Research graph
References from Charged residues, not aromatics, are the universal topological hubs of intrinsically disordered proteins. Local targets link to admitted publications; unresolved targets remain external evidence.
Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept
10.1146/annurev.biophys.37.032807.125924 · 2008 · External reference
10.1038/nrm1589
10.1038/nrm1589 · External reference
10.1038/s41580-023-00673-0
10.1038/s41580-023-00673-0 · External reference
10.1016/j.tcb.2018.02.004
10.1016/j.tcb.2018.02.004 · External reference
10.1126/science.1065103
10.1126/science.1065103 · External reference
10.1016/j.cell.2018.06.006
10.1016/j.cell.2018.06.006 · External reference
10.1016/j.molcel.2022.05.018
10.1016/j.molcel.2022.05.018 · External reference
10.1146/annurev-biophys-121219-081629
10.1146/annurev-biophys-121219-081629 · External reference
Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
2020 · External reference
10.1371/journal.pbio.3000327
10.1371/journal.pbio.3000327 · External reference
10.1038/s41467-023-41274-x
10.1038/s41467-023-41274-x · External reference
Unresolved reference
External reference
10.1080/0022250x.2001.9990249
10.1080/0022250x.2001.9990249 · External reference
10.12688/openreseurope.14967.2
10.12688/openreseurope.14967.2 · External reference
Quantitative prediction of ensemble dynamics, shapes and contact propensities of intrinsically disordered proteins
10.1371/journal.pcbi.1010036 · 2022 · External reference
Physics-driven coarse-grained model for biomolecular phase separation with near-quantitative accuracy
10.1038/s43588-021-00155-3 · 2021 · External reference
10.1103/physrevlett.89.208701
10.1103/physrevlett.89.208701 · External reference
10.1073/pnas.2000223117
10.1073/pnas.2000223117 · External reference
10.1093/nar/gkac386
10.1093/nar/gkac386 · External reference
10.1038/s41467-024-50812-0
10.1038/s41467-024-50812-0 · External reference
10.1038/nature24039
10.1038/nature24039 · External reference
10.1016/0022-2836(91)90721-h
10.1016/0022-2836(91)90721-h · External reference
Distinct Functions of cis and trans Phosphorylated Tau in Alzheimer’s Disease and their Therapeutic Implications
10.2174/1566524011313070001 · 2013 · External reference
10.1016/j.tibs.2011.07.001
10.1016/j.tibs.2011.07.001 · External reference
10.1007/s10858-007-9166-6
10.1007/s10858-007-9166-6 · External reference
10.4161/idp.24360
10.4161/idp.24360 · External reference
10.31083/j.fbl2806127
10.31083/j.fbl2806127 · External reference
10.1101/2025.10.01.679751
10.1101/2025.10.01.679751 · External reference
Unresolved reference
External reference
10.1073/pnas.2111696118
10.1073/pnas.2111696118 · External reference
10.1007/s10858-007-9166-6
10.1007/s10858-007-9166-6 · ExternalCitation · doi-reference
10.1016/0022-2836(91)90721-h
10.1016/0022-2836(91)90721-h · ExternalCitation · doi-reference
10.1016/j.cell.2018.06.006
10.1016/j.cell.2018.06.006 · ExternalCitation · doi-reference
10.1016/j.molcel.2022.05.018
10.1016/j.molcel.2022.05.018 · ExternalCitation · doi-reference
10.1016/j.tcb.2018.02.004
10.1016/j.tcb.2018.02.004 · ExternalCitation · doi-reference
10.1016/j.tibs.2011.07.001
10.1016/j.tibs.2011.07.001 · ExternalCitation · doi-reference
10.1038/nature24039
10.1038/nature24039 · ExternalCitation · doi-reference
10.1038/nrm1589
10.1038/nrm1589 · ExternalCitation · doi-reference
10.1038/s41467-023-41274-x
10.1038/s41467-023-41274-x · ExternalCitation · doi-reference
10.1038/s41467-024-50812-0
10.1038/s41467-024-50812-0 · ExternalCitation · doi-reference
10.1038/s41580-023-00673-0
10.1038/s41580-023-00673-0 · ExternalCitation · doi-reference
Physics-driven coarse-grained model for biomolecular phase separation with near-quantitative accuracy
10.1038/s43588-021-00155-3 · ExternalCitation · doi-reference
10.1073/pnas.2000223117
10.1073/pnas.2000223117 · ExternalCitation · doi-reference
10.1073/pnas.2111696118
10.1073/pnas.2111696118 · ExternalCitation · doi-reference
10.1080/0022250x.2001.9990249
10.1080/0022250x.2001.9990249 · ExternalCitation · doi-reference
10.1093/nar/gkac386
10.1093/nar/gkac386 · ExternalCitation · doi-reference
10.1101/2025.10.01.679751
10.1101/2025.10.01.679751 · ExternalCitation · doi-reference
10.1103/physrevlett.89.208701
10.1103/physrevlett.89.208701 · ExternalCitation · doi-reference
10.1126/science.1065103
10.1126/science.1065103 · ExternalCitation · doi-reference
10.1146/annurev-biophys-121219-081629
10.1146/annurev-biophys-121219-081629 · ExternalCitation · doi-reference
Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept
10.1146/annurev.biophys.37.032807.125924 · ExternalCitation · doi-reference
10.12688/openreseurope.14967.2
10.12688/openreseurope.14967.2 · ExternalCitation · doi-reference
10.1371/journal.pbio.3000327
10.1371/journal.pbio.3000327 · ExternalCitation · doi-reference
Quantitative prediction of ensemble dynamics, shapes and contact propensities of intrinsically disordered proteins
10.1371/journal.pcbi.1010036 · ExternalCitation · doi-reference
Distinct Functions of cis and trans Phosphorylated Tau in Alzheimer’s Disease and their Therapeutic Implications
10.2174/1566524011313070001 · ExternalCitation · doi-reference
10.31083/j.fbl2806127
10.31083/j.fbl2806127 · ExternalCitation · doi-reference
10.4161/idp.24360
10.4161/idp.24360 · ExternalCitation · doi-reference
