Research graph
References from Dynamic Responses to an Inflammatory Challenge Distinguish Metabolic Health Across Lean and Obese Individuals. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1136/bmjdrc-2025-005118
10.1136/bmjdrc-2025-005118 · External reference
TREM1 signaling amplifies neutrophil-mediated inflammation in inflammatory bowel disease
10.1038/s41467-026-75319-8 · 2026 · External reference
State of Cutaneous Microcirculation in Patients with Obesity
10.36740/wlek202109103 · 2021 · External reference
10.1038/ijo.2009.199
10.1038/ijo.2009.199 · External reference
10.1111/joim.12384
10.1111/joim.12384 · External reference
Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes
10.1016/j.molmet.2015.04.002 · 2015 · External reference
10.3389/fimmu.2017.00254
10.3389/fimmu.2017.00254 · External reference
10.1210/endrev/bnaa004
10.1210/endrev/bnaa004 · External reference
An overview of obesity-related complications: The epidemiological evidence linking body weight and other markers of obesity to adverse health outcomes. Diabetes
10.1111/dom.16263 · 2025 · External reference
10.1146/annurev-nutr-071816-064800
10.1146/annurev-nutr-071816-064800 · External reference
Metalloproteinases and Wound Healing
10.1089/wound.2014.0581 · 2015 · External reference
10.1038/nrm1619
10.1038/nrm1619 · External reference
Insights on the role of the chemokine CCL8 in pathology
10.1016/j.cellsig.2025.111951 · 2025 · External reference
Joint effect of BMI and metabolic status on mortality among adults: a population-based longitudinal study in United States
10.1038/s41598-024-53229-3 · 2024 · External reference
10.1042/ebc20200018
10.1042/ebc20200018 · External reference
10.1038/s41590-020-0646-0
10.1038/s41590-020-0646-0 · External reference
10.1159/000088261
10.1159/000088261 · External reference
10.1016/j.ajpath.2015.01.020
10.1016/j.ajpath.2015.01.020 · External reference
Different associations of adipokines in lean and healthy adults
2014 · External reference
Effects of interleukin-1 antagonism and corticosteroids on fibroblast growth factor-21 in patients with metabolic syndrome
10.1038/s41598-021-87207-w · 2021 · External reference
10.1111/iwj.70035
10.1111/iwj.70035 · External reference
10.1155/2012/476380
10.1155/2012/476380 · External reference
10.1016/j.diabres.2014.04.006
10.1016/j.diabres.2014.04.006 · External reference
Serum Tumor Necrosis Factor Alpha (TNF-alpha) Levels in Obese and Overweight Adults: Correlations With Metabolic Syndrome and Inflammatory Markers
2024 · External reference
High levels of LIGHT/TNFSF14 in patients with Prader-Willi syndrome
10.1007/s40618-023-02050-2 · 2023 · External reference
Mechanisms Involved in Childhood Obesity-Related Bone Fragility
10.3389/fendo.2019.00269 · 2019 · External reference
10.1002/jcp.22385
10.1002/jcp.22385 · External reference
10.1016/j.pharmthera.2020.107670
10.1016/j.pharmthera.2020.107670 · External reference
10.3109/03008207.2013.822865
10.3109/03008207.2013.822865 · External reference
10.1016/j.mvr.2011.01.002
10.1016/j.mvr.2011.01.002 · External reference
Atherosclerosis is a major human killer and non-resolving inflammation is a prime suspect
2021 · External reference
10.1038/s41591-019-0675-0
10.1038/s41591-019-0675-0 · External reference
10.1016/j.biocel.2007.10.024
10.1016/j.biocel.2007.10.024 · External reference
10.3389/fimmu.2022.861931
10.3389/fimmu.2022.861931 · External reference
10.1093/bioinformatics/btw313
10.1093/bioinformatics/btw313 · External reference
Tissue macrophages: origin, heterogenity, biological functions, diseases and therapeutic targets
10.1038/s41392-025-02124-y · 2025 · External reference
