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References from Exposure to a mixture of long-chain per- and polyfluoroalkyl substances (PFAS) disrupts ovarian follicle development, ovulation, and luteinization in female mice. Local targets link to admitted publications; unresolved targets remain external evidence.
An overview of the uses of per- and polyfluoroalkyl substances (PFAS)
10.1039/d0em00291g · 2020 · External reference
10.3390/molecules30224415
10.3390/molecules30224415 · External reference
10.1007/s00449-026-03317-7
10.1007/s00449-026-03317-7 · External reference
Effects of Per- and Polyfluoroalkylated Substances on Female Reproduction
10.3390/toxics12070455 · 2024 · External reference
10.1289/ehp.10009
10.1289/ehp.10009 · External reference
10.1038/s41598-025-16395-6
10.1038/s41598-025-16395-6 · External reference
10.1016/j.envint.2013.06.004
10.1016/j.envint.2013.06.004 · External reference
Unresolved reference
External reference
10.1016/j.envint.2025.109382
10.1016/j.envint.2025.109382 · External reference
10.1016/j.envres.2025.120916
10.1016/j.envres.2025.120916 · External reference
Serum concentrations of legacy, alternative, and precursor per- and polyfluoroalkyl substances: a descriptive analysis of adult female participants in the MIREC-ENDO study
10.1186/s12940-024-01085-z · 2024 · External reference
10.1016/j.envint.2020.106123
10.1016/j.envint.2020.106123 · External reference
Assessing the Impact of Serum Per- and Polyfluoroalkyl Substance Concentrations on Immune Function in an Industrialized Region of China
10.1021/envhealth.4c00224 · 2025 · External reference
Occupational exposure to per- and polyfluoroalkyl substances: a scope review of the literature from 1980-2021
10.1038/s41370-023-00536-y · 2023 · External reference
High serum perfluorooctanoic acid (PFOA) concentrations and interstitial lung disease in former and current workers in a fluorochemical company
10.2486/indhealth.2025-0009 · 2025 · External reference
10.1021/acs.est.3c06499
10.1021/acs.est.3c06499 · External reference
10.1038/s41598-017-07359-6
10.1038/s41598-017-07359-6 · External reference
Per- and polyfluoroalkyl substances (PFAS) exposure in women seeking in vitro fertilization-embryo transfer treatment (IVF-ET) in China: Blood-follicular transfer and associations with IVF-ET outcomes
2022 · External reference
Perfluorinated alkyl acids in the serum and follicular fluid of UK women with and without polycystic ovarian syndrome undergoing fertility treatment and associations with hormonal and metabolic parameters
10.1016/j.ijheh.2018.07.009 · 2018 · External reference
10.1016/j.envint.2020.105686
10.1016/j.envint.2020.105686 · External reference
10.1016/j.envpol.2023.121348
10.1016/j.envpol.2023.121348 · External reference
10.1016/j.tox.2026.154509
10.1016/j.tox.2026.154509 · External reference
10.1038/s41370-024-00742-2
10.1038/s41370-024-00742-2 · External reference
10.1016/j.envres.2020.110690
10.1016/j.envres.2020.110690 · External reference
Childhood PFAS exposure and immunotoxicity: a systematic review and meta-analysis of human studies
10.1186/s13643-024-02596-z · 2024 · External reference
Per and polyfluoroalkyl substances affect thyroid hormones for people with a history of exposure from drinking water
10.1038/s41598-025-91977-y · 2025 · External reference
Associations of perfluoroalkyl substances (PFAS) with lipid and lipoprotein profiles
10.1038/s41370-023-00545-x · 2023 · External reference
10.1016/j.envpol.2026.128063
10.1016/j.envpol.2026.128063 · External reference
Use of Tox21 screening data to profile PFAS bioactivities on nuclear receptors, cellular stress pathways, and cytochrome p450 enzymes
10.1016/j.jhazmat.2024.134642 · 2024 · External reference
10.3390/ijms25158241
10.3390/ijms25158241 · External reference
