Research graph
References from Activation of a STAT3/LATS1 Signaling Axis by Folate Receptor α Enables Breast Cancer Cells to Resist Physiological Ferroptotic Stress. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1016/j.cell.2012.03.042
10.1016/j.cell.2012.03.042 · External reference
Ferroptosis and metastasis: molecular checkpoints, microenvironmental dynamics, and therapeutic opportunities
10.1186/s12943-025-02544-y · 2026 · External reference
Ferroptosis in cancer: from molecular mechanisms to therapeutic strategies
10.1038/s41392-024-01769-5 · 2024 · External reference
10.1083/jcb.201701136
10.1083/jcb.201701136 · External reference
Cancer cell stiffening via CoQ(10) and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer
10.1038/s41467-024-52523-y · 2024 · External reference
10.1016/j.celrep.2025.116543
10.1016/j.celrep.2025.116543 · External reference
Targeting FSP1 triggers ferroptosis in lung cancer
10.1038/s41586-025-09710-8 · 2026 · External reference
GATA3 promotes ferroptosis resistance by repressing integrin β1 signaling
10.1073/pnas.2427304122 · 2025 · External reference
Folate receptor-α (FOLR1) expression and function in triple negative tumors
10.1371/journal.pone.0122209 · 2015 · External reference
Folate Receptor Alpha Expression Is Associated With Increased Risk of Recurrence in Triple-negative Breast Cancer
10.1016/j.clbc.2017.03.007 · 2017 · External reference
10.1158/1078-0432.ccr-18-0652
10.1158/1078-0432.ccr-18-0652 · External reference
10.1186/2193-1801-1-22
10.1186/2193-1801-1-22 · External reference
The Efficacy and Safety of Folate Receptor α-Targeted Antibody-Drug Conjugate Therapy in Patients With High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers: A Systematic Review and Meta-Analysis
10.1002/cam4.70392 · 2024 · External reference
Therapeutic induction of ferroptosis in tumors using PD-L1 targeting antibody nanogel conjugates
10.1016/j.chembiol.2024.10.014 · 2024 · External reference
10.1158/0008-5472.can-24-4207
10.1158/0008-5472.can-24-4207 · External reference
Reprogramming of iron metabolism confers ferroptosis resistance in ECM-detached cells
10.1016/j.isci.2023.106827 · 2023 · External reference
Detachment-Induced FAK-STAT3-NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation
2026 · External reference
10.1016/j.cellsig.2015.03.020
10.1016/j.cellsig.2015.03.020 · External reference
10.1016/j.tem.2021.12.003
10.1016/j.tem.2021.12.003 · External reference
Unresolved reference
External reference
The role of STAT3 in regulating ferroptosis in cancer: molecular mechanisms and targeted therapeutic perspectives
10.1038/s41417-026-01037-4 · 2026 · External reference
10.1083/jcb.124.4.619
10.1083/jcb.124.4.619 · External reference
Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export
10.1016/j.devcel.2019.10.007 · 2019 · External reference
10.1016/j.cmet.2019.07.014
10.1016/j.cmet.2019.07.014 · External reference
Cancer stem cell regulated phenotypic plasticity protects metastasized cancer cells from ferroptosis
10.1038/s41467-022-29018-9 · 2022 · External reference
10.1038/s41586-020-2623-z
10.1038/s41586-020-2623-z · External reference
10.1038/s41467-021-25354-4
10.1038/s41467-021-25354-4 · External reference
10.1038/s41586-019-1426-6
10.1038/s41586-019-1426-6 · External reference
Mapping the immune environment in clear cell renal carcinoma by single-cell genomics
10.1038/s42003-020-01625-6 · 2021 · External reference
10.1038/nbt.4096
10.1038/nbt.4096 · External reference
10.7554/elife.02523
