Research graph
References from <i>NAT10</i> supports CAG repeat-associated mRNA stabilization and is associated with hepatic metabolic reprogramming during spaceflight. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1126/science.aau8650
10.1126/science.aau8650 · External reference
10.1016/j.cell.2020.10.050
10.1016/j.cell.2020.10.050 · External reference
Spaceflight activates autophagy programs and the proteasome in mouse liver
10.3390/ijms18102062 · 2017 · External reference
Hepatology in space: Effects of spaceflight and simulated microgravity on the liver
10.1111/liv.15444 · 2022 · External reference
10.1021/acschembio.6b00960
10.1021/acschembio.6b00960 · External reference
10.1038/nrm3785
10.1038/nrm3785 · External reference
10.1261/rna.054502.115
10.1261/rna.054502.115 · External reference
Nucleic acid modifications in regulation of gene expression
10.1016/j.chembiol.2015.11.007 · 2016 · External reference
10.1126/science.aad8711
10.1126/science.aad8711 · External reference
10.1038/nrm.2016.132
10.1038/nrm.2016.132 · External reference
10.1016/j.cell.2018.10.030
10.1016/j.cell.2018.10.030 · External reference
10.1016/j.cell.2018.11.037
10.1016/j.cell.2018.11.037 · External reference
10.1126/science.1252651
10.1126/science.1252651 · External reference
10.3390/cells8091035
10.3390/cells8091035 · External reference
10.1093/nar/gkv075
10.1093/nar/gkv075 · External reference
10.1016/j.molcel.2024.03.017
10.1016/j.molcel.2024.03.017 · External reference
10.1016/j.molcel.2024.03.018
10.1016/j.molcel.2024.03.018 · External reference
10.1016/j.pharmthera.2023.108576
10.1016/j.pharmthera.2023.108576 · External reference
10.1016/j.bcp.2023.115628
10.1016/j.bcp.2023.115628 · External reference
Mechanisms of NAT10 as ac4C writer in diseases
10.1016/j.omtn.2023.03.023 · 2023 · External reference
10.1128/mcb.15.4.2219
10.1128/mcb.15.4.2219 · External reference
10.1073/pnas.1711283114
10.1073/pnas.1711283114 · External reference
10.1073/pnas.0909740107
10.1073/pnas.0909740107 · External reference
10.1093/nar/gku658
10.1093/nar/gku658 · External reference
10.1093/nar/gkq935
10.1093/nar/gkq935 · External reference
10.1371/journal.pbio.3001940
10.1371/journal.pbio.3001940 · External reference
Repeat-associated non-ATG translation: molecular mechanisms and contribution to neurological disease
10.1146/annurev-neuro-070918-050405 · 2019 · External reference
Huntington’s disease mechanisms and therapeutic strategies
2016 · External reference
10.1021/bi401129r
10.1021/bi401129r · External reference
10.1038/s41556-018-0045-z
10.1038/s41556-018-0045-z · External reference
NAT10: An RNA cytidine transferase regulates fatty acid metabolism in cancer cells
10.1002/ctm2.1045 · 2022 · External reference
NAT10 promotes gallbladder cancer progression by remodeling cholesterol metabolism via PCSK9 mRNA acetylation
10.1038/s41420-026-03104-z · 2026 · External reference
NAT10 promotes liver lipogenesis in mouse through N4-acetylcytidine modification of Srebf1 and Scap mRNA
2024 · External reference
Improvement of MASLD and MASH by suppression of hepatic N-acetyltransferase 10
2024 · External reference
NAT10 is upregulated in hepatocellular carcinoma and enhances mutant p53 activity
2017 · External reference
10.1038/s41598-025-00707-x
10.1038/s41598-025-00707-x · External reference
10.15252/embj.2020104708
10.15252/embj.2020104708 · External reference
10.1006/meth.2001.1262
10.1006/meth.2001.1262 · External reference