Tumor Necrosis Factor: A Master Regulator in Inflammation and Disease-Pathways, Implications, and Breakthrough Therapies
10.1177/10799907261418982 · 2026 · External reference
10.1007/s00125-016-4036-y
10.1007/s00125-016-4036-y · External reference
10.3389/fimmu.2022.876515
10.3389/fimmu.2022.876515 · External reference
Update on the epidermal differentiation complex
10.2741/4001 · 2012 · External reference
10.1007/s10238-024-01508-8
10.1007/s10238-024-01508-8 · External reference
Urokinase Plasminogen Activator Deficiency Delays the Development of Obesity and Metabolic Sequelae
2026 · External reference
10.1016/j.metabol.2018.11.009
10.1016/j.metabol.2018.11.009 · External reference
Metabolically healthy obese individuals present similar chronic inflammation level but less insulin-resistance than obese individuals with metabolic syndrome
10.1371/journal.pone.0190528 · 2017 · External reference
10.1111/acel.13583
10.1111/acel.13583 · External reference
Characterisation of leukocytes in a human skin blister model of acute inflammation and resolution
10.1371/journal.pone.0089375 · 2014 · External reference
10.1258/cvd.2012.012008
10.1258/cvd.2012.012008 · External reference
10.3389/fimmu.2020.00487
10.3389/fimmu.2020.00487 · External reference
10.1016/j.autrev.2012.10.001
10.1016/j.autrev.2012.10.001 · External reference
10.3389/fimmu.2023.1125116
10.3389/fimmu.2023.1125116 · External reference
PPARalpha: An emerging target of metabolic syndrome, neurodegenerative and cardiovascular diseases
10.3389/fendo.2022.1074911 · 2022 · External reference
Angiogenic signaling pathways and anti-angiogenic therapy for cancer
10.1038/s41392-023-01460-1 · 2023 · External reference
10.1186/s13059-014-0550-8
10.1186/s13059-014-0550-8 · External reference
IL-20 promotes cutaneous inflammation and peripheral itch sensation in atopic dermatitis
10.1096/fj.202101800r · 2022 · External reference
10.3389/fimmu.2025.1717370
10.3389/fimmu.2025.1717370 · External reference
10.3389/fimmu.2021.808012
10.3389/fimmu.2021.808012 · External reference
Interleukin-17 Family Cytokines in Metabolic Disorders and Cancer
10.3390/genes13091643 · 2022 · External reference
10.1111/cod.13959
10.1111/cod.13959 · External reference
10.1186/s12944-017-0608-1
10.1186/s12944-017-0608-1 · External reference
Novel translational model of resolving inflammation triggered by UV-killed E. coli
10.1002/cjp2.43 · 2016 · External reference
10.1093/cei/uxac079
10.1093/cei/uxac079 · External reference
FGF21 and its underlying adipose tissue-liver axis inform cardiometabolic burden and improvement in obesity after metabolic surgery
10.1016/j.ebiom.2024.105458 · 2024 · External reference
Cardiometabolic characteristics of people with metabolically healthy and unhealthy obesity
10.1016/j.cmet.2024.03.002 · 2024 · External reference
Epithelial-derived cytokines in the pathogenesis of severe asthma
10.3389/falgy.2025.1681147 · 2025 · External reference
10.1111/bph.12713
10.1111/bph.12713 · External reference
10.1016/j.cellsig.2018.11.004
10.1016/j.cellsig.2018.11.004 · External reference
10.1016/s0140-6736(21)00520-1
10.1016/s0140-6736(21)00520-1 · External reference
10.1056/nejmoa1707914
10.1056/nejmoa1707914 · External reference
10.1161/circulationaha.112.122556
10.1161/circulationaha.112.122556 · External reference
10.1016/s0140-6736(17)32814-3
10.1016/s0140-6736(17)32814-3 · External reference
10.1136/bmjopen-2020-039996
10.1136/bmjopen-2020-039996 · External reference
10.1016/j.jaci.2020.03.041
10.1016/j.jaci.2020.03.041 · External reference
Laser Doppler imager (LDI) scanner and intradermal injection for in vivo pharmacology in human skin microcirculation: responses to acetylcholine, endothelin-1 and their repeatability
