Research graph
References from Angiopoietin-like protein 7 (ANGPTL7)-mediated effects on resident immune cells contribute to neurodegeneration in glaucomatous optic nerve head. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1001/jama.2014.3192
10.1001/jama.2014.3192 · External reference
10.1016/j.preteyeres.2021.100998
10.1016/j.preteyeres.2021.100998 · External reference
10.1038/s41598-024-52800-2
10.1038/s41598-024-52800-2 · External reference
Compliance and adherence in glaucoma management
2011 · External reference
10.3390/jpm12040514
10.3390/jpm12040514 · External reference
10.1371/journal.pgen.1008682
10.1371/journal.pgen.1008682 · External reference
10.1093/hmg/ddad083
10.1093/hmg/ddad083 · External reference
10.1167/iovs.07-1347
10.1167/iovs.07-1347 · External reference
Gene expression profile of human trabecular meshwork cells in response to long-term dexamethasone exposure
2006 · External reference
10.1167/iovs.02-0444
10.1167/iovs.02-0444 · External reference
ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma
10.1038/s42003-022-03932-6 · 2022 · External reference
10.1167/iovs.65.4.22
10.1167/iovs.65.4.22 · External reference
Alterations in proteome of human sclera associated with primary open-angle glaucoma involve proteins participating in regulation of the extracellular matrix
2020 · External reference
Loss of Angiopoietin-like 7 diminishes the regeneration capacity of hematopoietic stem and progenitor cells
10.1186/s13045-014-0102-4 · 2015 · External reference
10.1038/nature11095
10.1038/nature11095 · External reference
10.1016/j.exer.2010.09.006
10.1016/j.exer.2010.09.006 · External reference
Neurovascular dysfunction in glaucoma
10.1016/j.preteyeres.2023.101217 · 2023 · External reference
10.1016/j.exer.2017.02.014
10.1016/j.exer.2017.02.014 · External reference
10.1371/journal.pone.0196529
10.1371/journal.pone.0196529 · External reference
Multiparametric grading of glaucoma severity by histopathology can enable post-mortem substratification of disease state
10.1186/s40478-024-01880-2 · 2025 · External reference
10.1038/s41586-020-2734-6
10.1038/s41586-020-2734-6 · External reference
10.1038/nbt.1644
10.1038/nbt.1644 · External reference
Complement Factor B Inhibition or Deletion Is Not Sufficient to Prevent Neurodegeneration in a Murine Model of Glaucoma
10.1089/jop.2024.0046 · 2024 · External reference
10.1186/gb-2006-7-10-r100
10.1186/gb-2006-7-10-r100 · External reference
10.1073/pnas.0914019107
10.1073/pnas.0914019107 · External reference
10.1073/pnas.2001896117
10.1073/pnas.2001896117 · External reference
10.1073/pnas.2200914119
10.1073/pnas.2200914119 · External reference
Central Corneal Thickness and its Associations With Ocular and Systemic Factors in an Urban West African Population
10.1016/j.ajo.2016.07.004 · 2016 · External reference
Optic disc planimetry, corneal hysteresis, central corneal thickness, and intraocular pressure as risk factors for glaucoma
10.1016/j.ajo.2013.10.017 · 2014 · External reference
10.1182/blood-2014-01-549162
10.1182/blood-2014-01-549162 · External reference
10.18632/oncotarget.4217
10.18632/oncotarget.4217 · External reference
ANGPTL8 accelerates liver fibrosis mediated by HFD-induced inflammatory activity via LILRB2/ERK signaling pathways
10.1016/j.jare.2022.08.006 · 2023 · External reference
Differences in the state of differentiation of THP-1 cells induced by phorbol ester and 1,25-dihydroxyvitamin D3
10.1002/jlb.59.4.555 · 1996 · External reference
10.1371/journal.pone.0008668
10.1371/journal.pone.0008668 · External reference
10.2119/molmed.2014.00185
10.2119/molmed.2014.00185 · External reference
10.1074/jbc.m307583200
10.1074/jbc.m307583200 · External reference
10.1194/jlr.m400138-jlr200
10.1194/jlr.m400138-jlr200 · External reference
10.1016/j.bbamcr.2009.01.018
10.1016/j.bbamcr.2009.01.018 · External reference
10.1074/jbc.m500292200
10.1074/jbc.m500292200 · External reference
10.1371/journal.pone.0131176
10.1371/journal.pone.0131176 · External reference
10.1242/jcs.098020
10.1242/jcs.098020 · External reference
10.1006/geno.1999.6041
10.1006/geno.1999.6041 · External reference
10.3390/ijms19020431
10.3390/ijms19020431 · External reference
10.1167/iovs.05-0830
10.1167/iovs.05-0830 · External reference
Safety and Target Engagement of Complement C1q Inhibitor ANX007 in Neurodegenerative Eye Disease: Results from Phase I Studies in Glaucoma
10.1016/j.xops.2023.100290 · 2023 · External reference