Research graph
References from Engineering human myelin microphysiological systems for testing patient treatment response in multiple sclerosis. Local targets link to admitted publications; unresolved targets remain external evidence.
Autoimmune associations in multiple sclerosis
10.1038/nrneurol.2010.147 · 2010 · External reference
10.1016/s0092-8674(00)81107-1
10.1016/s0092-8674(00)81107-1 · External reference
10.1101/cshperspect.a029025
10.1101/cshperspect.a029025 · External reference
Targeting microglia and macrophages: a potential treatment strategy for multiple sclerosis
10.3389/fphar.2019.00286 · 2019 · External reference
10.1093/intimm/12.12.1641
10.1093/intimm/12.12.1641 · External reference
10.1001/jama.2020.26858
10.1001/jama.2020.26858 · External reference
MS patients report excellent compliance with oral prednisone for acute relapses
10.1017/s0317167100013500 · 2012 · External reference
Predictors of response to multiple sclerosis therapeutics in individual patients
10.1007/s40265-016-0639-3 · 2016 · External reference
10.1007/s40263-013-0042-5
10.1007/s40263-013-0042-5 · External reference
Clinical outcomes of escalation vs early intensive disease-modifying therapy in patients with multiple sclerosis
10.1001/jamaneurol.2018.4905 · 2019 · External reference
Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study
10.1016/s1474-4422(20)30067-3 · 2020 · External reference
10.1001/jama.2018.20588
10.1001/jama.2018.20588 · External reference
10.1038/nature12517
10.1038/nature12517 · External reference
Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
10.1038/nmeth.3415 · 2015 · External reference
10.1016/j.stem.2019.08.002
10.1016/j.stem.2019.08.002 · External reference
Established and emerging new approach methodologies in neuroscience
10.3389/fnins.2025.1696937 · 2025 · External reference
10.1038/nature22047
10.1038/nature22047 · External reference
10.1038/s41586-019-1654-9
10.1038/s41586-019-1654-9 · External reference
10.1126/sciadv.adu2708
10.1126/sciadv.adu2708 · External reference
10.1038/s41593-021-00923-4
10.1038/s41593-021-00923-4 · External reference
10.1242/bio.059845
10.1242/bio.059845 · External reference
10.1101/2024.06.20.597748
10.1101/2024.06.20.597748 · External reference
Human myelinated brain organoids with integrated microglia as a model for myelin repair and remyelinating therapies
10.1126/scitranslmed.adp7047 · 2025 · External reference
The physiology of foamy phagocytes in multiple sclerosis
2018 · External reference
The role of antigen presenting cells in multiple sclerosis
2011 · External reference
When encephalitogenic T cells collaborate with microglia in multiple sclerosis
10.1038/s41582-019-0253-6 · 2019 · External reference
10.1002/1521-4141(200203)32:3<606::aid-immu606>3.0.co;2-d
10.1002/1521-4141(200203)32:3<606::aid-immu606>3.0.co;2-d · External reference
10.3389/fimmu.2015.00539
10.3389/fimmu.2015.00539 · External reference
10.1002/ijc.27661
10.1002/ijc.27661 · External reference
10.1371/journal.pone.0008668
10.1371/journal.pone.0008668 · External reference
10.1073/pnas.96.21.12033
10.1073/pnas.96.21.12033 · External reference
The human T cell response to myelin oligodendrocyte glycoprotein: a multiple sclerosis family-based study
10.4049/jimmunol.168.11.5920 · 2002 · External reference
10.3389/fimmu.2020.00760
10.3389/fimmu.2020.00760 · External reference
10.1186/1742-2094-10-1
10.1186/1742-2094-10-1 · External reference
10.1186/1742-2094-8-85
10.1186/1742-2094-8-85 · External reference
10.1111/ene.12883
10.1111/ene.12883 · External reference
Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes
2019 · External reference
The diagnosis of multiple sclerosis and the various related demyelinating syndromes: a critical review
2014 · External reference
10.1016/j.clineuro.2004.02.004
10.1016/j.clineuro.2004.02.004 · External reference
10.1007/s11940-015-0354-5
10.1007/s11940-015-0354-5 · External reference
10.1097/wco.0000000000000937
10.1097/wco.0000000000000937 · External reference
10.1177/2055217320946784