NAT10 promotes tubular epithelial cell senescence in cisplatin-induced acute kidney injury by regulating DDX17
10.7150/ijbs.127909 · 2026 · External reference
NAT10: An RNA cytidine transferase regulates fatty acid metabolism in cancer cells
10.1002/ctm2.1045 · ExternalCitation · doi-reference
10.1006/meth.2001.1262
10.1006/meth.2001.1262 · ExternalCitation · doi-reference
10.1016/j.bcp.2023.115628
10.1016/j.bcp.2023.115628 · ExternalCitation · doi-reference
10.1016/j.cell.2018.10.030
10.1016/j.cell.2018.10.030 · ExternalCitation · doi-reference
10.1016/j.cell.2018.11.037
10.1016/j.cell.2018.11.037 · ExternalCitation · doi-reference
10.1016/j.cell.2020.10.050
10.1016/j.cell.2020.10.050 · ExternalCitation · doi-reference
Nucleic acid modifications in regulation of gene expression
10.1016/j.chembiol.2015.11.007 · ExternalCitation · doi-reference
10.1016/j.molcel.2024.03.017
10.1016/j.molcel.2024.03.017 · ExternalCitation · doi-reference
10.1016/j.molcel.2024.03.018
10.1016/j.molcel.2024.03.018 · ExternalCitation · doi-reference
Mechanisms of NAT10 as ac4C writer in diseases
10.1016/j.omtn.2023.03.023 · ExternalCitation · doi-reference
10.1016/j.pharmthera.2023.108576
10.1016/j.pharmthera.2023.108576 · ExternalCitation · doi-reference
10.1021/acschembio.6b00960
10.1021/acschembio.6b00960 · ExternalCitation · doi-reference
10.1021/bi401129r
10.1021/bi401129r · ExternalCitation · doi-reference
10.1038/nrm.2016.132
10.1038/nrm.2016.132 · ExternalCitation · doi-reference
10.1038/nrm3785
10.1038/nrm3785 · ExternalCitation · doi-reference
NAT10 promotes gallbladder cancer progression by remodeling cholesterol metabolism via PCSK9 mRNA acetylation
10.1038/s41420-026-03104-z · ExternalCitation · doi-reference
10.1038/s41556-018-0045-z
10.1038/s41556-018-0045-z · ExternalCitation · doi-reference
10.1038/s41598-025-00707-x
10.1038/s41598-025-00707-x · ExternalCitation · doi-reference
10.1073/pnas.0909740107
10.1073/pnas.0909740107 · ExternalCitation · doi-reference
10.1073/pnas.1711283114
10.1073/pnas.1711283114 · ExternalCitation · doi-reference
10.1093/nar/gkq935
10.1093/nar/gkq935 · ExternalCitation · doi-reference
10.1093/nar/gku658
10.1093/nar/gku658 · ExternalCitation · doi-reference
10.1093/nar/gkv075
10.1093/nar/gkv075 · ExternalCitation · doi-reference
Hepatology in space: Effects of spaceflight and simulated microgravity on the liver
10.1111/liv.15444 · ExternalCitation · doi-reference
10.1126/science.1252651
10.1126/science.1252651 · ExternalCitation · doi-reference
10.1126/science.aad8711
10.1126/science.aad8711 · ExternalCitation · doi-reference
10.1126/science.aau8650
10.1126/science.aau8650 · ExternalCitation · doi-reference
10.1128/mcb.15.4.2219
10.1128/mcb.15.4.2219 · ExternalCitation · doi-reference
Repeat-associated non-ATG translation: molecular mechanisms and contribution to neurological disease
10.1146/annurev-neuro-070918-050405 · ExternalCitation · doi-reference
10.1261/rna.054502.115
10.1261/rna.054502.115 · ExternalCitation · doi-reference
10.1371/journal.pbio.3001940
10.1371/journal.pbio.3001940 · ExternalCitation · doi-reference
10.15252/embj.2020104708
10.15252/embj.2020104708 · ExternalCitation · doi-reference
10.3390/cells8091035
10.3390/cells8091035 · ExternalCitation · doi-reference
Spaceflight activates autophagy programs and the proteasome in mouse liver
10.3390/ijms18102062 · ExternalCitation · doi-reference
NAT10 promotes tubular epithelial cell senescence in cisplatin-induced acute kidney injury by regulating DDX17
10.7150/ijbs.127909 · ExternalCitation · doi-reference
