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References from Single-cell spatial transcriptomics of inherited retinal degeneration reveals broad and focal organization of disease responses. Local targets link to admitted publications; unresolved targets remain external evidence.
Inherited retinal degenerations: clinical phenotypes and emerging therapies
10.1016/s0140-6736(26)00766-x · 2026 · External reference
10.1186/s12915-022-01280-9
10.1186/s12915-022-01280-9 · External reference
Single-cell transcriptomic profiling in inherited retinal degeneration reveals distinct metabolic pathways in rod and cone photoreceptors
10.3390/ijms232012170 · 2022 · External reference
A profile of transcriptomic changes in the rd10 mouse model of retinitis pigmentosa
2014 · External reference
Early manifestations and differential gene expression associated with photoreceptor degeneration in Prom1-deficient retina
10.1242/dmm.048962 · 2021 · External reference
10.1016/j.gendis.2026.102241
10.1016/j.gendis.2026.102241 · External reference
Single-cell transcriptomics in inherited retinal dystrophies: current findings and emerging perspectives
10.3390/genes16091088 · 2025 · External reference
10.1038/s12276-021-00693-w
10.1038/s12276-021-00693-w · External reference
Gene expression changes within Müller glial cells in retinitis pigmentosa
2012 · External reference
Illuminating photoreceptors: TGFβ signaling modulates the severeness of retinal degeneration
10.1038/s41420-025-02685-5 · 2025 · External reference
Spatial transcriptomic analysis reveals regional transcript changes in early and late stages of rd1 model mice with retinitis pigmentosa
10.3390/ijms241914869 · 2023 · External reference
Identifying Multiomic Signatures of X-Linked Retinoschisis-Derived Retinal Organoids and Mice Harboring Patient-Specific Mutation Using Spatiotemporal Single-Cell Transcriptomics
2024 · External reference
10.1101/2025.08.02.668277
10.1101/2025.08.02.668277 · External reference
Single-cell spatial transcriptomics reveals rewiring of RPE and Müller glia signaling toward photoreceptors following outer segment disruption in Prph2C213Y mice
10.1016/j.nbd.2026.107572 · 2026 · External reference
Differential gene expression in mouse retina related to regional differences in vulnerability to hyperoxia
2010 · External reference
Spatial transcriptomics reveals regionally altered gene expression that drives retinal degeneration. Commun
2025 · External reference
10.1172/jci45627
10.1172/jci45627 · External reference
10.1038/ng2066
10.1038/ng2066 · External reference
10.1167/iovs.61.6.30
10.1167/iovs.61.6.30 · External reference
10.1101/cshperspect.a028274
10.1101/cshperspect.a028274 · External reference
On the Wrong Track: Alterations of Ciliary Transport in Inherited Retinal Dystrophies
10.3389/fcell.2021.623734 · 2021 · External reference
Transcriptional Profiling Identifies Upregulation of Neuroprotective Pathways in Retinitis Pigmentosa
10.3390/ijms22126307 · 2021 · External reference
10.1038/s41467-023-40674-3
10.1038/s41467-023-40674-3 · External reference
10.1038/nn.3032
10.1038/nn.3032 · External reference
Comprehensive single-cell atlas of the mouse retina
10.1016/j.isci.2024.109916 · 2024 · External reference
10.1073/pnas.0509981103
10.1073/pnas.0509981103 · External reference
10.7554/elife.32358
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10.1167/iovs.03-0301
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10.15252/emmm.201505298
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10.3109/02713683.2014.982828
10.3109/02713683.2014.982828 · External reference
10.1371/journal.pone.0120415
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10.1007/s00018-010-0376-9
10.1007/s00018-010-0376-9 · External reference
10.1016/j.cell.2015.03.023
10.1016/j.cell.2015.03.023 · External reference
Monocarboxylate Transporter 1 (MCT1) Mediates Succinate Export in the Retina
2022 · External reference
10.1038/s41419-020-2638-2
10.1038/s41419-020-2638-2 · External reference
Endogenous leukemia inhibitory factor protects photoreceptor cells against light-induced degeneration
2009 · External reference
Rod photoreceptor clearance due to misfolded rhodopsin is linked to a DAMP-immune checkpoint switch
10.1074/jbc.ra120.016053 · 2021 · External reference
Dorsal-Ventral Differences in Retinal Structure in the Pigmented Royal College of Surgeons Model of Retinal Degeneration
10.3389/fncel.2020.553708 · 2021 · External reference
10.1007/s004410050579
10.1007/s004410050579 · External reference
10.1038/s41467-024-45748-4
10.1038/s41467-024-45748-4 · External reference
Measures of Function and Structure to Determine Phenotypic Features, Natural History, and Treatment Outcomes in Inherited Retinal Diseases
10.1146/annurev-vision-032321-091738 · 2021 · External reference
10.1073/pnas.95.12.7103
10.1073/pnas.95.12.7103 · External reference
Variegated yet non-random rod and cone photoreceptor disease patterns in RPGR-ORF15-associated retinal degeneration
10.1093/hmg/ddw361 · 2016 · External reference
Elevating Jak-STAT signaling via SOCS3 deletion sustains photoreceptor viability and visual function in mouse models of retinitis pigmentosa
10.1186/s12964-026-02878-0 · 2026 · External reference
10.1073/pnas.1411248112
10.1073/pnas.1411248112 · External reference
Retinal degeneration is slowed in transgenic rats by AAV-mediated delivery of FGF-2
2000 · External reference
10.1371/journal.pone.0058023
10.1371/journal.pone.0058023 · External reference
Recovery of cone-mediated vision in Lebercilin associated retinal ciliopathy after gene therapy: One-year results of a phase I/II trial
10.1016/j.ymthe.2025.06.035 · 2025 · External reference
10.1038/s41583-024-00806-0
10.1038/s41583-024-00806-0 · External reference
Using Vascular Landmarks to Orient 3D Optical Coherence Tomography Images of the Mouse Eye
10.1002/cpmo.32 · 2017 · External reference
NimbusImage: a cloud-computing platform for image analysis
10.1038/s41592-025-02942-6 · 2026 · External reference
10.1101/2025.04.28.651001
10.1101/2025.04.28.651001 · External reference
10.1007/978-3-319-24574-4_28
10.1007/978-3-319-24574-4_28 · External reference
UMAP: Uniform Manifold Approximation and Projection
10.21105/joss.00861 · 2018 · External reference
10.1038/s41592-019-0619-0
10.1038/s41592-019-0619-0 · External reference