10.1111/j.1365-2125.2004.02344.x · 2005 · External reference
10.1007/s11154-023-09796-3
10.1007/s11154-023-09796-3 · External reference
10.1096/fj.06-7227rev
10.1096/fj.06-7227rev · External reference
10.1242/jcs.02346
10.1242/jcs.02346 · External reference
10.3390/ijms20184658
10.3390/ijms20184658 · External reference
10.1038/s41574-024-01047-y
10.1038/s41574-024-01047-y · External reference
Lipoxins reduce obesity-induced adipose tissue inflammation in 3D-cultured human adipocytes and explant cultures
2022 · External reference
Inflammation biomarkers and inflammatory genes expression in metabolically healthy obese patients
10.1016/j.numecd.2022.12.008 · 2023 · External reference
10.1210/jc.2010-1170
10.1210/jc.2010-1170 · External reference
Metabolic syndrome and inflammatory skin conditions
10.1097/mop.0000000000000790 · 2019 · External reference
10.1016/j.cmet.2017.07.008
10.1016/j.cmet.2017.07.008 · External reference
Differences in the levels of inflammatory markers between metabolically healthy obese and other obesity phenotypes in adults: A systematic review and meta-analysis
10.1016/j.numecd.2023.09.002 · 2024 · External reference
10.3389/fimmu.2016.00160
10.3389/fimmu.2016.00160 · External reference
10.1101/gad.267708.115
10.1101/gad.267708.115 · External reference
10.3389/fimmu.2021.648182
10.3389/fimmu.2021.648182 · External reference
Association of plasminogen activator inhibitor-1 and fibroblastic growth factor 21 in 3 groups of type 2 diabetes: Without overweight/obesity, free of insulin resistance, and without hepatosteatosis
10.1097/md.0000000000034797 · 2023 · External reference
Interrelationship and Sequencing of Interleukins4, 13, 31, and 33 - An Integrated Systematic Review: Dermatological and Multidisciplinary Perspectives
10.2147/jir.s374060 · 2022 · External reference
10.1038/oby.2011.142
10.1038/oby.2011.142 · External reference
10.1038/s41423-025-01380-w
10.1038/s41423-025-01380-w · External reference
10.1073/pnas.2114739119
10.1073/pnas.2114739119 · External reference
Systemic immune dysregulation in severe tuberculosis patients revealed by a single-cell transcriptome atlas
10.1016/j.jinf.2023.03.020 · 2023 · External reference
Persistent neutrophil activation despite count normalization suggests immune dysregulation in exertional heat stroke
2025 · External reference
Skin wound closure delay in metabolic syndrome correlates with SCF deficiency in keratinocytes
10.1038/s41598-020-78244-y · 2020 · External reference
Neutralizing IL-22RA1 improves histologic and molecular alterations associated with atopic dermatitis pathogenesis
10.1016/j.jaci.2025.08.033 · 2026 · External reference
10.3389/fimmu.2012.00368
10.3389/fimmu.2012.00368 · External reference
Macrophage plasticity: signaling pathways, tissue repair, and regeneration
2024 · External reference
10.1089/omi.2011.0118
10.1089/omi.2011.0118 · External reference
An Empirically Derived Definition of Metabolically Healthy Obesity Based on Risk of Cardiovascular and Total Mortality
10.1001/jamanetworkopen.2021.8505 · 2021 · External reference
CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment
10.1038/ncomms11674 · 2016 · External reference
High expression of CCL3/CCL4/CCL5/CCR5 promotes exhausted CD8(+) T cells terminal differentiation and is associated with poor prognosis in pediatric B-ALL patients
10.1177/03946320251346823 · 2025 · External reference
ST2L promotes VEGFA-mediated angiogenesis in gastric cancer by activating TRAF6/PI3K/Akt/NF-kappaB pathway via IL-33
10.1038/s41598-024-76763-6 · 2024 · External reference