10.7554/elife.02523 · External reference
The Efficacy and Safety of Folate Receptor α-Targeted Antibody-Drug Conjugate Therapy in Patients With High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers: A Systematic Review and Meta-Analysis
10.1002/cam4.70392 · ExternalCitation · doi-reference
10.1016/j.cell.2012.03.042
10.1016/j.cell.2012.03.042 · ExternalCitation · doi-reference
10.1016/j.cellsig.2015.03.020
10.1016/j.cellsig.2015.03.020 · ExternalCitation · doi-reference
10.1016/j.celrep.2025.116543
10.1016/j.celrep.2025.116543 · ExternalCitation · doi-reference
Therapeutic induction of ferroptosis in tumors using PD-L1 targeting antibody nanogel conjugates
10.1016/j.chembiol.2024.10.014 · ExternalCitation · doi-reference
Folate Receptor Alpha Expression Is Associated With Increased Risk of Recurrence in Triple-negative Breast Cancer
10.1016/j.clbc.2017.03.007 · ExternalCitation · doi-reference
10.1016/j.cmet.2019.07.014
10.1016/j.cmet.2019.07.014 · ExternalCitation · doi-reference
Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export
10.1016/j.devcel.2019.10.007 · ExternalCitation · doi-reference
Reprogramming of iron metabolism confers ferroptosis resistance in ECM-detached cells
10.1016/j.isci.2023.106827 · ExternalCitation · doi-reference
10.1016/j.tem.2021.12.003
10.1016/j.tem.2021.12.003 · ExternalCitation · doi-reference
10.1038/nbt.4096
10.1038/nbt.4096 · ExternalCitation · doi-reference
Ferroptosis in cancer: from molecular mechanisms to therapeutic strategies
10.1038/s41392-024-01769-5 · ExternalCitation · doi-reference
The role of STAT3 in regulating ferroptosis in cancer: molecular mechanisms and targeted therapeutic perspectives
10.1038/s41417-026-01037-4 · ExternalCitation · doi-reference
10.1038/s41467-021-25354-4
10.1038/s41467-021-25354-4 · ExternalCitation · doi-reference
Cancer stem cell regulated phenotypic plasticity protects metastasized cancer cells from ferroptosis
10.1038/s41467-022-29018-9 · ExternalCitation · doi-reference
Cancer cell stiffening via CoQ(10) and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer
10.1038/s41467-024-52523-y · ExternalCitation · doi-reference
10.1038/s41586-019-1426-6
10.1038/s41586-019-1426-6 · ExternalCitation · doi-reference
10.1038/s41586-020-2623-z
10.1038/s41586-020-2623-z · ExternalCitation · doi-reference
Targeting FSP1 triggers ferroptosis in lung cancer
10.1038/s41586-025-09710-8 · ExternalCitation · doi-reference
Mapping the immune environment in clear cell renal carcinoma by single-cell genomics
10.1038/s42003-020-01625-6 · ExternalCitation · doi-reference
GATA3 promotes ferroptosis resistance by repressing integrin β1 signaling
10.1073/pnas.2427304122 · ExternalCitation · doi-reference
10.1083/jcb.124.4.619
10.1083/jcb.124.4.619 · ExternalCitation · doi-reference
10.1083/jcb.201701136
10.1083/jcb.201701136 · ExternalCitation · doi-reference
10.1158/0008-5472.can-24-4207
10.1158/0008-5472.can-24-4207 · ExternalCitation · doi-reference
10.1158/1078-0432.ccr-18-0652
10.1158/1078-0432.ccr-18-0652 · ExternalCitation · doi-reference
10.1186/2193-1801-1-22
10.1186/2193-1801-1-22 · ExternalCitation · doi-reference
Ferroptosis and metastasis: molecular checkpoints, microenvironmental dynamics, and therapeutic opportunities
10.1186/s12943-025-02544-y · ExternalCitation · doi-reference
Folate receptor-α (FOLR1) expression and function in triple negative tumors
10.1371/journal.pone.0122209 · ExternalCitation · doi-reference
10.7554/elife.02523
10.7554/elife.02523 · ExternalCitation · doi-reference