Per- and Polyfluoroalkyl Substances (PFAS) Affect Female Reproductive Health: Epidemiological Evidence and Underlying Mechanisms
10.3390/toxics12090678 · 2024 · External reference
10.1016/j.envres.2024.118485
10.1016/j.envres.2024.118485 · External reference
10.1016/j.reprotox.2025.109086
10.1016/j.reprotox.2025.109086 · External reference
Association between novel per-and poly-fluoroalkyl substances and premature ovarian insufficiency: a case-control study
10.1093/hropen/hoaf044 · 2025 · External reference
10.1016/j.reprotox.2026.109207
10.1016/j.reprotox.2026.109207 · External reference
Plasma Perfluoroalkyl and Polyfluoroalkyl Substances Concentration and Menstrual Cycle Characteristics in Preconception Women
10.1289/ehp1203 · 2017 · External reference
10.1016/j.scitotenv.2024.175313
10.1016/j.scitotenv.2024.175313 · External reference
10.1016/j.ecoenv.2024.116251
10.1016/j.ecoenv.2024.116251 · External reference
10.1016/j.envres.2022.114718
10.1016/j.envres.2022.114718 · External reference
10.1016/j.envpol.2024.124474
10.1016/j.envpol.2024.124474 · External reference
Impact of Perfluorooctane Sulfonate on Reproductive Ability of Female Mice through Suppression of Estrogen Receptor alpha-Activated Kisspeptin Neurons
10.1093/toxsci/kfy167 · 2018 · External reference
Exposure to Long-and Short-Chain Per- and Polyfluoroalkyl Substances in Mice and Ovarian-Related Outcomes: An in Vivo and in Vitro Study
10.1289/ehp14876 · 2025 · External reference
Prenatal Exposure to PFOA Induces Ovarian Function Impairment via the Disruption of the PPARgamma/ANGPTL4 Pathway
10.1021/envhealth.5c00576 · 2026 · External reference
Potential Effects of Prepubertal Exposure to Perfluorooctane Sulfonic Acid on the First Wave of Folliculogenesis in Young CD-1 Mice
10.1002/bdr2.70052 · 2026 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
Unresolved reference
External reference
Unresolved reference
External reference
10.15620/cdc:106273
10.15620/cdc:106273 · External reference
10.1007/s00420-007-0213-0
10.1007/s00420-007-0213-0 · External reference
10.1097/01.jom.0000052958.59271.10
10.1097/01.jom.0000052958.59271.10 · External reference
10.1097/00043764-199909000-00012
10.1097/00043764-199909000-00012 · External reference
10.1093/biolre/ioad009
10.1093/biolre/ioad009 · External reference
10.1210/endocr/bqab014
10.1210/endocr/bqab014 · External reference
10.1210/en.2013-1502
10.1210/en.2013-1502 · External reference
10.1016/j.emcon.2024.100438
10.1016/j.emcon.2024.100438 · External reference
10.1093/humrep/det390
10.1093/humrep/det390 · External reference
Per-and Polyfluoroalkyl Substances and Hormone Levels During the Menopausal Transition
10.1210/clinem/dgab476 · 2021 · External reference
10.1186/s12302-021-00508-9
10.1186/s12302-021-00508-9 · External reference
10.3390/life15121923
10.3390/life15121923 · External reference
10.1016/j.envpol.2023.121707
10.1016/j.envpol.2023.121707 · External reference
10.1016/j.scitotenv.2023.164353
10.1016/j.scitotenv.2023.164353 · External reference
10.1016/j.envint.2021.106408
10.1016/j.envint.2021.106408 · External reference
10.1016/j.envpol.2023.122214
10.1016/j.envpol.2023.122214 · External reference
10.1210/er.2018-00075
10.1210/er.2018-00075 · External reference
10.1016/j.scitotenv.2022.156602
10.1016/j.scitotenv.2022.156602 · External reference
Underestimated burden of per- and polyfluoroalkyl substances in global surface waters and groundwaters
10.1038/s41561-024-01402-8 · 2024 · External reference
10.1038/srep38039
10.1038/srep38039 · External reference
Per and polyfluoroalkyl substances (PFAS) blood levels after contamination of a community water supply and comparison with 2013–2014 NHANES
2018 · External reference
10.1016/j.envint.2017.10.026
10.1016/j.envint.2017.10.026 · External reference
10.1016/j.taap.2025.117336