An Empirically Derived Definition of Metabolically Healthy Obesity Based on Risk of Cardiovascular and Total Mortality
10.1001/jamanetworkopen.2021.8505 · ExternalCitation · doi-reference
Novel translational model of resolving inflammation triggered by UV-killed E. coli
10.1002/cjp2.43 · ExternalCitation · doi-reference
10.1002/jcp.22385
10.1002/jcp.22385 · ExternalCitation · doi-reference
10.1007/s00125-016-4036-y
10.1007/s00125-016-4036-y · ExternalCitation · doi-reference
10.1007/s10238-024-01508-8
10.1007/s10238-024-01508-8 · ExternalCitation · doi-reference
10.1007/s11154-023-09796-3
10.1007/s11154-023-09796-3 · ExternalCitation · doi-reference
High levels of LIGHT/TNFSF14 in patients with Prader-Willi syndrome
10.1007/s40618-023-02050-2 · ExternalCitation · doi-reference
10.1016/j.ajpath.2015.01.020
10.1016/j.ajpath.2015.01.020 · ExternalCitation · doi-reference
10.1016/j.autrev.2012.10.001
10.1016/j.autrev.2012.10.001 · ExternalCitation · doi-reference
10.1016/j.biocel.2007.10.024
10.1016/j.biocel.2007.10.024 · ExternalCitation · doi-reference
10.1016/j.cellsig.2018.11.004
10.1016/j.cellsig.2018.11.004 · ExternalCitation · doi-reference
Insights on the role of the chemokine CCL8 in pathology
10.1016/j.cellsig.2025.111951 · ExternalCitation · doi-reference
10.1016/j.cmet.2017.07.008
10.1016/j.cmet.2017.07.008 · ExternalCitation · doi-reference
Cardiometabolic characteristics of people with metabolically healthy and unhealthy obesity
10.1016/j.cmet.2024.03.002 · ExternalCitation · doi-reference
10.1016/j.diabres.2014.04.006
10.1016/j.diabres.2014.04.006 · ExternalCitation · doi-reference
FGF21 and its underlying adipose tissue-liver axis inform cardiometabolic burden and improvement in obesity after metabolic surgery
10.1016/j.ebiom.2024.105458 · ExternalCitation · doi-reference
10.1016/j.jaci.2020.03.041
10.1016/j.jaci.2020.03.041 · ExternalCitation · doi-reference
Neutralizing IL-22RA1 improves histologic and molecular alterations associated with atopic dermatitis pathogenesis
10.1016/j.jaci.2025.08.033 · ExternalCitation · doi-reference
Systemic immune dysregulation in severe tuberculosis patients revealed by a single-cell transcriptome atlas
10.1016/j.jinf.2023.03.020 · ExternalCitation · doi-reference
10.1016/j.metabol.2018.11.009
10.1016/j.metabol.2018.11.009 · ExternalCitation · doi-reference
Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes
10.1016/j.molmet.2015.04.002 · ExternalCitation · doi-reference
10.1016/j.mvr.2011.01.002
10.1016/j.mvr.2011.01.002 · ExternalCitation · doi-reference
Inflammation biomarkers and inflammatory genes expression in metabolically healthy obese patients
10.1016/j.numecd.2022.12.008 · ExternalCitation · doi-reference
Differences in the levels of inflammatory markers between metabolically healthy obese and other obesity phenotypes in adults: A systematic review and meta-analysis
10.1016/j.numecd.2023.09.002 · ExternalCitation · doi-reference
10.1016/j.pharmthera.2020.107670
10.1016/j.pharmthera.2020.107670 · ExternalCitation · doi-reference
10.1016/s0140-6736(17)32814-3
10.1016/s0140-6736(17)32814-3 · ExternalCitation · doi-reference
10.1016/s0140-6736(21)00520-1
10.1016/s0140-6736(21)00520-1 · ExternalCitation · doi-reference
10.1038/ijo.2009.199
10.1038/ijo.2009.199 · ExternalCitation · doi-reference
CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment
10.1038/ncomms11674 · ExternalCitation · doi-reference
10.1038/nrm1619
10.1038/nrm1619 · ExternalCitation · doi-reference
10.1038/oby.2011.142
10.1038/oby.2011.142 · ExternalCitation · doi-reference
Angiogenic signaling pathways and anti-angiogenic therapy for cancer