10.1177/2055217320946784 · External reference
10.1016/j.autrev.2015.07.014
10.1016/j.autrev.2015.07.014 · External reference
A blood-based metabolomics test to distinguish relapsing–remitting and secondary progressive multiple sclerosis: addressing practical considerations for clinical application
2020 · External reference
10.1212/nxi.0000000000000732
10.1212/nxi.0000000000000732 · External reference
Multi-parameter immune profiling of peripheral blood mononuclear cells by multiplexed single-cell mass cytometry in patients with early multiple sclerosis
2019 · External reference
10.1046/j.1365-2249.1999.00816.x
10.1046/j.1365-2249.1999.00816.x · External reference
Detection of altered T helper 1 and T helper 2 cytokine production by peripheral blood mononuclear cells in patients with multiple sclerosis utilizing intracellular cytokine detection by flow cytometry and surface marker analysis
10.1128/cdli.3.4.411-416.1996 · 1996 · External reference
10.1001/archneur.1992.00530270079022
10.1001/archneur.1992.00530270079022 · External reference
10.1038/icb.2014.15
10.1038/icb.2014.15 · External reference
10.1016/j.jneuroim.2003.10.035
10.1016/j.jneuroim.2003.10.035 · External reference
10.4110/in.2018.18.e5
10.4110/in.2018.18.e5 · External reference
10.1189/jlb.0413207
10.1189/jlb.0413207 · External reference
10.1523/jneurosci.3241-13.2013
10.1523/jneurosci.3241-13.2013 · External reference
10.1007/s00401-015-1452-x
10.1007/s00401-015-1452-x · External reference
10.1007/s11481-018-09832-z
10.1007/s11481-018-09832-z · External reference
10.1007/s40263-021-00822-z
10.1007/s40263-021-00822-z · External reference
10.1189/jlb.0804477
10.1189/jlb.0804477 · External reference
10.1016/s0167-5699(99)01512-1
10.1016/s0167-5699(99)01512-1 · External reference
10.1002/ana.21939
10.1002/ana.21939 · External reference
10.3390/cells8101236
10.3390/cells8101236 · External reference
10.1007/s00401-013-1112-y
10.1007/s00401-013-1112-y · External reference
10.1007/s12017-019-08551-9
10.1007/s12017-019-08551-9 · External reference
10.1039/d1lc00030f
10.1039/d1lc00030f · External reference
10.1039/d1lc00145k
10.1039/d1lc00145k · External reference
10.1001/archneur.1992.00530270079022
10.1001/archneur.1992.00530270079022 · ExternalCitation · doi-reference
10.1001/jama.2018.20588
10.1001/jama.2018.20588 · ExternalCitation · doi-reference
10.1001/jama.2020.26858
10.1001/jama.2020.26858 · ExternalCitation · doi-reference
Clinical outcomes of escalation vs early intensive disease-modifying therapy in patients with multiple sclerosis
10.1001/jamaneurol.2018.4905 · ExternalCitation · doi-reference
10.1002/1521-4141(200203)32:3<606::aid-immu606>3.0.co;2-d
10.1002/1521-4141(200203)32:3<606::aid-immu606>3.0.co;2-d · ExternalCitation · doi-reference
10.1002/ana.21939
10.1002/ana.21939 · ExternalCitation · doi-reference
10.1002/ijc.27661
10.1002/ijc.27661 · ExternalCitation · doi-reference
10.1007/s00401-013-1112-y
10.1007/s00401-013-1112-y · ExternalCitation · doi-reference
10.1007/s00401-015-1452-x
10.1007/s00401-015-1452-x · ExternalCitation · doi-reference
10.1007/s11481-018-09832-z
10.1007/s11481-018-09832-z · ExternalCitation · doi-reference
10.1007/s11940-015-0354-5
10.1007/s11940-015-0354-5 · ExternalCitation · doi-reference
10.1007/s12017-019-08551-9
10.1007/s12017-019-08551-9 · ExternalCitation · doi-reference
10.1007/s40263-013-0042-5
10.1007/s40263-013-0042-5 · ExternalCitation · doi-reference
10.1007/s40263-021-00822-z
10.1007/s40263-021-00822-z · ExternalCitation · doi-reference
Predictors of response to multiple sclerosis therapeutics in individual patients
10.1007/s40265-016-0639-3 · ExternalCitation · doi-reference
10.1016/j.autrev.2015.07.014
10.1016/j.autrev.2015.07.014 · ExternalCitation · doi-reference
10.1016/j.clineuro.2004.02.004
10.1016/j.clineuro.2004.02.004 · ExternalCitation · doi-reference
10.1016/j.jneuroim.2003.10.035
10.1016/j.jneuroim.2003.10.035 · ExternalCitation · doi-reference
10.1016/j.stem.2019.08.002
10.1016/j.stem.2019.08.002 · ExternalCitation · doi-reference
10.1016/s0092-8674(00)81107-1