10.1016/j.taap.2025.117336 · External reference
Potential Effects of Prepubertal Exposure to Perfluorooctane Sulfonic Acid on the First Wave of Folliculogenesis in Young CD-1 Mice
10.1002/bdr2.70052 · ExternalCitation · doi-reference
10.1007/s00420-007-0213-0
10.1007/s00420-007-0213-0 · ExternalCitation · doi-reference
10.1007/s00449-026-03317-7
10.1007/s00449-026-03317-7 · ExternalCitation · doi-reference
10.1016/j.ecoenv.2024.116251
10.1016/j.ecoenv.2024.116251 · ExternalCitation · doi-reference
10.1016/j.emcon.2024.100438
10.1016/j.emcon.2024.100438 · ExternalCitation · doi-reference
10.1016/j.envint.2013.06.004
10.1016/j.envint.2013.06.004 · ExternalCitation · doi-reference
10.1016/j.envint.2017.10.026
10.1016/j.envint.2017.10.026 · ExternalCitation · doi-reference
10.1016/j.envint.2020.105686
10.1016/j.envint.2020.105686 · ExternalCitation · doi-reference
10.1016/j.envint.2020.106123
10.1016/j.envint.2020.106123 · ExternalCitation · doi-reference
10.1016/j.envint.2021.106408
10.1016/j.envint.2021.106408 · ExternalCitation · doi-reference
10.1016/j.envint.2025.109382
10.1016/j.envint.2025.109382 · ExternalCitation · doi-reference
10.1016/j.envpol.2023.121348
10.1016/j.envpol.2023.121348 · ExternalCitation · doi-reference
10.1016/j.envpol.2023.121707
10.1016/j.envpol.2023.121707 · ExternalCitation · doi-reference
10.1016/j.envpol.2023.122214
10.1016/j.envpol.2023.122214 · ExternalCitation · doi-reference
10.1016/j.envpol.2024.124474
10.1016/j.envpol.2024.124474 · ExternalCitation · doi-reference
10.1016/j.envpol.2026.128063
10.1016/j.envpol.2026.128063 · ExternalCitation · doi-reference
10.1016/j.envres.2020.110690
10.1016/j.envres.2020.110690 · ExternalCitation · doi-reference
10.1016/j.envres.2022.114718
10.1016/j.envres.2022.114718 · ExternalCitation · doi-reference
10.1016/j.envres.2024.118485
10.1016/j.envres.2024.118485 · ExternalCitation · doi-reference
10.1016/j.envres.2025.120916
10.1016/j.envres.2025.120916 · ExternalCitation · doi-reference
Perfluorinated alkyl acids in the serum and follicular fluid of UK women with and without polycystic ovarian syndrome undergoing fertility treatment and associations with hormonal and metabolic parameters
10.1016/j.ijheh.2018.07.009 · ExternalCitation · doi-reference
Use of Tox21 screening data to profile PFAS bioactivities on nuclear receptors, cellular stress pathways, and cytochrome p450 enzymes
10.1016/j.jhazmat.2024.134642 · ExternalCitation · doi-reference
10.1016/j.reprotox.2025.109086
10.1016/j.reprotox.2025.109086 · ExternalCitation · doi-reference
10.1016/j.reprotox.2026.109207
10.1016/j.reprotox.2026.109207 · ExternalCitation · doi-reference
10.1016/j.scitotenv.2022.156602
10.1016/j.scitotenv.2022.156602 · ExternalCitation · doi-reference
10.1016/j.scitotenv.2023.164353
10.1016/j.scitotenv.2023.164353 · ExternalCitation · doi-reference
10.1016/j.scitotenv.2024.175313
10.1016/j.scitotenv.2024.175313 · ExternalCitation · doi-reference
10.1016/j.taap.2025.117336
10.1016/j.taap.2025.117336 · ExternalCitation · doi-reference
10.1016/j.tox.2026.154509
10.1016/j.tox.2026.154509 · ExternalCitation · doi-reference
10.1021/acs.est.3c06499
10.1021/acs.est.3c06499 · ExternalCitation · doi-reference
Assessing the Impact of Serum Per- and Polyfluoroalkyl Substance Concentrations on Immune Function in an Industrialized Region of China
10.1021/envhealth.4c00224 · ExternalCitation · doi-reference
Prenatal Exposure to PFOA Induces Ovarian Function Impairment via the Disruption of the PPARgamma/ANGPTL4 Pathway
10.1021/envhealth.5c00576 · ExternalCitation · doi-reference
Occupational exposure to per- and polyfluoroalkyl substances: a scope review of the literature from 1980-2021
10.1038/s41370-023-00536-y · ExternalCitation · doi-reference
Associations of perfluoroalkyl substances (PFAS) with lipid and lipoprotein profiles
