Research graph
References from Methadone Triggers Fetal Membrane Sterile Inflammation Through Innate Immune and Opioid Receptor Signaling. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1371/journal.pone.0261751
10.1371/journal.pone.0261751 · External reference
Risk factors for preterm birth among gravid individuals receiving buprenorphine for opioid use disorder
10.1016/j.ajogmf.2022.100582 · 2022 · External reference
10.1111/add.15054
10.1111/add.15054 · External reference
Unresolved reference
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10.1542/peds.2021-050279
10.1542/peds.2021-050279 · External reference
10.7554/elife.66230
10.7554/elife.66230 · External reference
10.1097/aog.0000000000002235
10.1097/aog.0000000000002235 · External reference
Disparities in receipt of medications for opioid use disorder among pregnant women
10.1080/08897077.2021.1949664 · 2022 · External reference
Buprenorphine Treatment in Pregnancy and Maternal-Infant Outcomes
10.1001/jamahealthforum.2025.1814 · 2025 · External reference
10.1016/j.siny.2006.05.001
10.1016/j.siny.2006.05.001 · External reference
10.1093/biolre/ioy261
10.1093/biolre/ioy261 · External reference
10.4049/jimmunol.1100578
10.4049/jimmunol.1100578 · External reference
10.1016/s0002-9440(10)63567-5
10.1016/s0002-9440(10)63567-5 · External reference
10.1095/biolreprod.103.019620
10.1095/biolreprod.103.019620 · External reference
10.1177/1933719107310992
10.1177/1933719107310992 · External reference
10.1093/biolre/ioy264
10.1093/biolre/ioy264 · External reference
10.1016/j.jri.2022.103786
10.1016/j.jri.2022.103786 · External reference
Buprenorphine induces human fetal membrane sterile inflammation
10.1016/j.jri.2025.104445 · 2025 · External reference
Human fetal membrane IL-1beta production in response to bacterial components is mediated by uric-acid induced NLRP3 inflammasome activation
2021 · External reference
TLR8-activating miR-146a-3p is an intermediate signal contributing to fetal membrane inflammation in response to bacterial LPS
10.1111/imm.13794 · 2024 · External reference
A role for TLR7 activation by miR-146a-3p in antiphospholipid antibody-induced trophoblast IL-8 and inflammasome-mediated IL-1beta production
10.1016/j.jri.2025.104652 · 2025 · External reference
10.1016/j.jri.2008.04.002
10.1016/j.jri.2008.04.002 · External reference
10.1016/j.placenta.2009.11.012
10.1016/j.placenta.2009.11.012 · External reference
Block of Granulocyte-Macrophage Colony-Stimulating Factor Prevents Inflammation-Induced Preterm Birth in a Mouse Model for Parturition
10.1177/1933719118804420 · 2019 · External reference
Macrophage inflammatory protein-1alpha in amniotic and cervical fluids in spontaneous preterm labor with intact membranes with respect to intra-amniotic inflammation
10.1080/14767058.2021.1922381 · 2022 · External reference
10.3390/cancers13215274
10.3390/cancers13215274 · External reference
10.1177/106002808101501205
10.1177/106002808101501205 · External reference
10.1093/molehr/gaw027
10.1093/molehr/gaw027 · External reference
Intermediate Signaling Mechanisms Regulating Human Fetal Membrane Responses to Gram-Positive Bacterial Peptidoglycan
10.1111/aji.70090 · 2025 · External reference
10.1101/2025.07.29.667498
10.1101/2025.07.29.667498 · External reference
10.4161/rna.23144
10.4161/rna.23144 · External reference
10.3389/fimmu.2014.00461
10.3389/fimmu.2014.00461 · External reference
10.1093/biolre/ioac003
10.1093/biolre/ioac003 · External reference
10.1095/biolreprod.104.028621
10.1095/biolreprod.104.028621 · External reference
10.1186/1477-7827-5-46
10.1186/1477-7827-5-46 · External reference
10.1095/biolreprod.113.115428
10.1095/biolreprod.113.115428 · External reference
10.1093/biolre/iox147
10.1093/biolre/iox147 · External reference
10.1093/biolre/ioab188
10.1093/biolre/ioab188 · External reference
10.1177/1933719116687656
10.1177/1933719116687656 · External reference
Opioid use disorder among pregnant women in the 2000-2014 North Carolina state inpatient database
10.1080/10550887.2020.1751023 · 2020 · External reference
10.1097/aln.0000000000000472
10.1097/aln.0000000000000472 · External reference
10.1186/1477-7827-7-61
10.1186/1477-7827-7-61 · External reference
Fetal Membrane Inflammation Induces Preterm Birth Via Toll-Like Receptor 2 in Mice With Chronic Gingivitis
10.1177/1933719118792097 · 2019 · External reference
10.1111/j.1600-0897.2005.00342.x
10.1111/j.1600-0897.2005.00342.x · External reference
Mu-opioid receptor and receptor tyrosine kinase crosstalk: Implications in mechanisms of opioid tolerance, reduced analgesia to neuropathic pain, dependence, and reward
10.3389/fnsys.2022.1059089 · 2022 · External reference
Buprenorphine-naloxone, buprenorphine, and methadone throughout pregnancy in maternal opioid use disorder
10.1111/aogs.14497 · 2023 · External reference
10.1080/14767058.2022.2130238
10.1080/14767058.2022.2130238 · External reference
Buprenorphine-naloxone versus buprenorphine for opioid use disorder during pregnancy: A systematic review and meta-analysis
10.1016/j.drugalcdep.2025.112632 · 2025 · External reference