10.1016/s0092-8674(00)81107-1 · ExternalCitation · doi-reference
10.1016/s0167-5699(99)01512-1
10.1016/s0167-5699(99)01512-1 · ExternalCitation · doi-reference
Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study
10.1016/s1474-4422(20)30067-3 · ExternalCitation · doi-reference
MS patients report excellent compliance with oral prednisone for acute relapses
10.1017/s0317167100013500 · ExternalCitation · doi-reference
10.1038/icb.2014.15
10.1038/icb.2014.15 · ExternalCitation · doi-reference
10.1038/nature12517
10.1038/nature12517 · ExternalCitation · doi-reference
10.1038/nature22047
10.1038/nature22047 · ExternalCitation · doi-reference
Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
10.1038/nmeth.3415 · ExternalCitation · doi-reference
Autoimmune associations in multiple sclerosis
10.1038/nrneurol.2010.147 · ExternalCitation · doi-reference
When encephalitogenic T cells collaborate with microglia in multiple sclerosis
10.1038/s41582-019-0253-6 · ExternalCitation · doi-reference
10.1038/s41586-019-1654-9
10.1038/s41586-019-1654-9 · ExternalCitation · doi-reference
10.1038/s41593-021-00923-4
10.1038/s41593-021-00923-4 · ExternalCitation · doi-reference
10.1039/d1lc00030f
10.1039/d1lc00030f · ExternalCitation · doi-reference
10.1039/d1lc00145k
10.1039/d1lc00145k · ExternalCitation · doi-reference
10.1046/j.1365-2249.1999.00816.x
10.1046/j.1365-2249.1999.00816.x · ExternalCitation · doi-reference
10.1073/pnas.96.21.12033
10.1073/pnas.96.21.12033 · ExternalCitation · doi-reference
10.1093/intimm/12.12.1641
10.1093/intimm/12.12.1641 · ExternalCitation · doi-reference
10.1097/wco.0000000000000937
10.1097/wco.0000000000000937 · ExternalCitation · doi-reference
10.1101/2024.06.20.597748
10.1101/2024.06.20.597748 · ExternalCitation · doi-reference
10.1101/cshperspect.a029025
10.1101/cshperspect.a029025 · ExternalCitation · doi-reference
10.1111/ene.12883
10.1111/ene.12883 · ExternalCitation · doi-reference
10.1126/sciadv.adu2708
10.1126/sciadv.adu2708 · ExternalCitation · doi-reference
Human myelinated brain organoids with integrated microglia as a model for myelin repair and remyelinating therapies
10.1126/scitranslmed.adp7047 · ExternalCitation · doi-reference
Detection of altered T helper 1 and T helper 2 cytokine production by peripheral blood mononuclear cells in patients with multiple sclerosis utilizing intracellular cytokine detection by flow cytometry and surface marker analysis
10.1128/cdli.3.4.411-416.1996 · ExternalCitation · doi-reference
10.1177/2055217320946784
10.1177/2055217320946784 · ExternalCitation · doi-reference
10.1186/1742-2094-10-1
10.1186/1742-2094-10-1 · ExternalCitation · doi-reference
10.1186/1742-2094-8-85
10.1186/1742-2094-8-85 · ExternalCitation · doi-reference
10.1189/jlb.0413207
10.1189/jlb.0413207 · ExternalCitation · doi-reference
10.1189/jlb.0804477
10.1189/jlb.0804477 · ExternalCitation · doi-reference
10.1212/nxi.0000000000000732
10.1212/nxi.0000000000000732 · ExternalCitation · doi-reference
10.1242/bio.059845
10.1242/bio.059845 · ExternalCitation · doi-reference
10.1371/journal.pone.0008668
10.1371/journal.pone.0008668 · ExternalCitation · doi-reference
10.1523/jneurosci.3241-13.2013
10.1523/jneurosci.3241-13.2013 · ExternalCitation · doi-reference
10.3389/fimmu.2015.00539
10.3389/fimmu.2015.00539 · ExternalCitation · doi-reference
10.3389/fimmu.2020.00760
10.3389/fimmu.2020.00760 · ExternalCitation · doi-reference
Established and emerging new approach methodologies in neuroscience
10.3389/fnins.2025.1696937 · ExternalCitation · doi-reference
Targeting microglia and macrophages: a potential treatment strategy for multiple sclerosis
10.3389/fphar.2019.00286 · ExternalCitation · doi-reference
10.3390/cells8101236
10.3390/cells8101236 · ExternalCitation · doi-reference
The human T cell response to myelin oligodendrocyte glycoprotein: a multiple sclerosis family-based study
10.4049/jimmunol.168.11.5920 · ExternalCitation · doi-reference
10.4110/in.2018.18.e5
10.4110/in.2018.18.e5 · ExternalCitation · doi-reference
