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References from ERK5 inhibition triggers CDK6 proteasomal degradation and enhances palbociclib efficacy in cancer cells. Local targets link to admitted publications; unresolved targets remain external evidence.
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10.1002/cncr.32802 · External reference
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The MEK5/ERK5 pathway promotes the activation of the Hedgehog/GLI signaling in melanoma cells
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MEK5/ERK5 signaling inhibition increases colon cancer cell sensitivity to 5-fluorouracil through a p53-dependent mechanism
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Safety assessment of cyclin-dependent kinase 4/6 inhibitors and comparison of time to adverse events
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Impact of CDK4/6 inhibitors on health-related quality of life outcomes in patients with metastatic breast cancer: A systematic review and meta-analysis
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Palbociclib in advanced acral melanoma with genetic aberrations in the cyclin-dependent kinase 4 pathway
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Different BCR/Abl protein suppression patterns as a converging trait of chronic myeloid leukemia cell adaptation to energy restriction
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MEK5/ERK5 signaling inhibition increases colon cancer cell sensitivity to 5-fluorouracil through a p53-dependent mechanism
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ERK5/BMK1 Is Indispensable for Optimal Colony-Stimulating Factor 1 (CSF-1)-Induced Proliferation in Macrophages in a Src-Dependent Fashion
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