategies and challenges in metabolic engineering
10.1111/j.1749-6632.1990.tb24230.x · 1990 · External reference
10.1002/bit.260260210
10.1002/bit.260260210 · External reference
10.1038/nbt1094-994
10.1038/nbt1094-994 · External reference
10.1146/annurev.biophys.37.032807.125832
10.1146/annurev.biophys.37.032807.125832 · External reference
10.1016/j.copbio.2009.08.005
10.1016/j.copbio.2009.08.005 · External reference
10.1146/annurev.genom.2.1.343
10.1146/annurev.genom.2.1.343 · External reference
Synthetic biology: new engineering rules for an emerging discipline
10.1038/msb4100073 · 2006 · External reference
10.1126/science.1190719
10.1126/science.1190719 · External reference
10.1016/j.copbio.2008.08.007
10.1016/j.copbio.2008.08.007 · External reference
10.1002/biot.201100085
10.1002/biot.201100085 · External reference
Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae
10.1038/nchembio.105 · 2008 · External reference
10.1038/nature04640
10.1038/nature04640 · External reference
10.1021/cr960027u
10.1021/cr960027u · External reference
10.1038/nature06450
10.1038/nature06450 · External reference
10.1038/nature11478
10.1038/nature11478 · External reference
Process design for microbial plastic factories: metabolic engineering of polyhydroxyalkanoates
10.1016/j.copbio.2003.09.002 · 2003 · External reference
10.1002/(sici)1097-0290(19961005)52:1<109::aid-bit11>3.0.co;2-j
10.1002/(sici)1097-0290(19961005)52:1<109::aid-bit11>3.0.co;2-j · External reference
Isolation and characterization of ethanol-tolerant mutants of Escherichia coli KO11 for fuel ethanol production
10.1038/sj.jim.2900496 · 1998 · External reference
Evolution, genomic analysis, and reconstruction of isobutanol tolerance in Escherichia coli
10.1038/msb.2010.98 · 2010 · External reference
10.1073/pnas.0803151105
10.1073/pnas.0803151105 · External reference
Engineering and adaptive evolution of Escherichia coli for d-lactate fermentation reveals GatC as a xylose transporter
10.1016/j.ymben.2012.07.007 · 2012 · External reference
10.1006/jmbi.1996.0399
10.1006/jmbi.1996.0399 · External reference
Novel redox potential-based screening strategy for rapid isolation of Klebsiella pneumoniae mutants with enhanced 1,3-propanediol-producing capability
10.1128/aem.02857-06 · 2007 · External reference
10.1073/pnas.1103219108
10.1073/pnas.1103219108 · External reference
10.1111/j.1567-1364.2012.00808.x
10.1111/j.1567-1364.2012.00808.x · External reference
Impact of ‘ome’ analyses on inverse metabolic engineering
10.1016/j.ymben.2003.11.005 · 2004 · External reference
10.1016/j.ymben.2011.08.004
10.1016/j.ymben.2011.08.004 · External reference
10.1016/j.ymben.2010.11.002
10.1016/j.ymben.2010.11.002 · External reference
10.1002/pro.39
10.1002/pro.39 · External reference
10.1038/nbt1101-1060
10.1038/nbt1101-1060 · External reference
10.1038/nbt1083
10.1038/nbt1083 · External reference
10.1002/bit.22097
10.1002/bit.22097 · External reference
Screening of Bacillus subtilis transposon mutants with altered riboflavin production
10.1016/j.ymben.2008.06.002 · 2008 · External reference
Identification of gene disruptions for increased poly-3-hydroxybutyrate accumulation in Synechocystis PCC 6803
10.1002/btpr.228 · 2009 · External reference
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection
10.1038/msb4100050 · 2006 · External reference
10.1126/science.285.5429.901
10.1126/science.285.5429.901 · External reference
Carotenoid-based phenotypic screen of the yeast deletion collection reveals new genes with roles in isoprenoid production
2012 · External reference
10.1002/bit.22988
10.1002/bit.22988 · External reference
Improvement of xylose uptake and ethanol production in recombinant Saccharomyces cerevisiae through an inverse metabolic engineering approach
10.1128/aem.71.12.8249-8256.2005 · 2005 · External reference
Identification of gene targets eliciting improved alcohol tolerance in Saccharomyces cerevisiae through inverse metabolic engineering