10.1038/s41370-023-00545-x · ExternalCitation · doi-reference
10.1038/s41370-024-00742-2
10.1038/s41370-024-00742-2 · ExternalCitation · doi-reference
Underestimated burden of per- and polyfluoroalkyl substances in global surface waters and groundwaters
10.1038/s41561-024-01402-8 · ExternalCitation · doi-reference
10.1038/s41598-017-07359-6
10.1038/s41598-017-07359-6 · ExternalCitation · doi-reference
10.1038/s41598-025-16395-6
10.1038/s41598-025-16395-6 · ExternalCitation · doi-reference
Per and polyfluoroalkyl substances affect thyroid hormones for people with a history of exposure from drinking water
10.1038/s41598-025-91977-y · ExternalCitation · doi-reference
10.1038/srep38039
10.1038/srep38039 · ExternalCitation · doi-reference
An overview of the uses of per- and polyfluoroalkyl substances (PFAS)
10.1039/d0em00291g · ExternalCitation · doi-reference
10.1093/biolre/ioad009
10.1093/biolre/ioad009 · ExternalCitation · doi-reference
Association between novel per-and poly-fluoroalkyl substances and premature ovarian insufficiency: a case-control study
10.1093/hropen/hoaf044 · ExternalCitation · doi-reference
10.1093/humrep/det390
10.1093/humrep/det390 · ExternalCitation · doi-reference
Impact of Perfluorooctane Sulfonate on Reproductive Ability of Female Mice through Suppression of Estrogen Receptor alpha-Activated Kisspeptin Neurons
10.1093/toxsci/kfy167 · ExternalCitation · doi-reference
10.1097/00043764-199909000-00012
10.1097/00043764-199909000-00012 · ExternalCitation · doi-reference
10.1097/01.jom.0000052958.59271.10
10.1097/01.jom.0000052958.59271.10 · ExternalCitation · doi-reference
10.1186/s12302-021-00508-9
10.1186/s12302-021-00508-9 · ExternalCitation · doi-reference
Serum concentrations of legacy, alternative, and precursor per- and polyfluoroalkyl substances: a descriptive analysis of adult female participants in the MIREC-ENDO study
10.1186/s12940-024-01085-z · ExternalCitation · doi-reference
Childhood PFAS exposure and immunotoxicity: a systematic review and meta-analysis of human studies
10.1186/s13643-024-02596-z · ExternalCitation · doi-reference
Per-and Polyfluoroalkyl Substances and Hormone Levels During the Menopausal Transition
10.1210/clinem/dgab476 · ExternalCitation · doi-reference
10.1210/en.2013-1502
10.1210/en.2013-1502 · ExternalCitation · doi-reference
10.1210/endocr/bqab014
10.1210/endocr/bqab014 · ExternalCitation · doi-reference
10.1210/er.2018-00075
10.1210/er.2018-00075 · ExternalCitation · doi-reference
10.1289/ehp.10009
10.1289/ehp.10009 · ExternalCitation · doi-reference
Plasma Perfluoroalkyl and Polyfluoroalkyl Substances Concentration and Menstrual Cycle Characteristics in Preconception Women
10.1289/ehp1203 · ExternalCitation · doi-reference
Exposure to Long-and Short-Chain Per- and Polyfluoroalkyl Substances in Mice and Ovarian-Related Outcomes: An in Vivo and in Vitro Study
10.1289/ehp14876 · ExternalCitation · doi-reference
10.15620/cdc:106273
10.15620/cdc:106273 · ExternalCitation · doi-reference
High serum perfluorooctanoic acid (PFOA) concentrations and interstitial lung disease in former and current workers in a fluorochemical company
10.2486/indhealth.2025-0009 · ExternalCitation · doi-reference
10.3390/ijms25158241
10.3390/ijms25158241 · ExternalCitation · doi-reference
10.3390/life15121923
10.3390/life15121923 · ExternalCitation · doi-reference
10.3390/molecules30224415
10.3390/molecules30224415 · ExternalCitation · doi-reference
Effects of Per- and Polyfluoroalkylated Substances on Female Reproduction
10.3390/toxics12070455 · ExternalCitation · doi-reference
Per- and Polyfluoroalkyl Substances (PFAS) Affect Female Reproductive Health: Epidemiological Evidence and Underlying Mechanisms
10.3390/toxics12090678 · ExternalCitation · doi-reference
