Research graph
References from Ryanodine receptor cluster remodeling links COL4A2 mutation to cerebral artery dysfunction. Local targets link to admitted publications; unresolved targets remain external evidence.
The pathogenesis of cerebral small vessel disease and vascular cognitive impairment
10.1152/physrev.00028.2024 · 2025 · External reference
10.1016/s1474-4422(10)70104-6
10.1016/s1474-4422(10)70104-6 · External reference
10.1161/strokeaha.113.002878
10.1161/strokeaha.113.002878 · External reference
10.1038/jcbfm.2015.62
10.1038/jcbfm.2015.62 · External reference
10.1126/science.1109418
10.1126/science.1109418 · External reference
10.1056/nejmoa053727
10.1056/nejmoa053727 · External reference
10.1161/strokeaha.110.581918
10.1161/strokeaha.110.581918 · External reference
Epilepsy and related challenges in children with COL4A1 and COL4A2 mutations: A Gould syndrome patient registry
10.1016/j.yebeh.2021.108365 · 2021 · External reference
10.1038/s41581-025-00982-x
10.1038/s41581-025-00982-x · External reference
The Expanding Phenotypic Spectrum of COL4A1- and COL4A2-Related Disorders: A Systematic Review
10.1016/j.pediatrneurol.2026.06.025 · 2026 · External reference
Multiorgan manifestations of COL4A1 and COL4A2 variants and proposal for a clinical management protocol
10.1002/ajmg.c.32099 · 2024 · External reference
10.1016/j.matbio.2016.10.003
10.1016/j.matbio.2016.10.003 · External reference
COL4A1 and COL4A2-related disorders: Clinical features, diagnostic guidelines, and management
10.1016/j.gim.2025.101514 · 2025 · External reference
10.1161/jaha.121.025629
10.1161/jaha.121.025629 · External reference
10.1212/wnl.0000000000001309
10.1212/wnl.0000000000001309 · External reference
10.1016/s1474-4422(21)00031-4
10.1016/s1474-4422(21)00031-4 · External reference
Faulty TRPM4 channels underlie age-dependent cerebral vascular dysfunction in Gould syndrome
10.1073/pnas.2217327120 · 2023 · External reference
10.1126/scisignal.adi3966
10.1126/scisignal.adi3966 · External reference
10.1073/pnas.2306479120
10.1073/pnas.2306479120 · External reference
10.1152/physrev.00053.2021
10.1152/physrev.00053.2021 · External reference
10.1161/01.res.0000147311.54833.03
10.1161/01.res.0000147311.54833.03 · External reference
10.1126/scisignal.2004732
10.1126/scisignal.2004732 · External reference
10.1161/strokeaha.107.483404
10.1161/strokeaha.107.483404 · External reference
10.1016/j.ajhg.2011.11.022
10.1016/j.ajhg.2011.11.022 · External reference
10.1161/circulationaha.114.013395
10.1161/circulationaha.114.013395 · External reference
10.1073/pnas.1420765112
10.1073/pnas.1420765112 · External reference
10.1152/ajpheart.01021.2020
10.1152/ajpheart.01021.2020 · External reference
Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions
10.1016/j.jmb.2020.09.024 · 2021 · External reference
10.1152/ajpcell.00550.2009
10.1152/ajpcell.00550.2009 · External reference
10.1126/science.270.5236.633
10.1126/science.270.5236.633 · External reference
10.1111/j.1469-7793.1998.211br.x
10.1111/j.1469-7793.1998.211br.x · External reference
10.1085/jgp.113.2.229
10.1085/jgp.113.2.229 · External reference
10.1113/jphysiol.2002.025197
10.1113/jphysiol.2002.025197 · External reference
10.1016/s0006-3495(01)75741-4
10.1016/s0006-3495(01)75741-4 · External reference
10.1073/pnas.0908971106
10.1073/pnas.0908971106 · External reference
10.1073/pnas.1804593115
10.1073/pnas.1804593115 · External reference
10.1016/j.bpj.2018.12.017
10.1016/j.bpj.2018.12.017 · External reference
10.1085/jgp.113.2.177
10.1085/jgp.113.2.177 · External reference
10.1371/journal.pcbi.1004417
10.1371/journal.pcbi.1004417 · External reference
10.7554/elife.70278
10.7554/elife.70278 · External reference
10.1364/ol.19.000780
10.1364/ol.19.000780 · External reference
10.1371/journal.pcbi.1010126
10.1371/journal.pcbi.1010126 · External reference
Frequency modulation of Ca2+ sparks is involved in regulation of arterial diameter by cyclic nucleotides
10.1152/ajpcell.1998.274.5.c1346 · 1998 · External reference
10.1152/ajpcell.2001.281.3.c1029
10.1152/ajpcell.2001.281.3.c1029 · External reference
10.1016/j.yjmcc.2012.03.015
10.1016/j.yjmcc.2012.03.015 · External reference
10.1073/pnas.0510113103
10.1073/pnas.0510113103 · External reference
10.1016/s0021-9258(18)81864-6
10.1016/s0021-9258(18)81864-6 · External reference
10.1038/jcbfm.2014.139
10.1038/jcbfm.2014.139 · External reference
10.1146/annurev-physiol-061121-040127
10.1146/annurev-physiol-061121-040127 · External reference
10.1161/circulationaha.119.040963
10.1161/circulationaha.119.040963 · External reference
10.1152/physrev.00022.2021
10.1152/physrev.00022.2021 · External reference
10.1161/jaha.118.008724
10.1161/jaha.118.008724 · External reference
10.7554/elife.77725
10.7554/elife.77725 · External reference
10.1016/j.yjmcc.2017.01.015
10.1016/j.yjmcc.2017.01.015 · External reference
10.1161/circresaha.115.303897
10.1161/circresaha.115.303897 · External reference
10.1074/jbc.rev120.007423
10.1074/jbc.rev120.007423 · External reference
10.1038/s41467-019-14040-1
10.1038/s41467-019-14040-1 · External reference
10.1126/scisignal.2005347
10.1126/scisignal.2005347 · External reference
10.1172/jci165368
10.1172/jci165368 · External reference
10.1534/genetics.106.064733
10.1534/genetics.106.064733 · External reference
10.1093/hmg/ddt560
10.1093/hmg/ddt560 · External reference