10.1016/j.jbiotec.2010.06.006 · 2010 · External reference
Genomic library screens for genes involved in n-butanol tolerance in Escherichia coli
10.1371/journal.pone.0017678 · 2011 · External reference
10.1016/j.ymben.2010.12.001
10.1016/j.ymben.2010.12.001 · External reference
10.1016/j.ymben.2007.03.003
10.1016/j.ymben.2007.03.003 · External reference
10.1016/j.ymben.2012.05.001
10.1016/j.ymben.2012.05.001 · External reference
A genomic-library based discovery of a novel, possibly synthetic, acid-tolerance mechanism in Clostridium acetobutylicum involving non-coding RNAs and ribosomal RNA processing
10.1016/j.ymben.2009.12.004 · 2010 · External reference
10.1093/dnares/dsi012
10.1093/dnares/dsi012 · External reference
10.1101/gr.6037607
10.1101/gr.6037607 · External reference
10.1073/pnas.1012108108
10.1073/pnas.1012108108 · External reference
10.1128/aem.00963-10
10.1128/aem.00963-10 · External reference
10.1111/j.1574-6941.2008.00613.x
10.1111/j.1574-6941.2008.00613.x · External reference
Coexisting/Coexpressing Genomic Libraries (CoGeL) identify interactions among distantly located genetic loci for developing complex microbial phenotypes
10.1093/nar/gkr817 · 2011 · External reference
10.1016/j.cbpa.2008.01.017
10.1016/j.cbpa.2008.01.017 · External reference
Custom DNA-binding proteins and artificial transcription factors
10.2174/1568026033452384 · 2003 · External reference
10.1073/pnas.110149297
10.1073/pnas.110149297 · External reference
10.1074/jbc.m506654200
10.1074/jbc.m506654200 · External reference
Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins
10.1021/bi026806o · 2003 · External reference
10.1038/nbt868
10.1038/nbt868 · External reference
Phenotypic alteration and target gene identification using combinatorial libraries of zinc finger proteins in prokaryotic cells
10.1128/jb.187.15.5496-5499.2005 · 2005 · External reference
10.1002/bit.22989
10.1002/bit.22989 · External reference
Phenotypic engineering by reprogramming gene transcription using novel artificial transcription factors in Escherichia coli
10.1093/nar/gkn449 · 2008 · External reference
Global transcription machinery engineering: a new approach for improving cellular phenotype
10.1016/j.ymben.2006.12.002 · 2007 · External reference
10.1126/science.1131969
10.1126/science.1131969 · External reference
10.1111/j.1365-2958.2005.04624.x
10.1111/j.1365-2958.2005.04624.x · External reference
10.1016/0022-2836(89)90567-6
10.1016/0022-2836(89)90567-6 · External reference
Altered promoter recognition by mutant forms of the sigma 70 subunit of Escherichia coli RNA polymerase
10.1016/0022-2836(89)90568-8 · 1989 · External reference
10.1002/bit.21947
10.1002/bit.21947 · External reference
10.1128/aem.01888-08
10.1128/aem.01888-08 · External reference
10.1073/pnas.0712177105
10.1073/pnas.0712177105 · External reference
10.1002/bit.24411
10.1002/bit.24411 · External reference
10.1007/s12010-011-9201-7
10.1007/s12010-011-9201-7 · External reference
10.1128/aem.00828-10
10.1128/aem.00828-10 · External reference
10.1007/s00253-012-4012-5
10.1007/s00253-012-4012-5 · External reference
10.1371/journal.pone.0016228
10.1371/journal.pone.0016228 · External reference
10.1007/s12010-008-8431-9
10.1007/s12010-008-8431-9 · External reference
Engineering global regulator Hha of Escherichia coli to control biofilm dispersal
10.1111/j.1751-7915.2010.00220.x · 2010 · External reference
Controlling biofilm formation, prophage excision and cell death by rewiring global regulator H-NS of Escherichia coli
10.1111/j.1751-7915.2010.00164.x · 2010 · External reference
10.1073/pnas.1206346109
10.1073/pnas.1206346109 · External reference
Why high-error-rate random mutagenesis libraries are enriched in functional and improved proteins
10.1016/j.jmb.2005.05.023 · 2005 · External reference
10.1038/nature08187
10.1038/nature08187 · External reference
10.1126/science.1205822
10.1126/science.1205822 · External reference
10.1093/nar/gks455