10.1038/s41392-023-01460-1 · ExternalCitation · doi-reference
Tissue macrophages: origin, heterogenity, biological functions, diseases and therapeutic targets
10.1038/s41392-025-02124-y · ExternalCitation · doi-reference
10.1038/s41423-025-01380-w
10.1038/s41423-025-01380-w · ExternalCitation · doi-reference
TREM1 signaling amplifies neutrophil-mediated inflammation in inflammatory bowel disease
10.1038/s41467-026-75319-8 · ExternalCitation · doi-reference
10.1038/s41574-024-01047-y
10.1038/s41574-024-01047-y · ExternalCitation · doi-reference
10.1038/s41590-020-0646-0
10.1038/s41590-020-0646-0 · ExternalCitation · doi-reference
10.1038/s41591-019-0675-0
10.1038/s41591-019-0675-0 · ExternalCitation · doi-reference
Skin wound closure delay in metabolic syndrome correlates with SCF deficiency in keratinocytes
10.1038/s41598-020-78244-y · ExternalCitation · doi-reference
Effects of interleukin-1 antagonism and corticosteroids on fibroblast growth factor-21 in patients with metabolic syndrome
10.1038/s41598-021-87207-w · ExternalCitation · doi-reference
Joint effect of BMI and metabolic status on mortality among adults: a population-based longitudinal study in United States
10.1038/s41598-024-53229-3 · ExternalCitation · doi-reference
ST2L promotes VEGFA-mediated angiogenesis in gastric cancer by activating TRAF6/PI3K/Akt/NF-kappaB pathway via IL-33
10.1038/s41598-024-76763-6 · ExternalCitation · doi-reference
10.1042/ebc20200018
10.1042/ebc20200018 · ExternalCitation · doi-reference
10.1056/nejmoa1707914
10.1056/nejmoa1707914 · ExternalCitation · doi-reference
10.1073/pnas.2114739119
10.1073/pnas.2114739119 · ExternalCitation · doi-reference
10.1089/omi.2011.0118
10.1089/omi.2011.0118 · ExternalCitation · doi-reference
Metalloproteinases and Wound Healing
10.1089/wound.2014.0581 · ExternalCitation · doi-reference
10.1093/bioinformatics/btw313
10.1093/bioinformatics/btw313 · ExternalCitation · doi-reference
10.1093/cei/uxac079
10.1093/cei/uxac079 · ExternalCitation · doi-reference
10.1096/fj.06-7227rev
10.1096/fj.06-7227rev · ExternalCitation · doi-reference
IL-20 promotes cutaneous inflammation and peripheral itch sensation in atopic dermatitis
10.1096/fj.202101800r · ExternalCitation · doi-reference
Association of plasminogen activator inhibitor-1 and fibroblastic growth factor 21 in 3 groups of type 2 diabetes: Without overweight/obesity, free of insulin resistance, and without hepatosteatosis
10.1097/md.0000000000034797 · ExternalCitation · doi-reference
Metabolic syndrome and inflammatory skin conditions
10.1097/mop.0000000000000790 · ExternalCitation · doi-reference
10.1101/gad.267708.115
10.1101/gad.267708.115 · ExternalCitation · doi-reference
10.1111/acel.13583
10.1111/acel.13583 · ExternalCitation · doi-reference
10.1111/bph.12713
10.1111/bph.12713 · ExternalCitation · doi-reference
10.1111/cod.13959
10.1111/cod.13959 · ExternalCitation · doi-reference
An overview of obesity-related complications: The epidemiological evidence linking body weight and other markers of obesity to adverse health outcomes. Diabetes
10.1111/dom.16263 · ExternalCitation · doi-reference
10.1111/iwj.70035
10.1111/iwj.70035 · ExternalCitation · doi-reference
Laser Doppler imager (LDI) scanner and intradermal injection for in vivo pharmacology in human skin microcirculation: responses to acetylcholine, endothelin-1 and their repeatability
10.1111/j.1365-2125.2004.02344.x · ExternalCitation · doi-reference
10.1111/joim.12384
10.1111/joim.12384 · ExternalCitation · doi-reference
10.1136/bmjdrc-2025-005118
10.1136/bmjdrc-2025-005118 · ExternalCitation · doi-reference
10.1136/bmjopen-2020-039996
10.1136/bmjopen-2020-039996 · ExternalCitation · doi-reference