10.1093/nar/gks455 · External reference
Manipulating replisome dynamics to enhance lambda Red-mediated multiplex genome engineering
2012 · External reference
Improving Lambda Red Genome Engineering in Escherichia coli via Rational Removal of Endogenous Nucleases
10.1371/journal.pone.0044638 · 2012 · External reference
10.1038/nmeth.1971
10.1038/nmeth.1971 · External reference
Rapid profiling of a microbial genome using mixtures of barcoded oligonucleotides
10.1038/nbt.1653 · 2010 · External reference
10.1073/pnas.1206299109
10.1073/pnas.1206299109 · External reference
From microbial differentiation to ribosome engineering
10.1271/bbb.70007 · 2007 · External reference
Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor A3(2)
10.1128/jb.178.24.7276-7284.1996 · 1996 · External reference
A novel method for improving Streptomyces coelicolor A3(2) for production of actinorhodin by introduction of rpsL (encoding ribosomal protein S12) mutations conferring resistance to streptomycin
10.7164/antibiotics.50.532 · 1997 · External reference
Resistance to paromomycin is conferred by rpsL mutations, accompanied by an enhanced antibiotic production in Streptomyces coelicolor A3(2)
10.7164/antibiotics.53.1424 · 2000 · External reference
Mutations in rsmG, encoding a 16S rRNA methyltransferase, result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2)
10.1128/jb.01776-06 · 2007 · External reference
Acquisition of certain streptomycin-resistant (str) mutations enhances antibiotic production in bacteria
10.1128/aac.42.8.2041 · 1998 · External reference
10.1128/aem.72.1.71-77.2006
10.1128/aem.72.1.71-77.2006 · External reference
10.1128/jb.184.14.3984-3991.2002
10.1128/jb.184.14.3984-3991.2002 · External reference
10.1074/jbc.m309925200
10.1074/jbc.m309925200 · External reference
Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12
10.1038/nbt.1538 · 2009 · External reference
Streptomycin-resistant (rpsL) or rifampicin-resistant (rpoB) mutation in Pseudomonas putida KH146-2 confers enhanced tolerance to organic chemicals
10.1046/j.1462-2920.2002.00348.x · 2002 · External reference
Novel approach for improving the productivity of antibiotic-producing strains by inducing combined resistant mutations
10.1128/aem.67.4.1885-1892.2001 · 2001 · External reference
Innovative approach for improvement of an antibiotic-overproducing industrial strain of Streptomyces albus
10.1128/aem.69.11.6412-6417.2003 · 2003 · External reference
Genome shuffling leads to rapid phenotypic improvement in bacteria
10.1038/415644a · 2002 · External reference
Protoplast fusion: a tool for intergeneric gene transfer in bacteria
10.1016/0734-9750(93)90041-k · 1993 · External reference
Genome shuffling of Lactobacillus for improved acid tolerance
10.1038/nbt0702-707 · 2002 · External reference
Genome shuffling improves degradation of the anthropogenic pesticide pentachlorophenol by Sphingobium chlorophenolicum ATCC 39723
10.1128/aem.70.4.2391-2397.2004 · 2004 · External reference
Novel Escherichia coli hybrids with enhanced butanol tolerance
10.1007/s10529-010-0247-3 · 2010 · External reference
Improved ethanol production by a xylose-fermenting recombinant yeast strain constructed through a modified genome shuffling method
10.1186/1754-6834-5-46 · 2012 · External reference
Visualization of protoplast fusion and quantitation of recombination in fused protoplasts of auxotrophic strains of Escherichia coli
10.1016/j.ymben.2004.09.002 · 2005 · External reference
10.1016/j.ymben.2012.07.004
10.1016/j.ymben.2012.07.004 · External reference
10.1093/nar/25.6.1203
10.1093/nar/25.6.1203 · External reference
Global transcription machinery engineering: a new approach for improving cellular phenotype
10.1016/j.ymben.2006.12.002 · 2007 · External reference
Genome shuffling improves degradation of the anthropogenic pesticide pentachlorophenol by Sphingobium chlorophenolicum ATCC 39723
10.1128/aem.70.4.2391-2397.2004 · 2004 · External reference