10.1146/annurev-nutr-071816-064800
10.1146/annurev-nutr-071816-064800 · ExternalCitation · doi-reference
10.1155/2012/476380
10.1155/2012/476380 · ExternalCitation · doi-reference
10.1159/000088261
10.1159/000088261 · ExternalCitation · doi-reference
10.1161/circulationaha.112.122556
10.1161/circulationaha.112.122556 · ExternalCitation · doi-reference
High expression of CCL3/CCL4/CCL5/CCR5 promotes exhausted CD8(+) T cells terminal differentiation and is associated with poor prognosis in pediatric B-ALL patients
10.1177/03946320251346823 · ExternalCitation · doi-reference
Tumor Necrosis Factor: A Master Regulator in Inflammation and Disease-Pathways, Implications, and Breakthrough Therapies
10.1177/10799907261418982 · ExternalCitation · doi-reference
10.1186/s12944-017-0608-1
10.1186/s12944-017-0608-1 · ExternalCitation · doi-reference
10.1186/s13059-014-0550-8
10.1186/s13059-014-0550-8 · ExternalCitation · doi-reference
10.1210/endrev/bnaa004
10.1210/endrev/bnaa004 · ExternalCitation · doi-reference
10.1210/jc.2010-1170
10.1210/jc.2010-1170 · ExternalCitation · doi-reference
10.1242/jcs.02346
10.1242/jcs.02346 · ExternalCitation · doi-reference
10.1258/cvd.2012.012008
10.1258/cvd.2012.012008 · ExternalCitation · doi-reference
Characterisation of leukocytes in a human skin blister model of acute inflammation and resolution
10.1371/journal.pone.0089375 · ExternalCitation · doi-reference
Metabolically healthy obese individuals present similar chronic inflammation level but less insulin-resistance than obese individuals with metabolic syndrome
10.1371/journal.pone.0190528 · ExternalCitation · doi-reference
Interrelationship and Sequencing of Interleukins4, 13, 31, and 33 - An Integrated Systematic Review: Dermatological and Multidisciplinary Perspectives
10.2147/jir.s374060 · ExternalCitation · doi-reference
Update on the epidermal differentiation complex
10.2741/4001 · ExternalCitation · doi-reference
10.3109/03008207.2013.822865
10.3109/03008207.2013.822865 · ExternalCitation · doi-reference
Epithelial-derived cytokines in the pathogenesis of severe asthma
10.3389/falgy.2025.1681147 · ExternalCitation · doi-reference
Mechanisms Involved in Childhood Obesity-Related Bone Fragility
10.3389/fendo.2019.00269 · ExternalCitation · doi-reference
PPARalpha: An emerging target of metabolic syndrome, neurodegenerative and cardiovascular diseases
10.3389/fendo.2022.1074911 · ExternalCitation · doi-reference
10.3389/fimmu.2012.00368
10.3389/fimmu.2012.00368 · ExternalCitation · doi-reference
10.3389/fimmu.2016.00160
10.3389/fimmu.2016.00160 · ExternalCitation · doi-reference
10.3389/fimmu.2017.00254
10.3389/fimmu.2017.00254 · ExternalCitation · doi-reference
10.3389/fimmu.2020.00487
10.3389/fimmu.2020.00487 · ExternalCitation · doi-reference
10.3389/fimmu.2021.648182
10.3389/fimmu.2021.648182 · ExternalCitation · doi-reference
10.3389/fimmu.2021.808012
10.3389/fimmu.2021.808012 · ExternalCitation · doi-reference
10.3389/fimmu.2022.861931
10.3389/fimmu.2022.861931 · ExternalCitation · doi-reference
10.3389/fimmu.2022.876515
10.3389/fimmu.2022.876515 · ExternalCitation · doi-reference
10.3389/fimmu.2023.1125116
10.3389/fimmu.2023.1125116 · ExternalCitation · doi-reference
10.3389/fimmu.2025.1717370
10.3389/fimmu.2025.1717370 · ExternalCitation · doi-reference
Interleukin-17 Family Cytokines in Metabolic Disorders and Cancer
10.3390/genes13091643 · ExternalCitation · doi-reference
10.3390/ijms20184658
10.3390/ijms20184658 · ExternalCitation · doi-reference
State of Cutaneous Microcirculation in Patients with Obesity
10.36740/wlek202109103 · ExternalCitation · doi-reference
