Research graph
References from NAD⁺ modulation by nicotinamide riboside enhances CD8⁺ T-cell metabolic fitness and effector function during <i>Trypanosoma cruzi</i> infection and improves parasite control. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1016/s0140-6736(23)01787-7
10.1016/s0140-6736(23)01787-7 · External reference
10.1016/j.pt.2019.08.006
10.1016/j.pt.2019.08.006 · External reference
10.1016/j.coi.2009.07.006
10.1016/j.coi.2009.07.006 · External reference
10.4049/jimmunol.144.2.717
10.4049/jimmunol.144.2.717 · External reference
10.1128/iai.74.4.2477-2481.2006
10.1128/iai.74.4.2477-2481.2006 · External reference
10.1016/j.exppara.2010.05.008
10.1016/j.exppara.2010.05.008 · External reference
Relevance of long-lived CD8(+) T effector memory cells for protective immunity elicited by heterologous prime-boost vaccination
2012 · External reference
10.1111/j.1365-3024.2009.01108.x
10.1111/j.1365-3024.2009.01108.x · External reference
10.1086/314889
10.1086/314889 · External reference
10.1016/j.mib.2025.102615
10.1016/j.mib.2025.102615 · External reference
10.1146/annurev-immunol-042617-053019
10.1146/annurev-immunol-042617-053019 · External reference
Metabolic programs tailor T cell immunity in viral infection, cancer, and aging
10.1016/j.cmet.2022.02.003 · 2022 · External reference
10.1016/j.cell.2013.05.016
10.1016/j.cell.2013.05.016 · External reference
10.1038/s41577-019-0203-y
10.1038/s41577-019-0203-y · External reference
10.1016/j.immuni.2012.10.020
10.1016/j.immuni.2012.10.020 · External reference
10.1146/annurev-immunol-101819-082015
10.1146/annurev-immunol-101819-082015 · External reference
10.1016/j.cmet.2017.05.007
10.1016/j.cmet.2017.05.007 · External reference
10.1126/sciadv.adf9522
10.1126/sciadv.adf9522 · External reference
10.1016/j.cmet.2015.05.023
10.1016/j.cmet.2015.05.023 · External reference
Enforced PGC-1alpha expression promotes CD8 T cell fitness, memory formation and antitumor immunity
10.1038/s41423-020-0365-3 · 2021 · External reference
NAD(+) homeostasis in health and disease
10.1038/s42255-019-0161-5 · 2020 · External reference
10.1016/j.cmet.2017.10.006
10.1016/j.cmet.2017.10.006 · External reference
NAD + metabolism and function in innate and adaptive immune cells
10.1186/s12950-025-00457-7 · 2025 · External reference
10.1016/j.celrep.2023.113518
10.1016/j.celrep.2023.113518 · External reference
Age-associated nicotinamide adenine dinucleotide decline drives CAR-T cell failure
10.1038/s43018-025-00982-7 · 2025 · External reference
10.3390/cancers14020323
10.3390/cancers14020323 · External reference
10.1038/s41590-020-0793-3
10.1038/s41590-020-0793-3 · External reference
NAD(+) metabolism: pathophysiologic mechanisms and therapeutic potential
10.1038/s41392-020-00311-7 · 2020 · External reference
10.1016/j.bbrc.2006.05.042
10.1016/j.bbrc.2006.05.042 · External reference
10.1016/j.cmet.2016.05.006
10.1016/j.cmet.2016.05.006 · External reference
10.2337/db12-1139
10.2337/db12-1139 · External reference
10.1038/s41467-018-03421-7
10.1038/s41467-018-03421-7 · External reference
10.3390/cells9071716
10.3390/cells9071716 · External reference
Influence of sexual hormones on Chagas disease
2024 · External reference
10.1007/s004360100474
10.1007/s004360100474 · External reference
10.3389/fimmu.2018.02347
10.3389/fimmu.2018.02347 · External reference
10.1016/j.cmet.2020.11.007
10.1016/j.cmet.2020.11.007 · External reference
10.1038/s41598-018-24676-6
10.1038/s41598-018-24676-6 · External reference
10.1016/j.smim.2016.10.009
10.1016/j.smim.2016.10.009 · External reference
10.1016/s1074-7613(02)00323-0
10.1016/s1074-7613(02)00323-0 · External reference
10.1038/s41590-025-02202-x
10.1038/s41590-025-02202-x · External reference
10.1016/j.celrep.2019.12.014
10.1016/j.celrep.2019.12.014 · External reference
10.1172/jci179561
10.1172/jci179561 · External reference
10.1126/sciadv.abo4271
10.1126/sciadv.abo4271 · External reference
10.1016/j.ymthe.2026.05.026
10.1016/j.ymthe.2026.05.026 · External reference
Nicotinamide Riboside and CD38: Covalent Inhibition and Live-Cell Labeling
10.1021/jacsau.4c00695 · 2024 · External reference
10.3390/nu16213577
10.3390/nu16213577 · External reference
10.1038/s41577-021-00537-8
10.1038/s41577-021-00537-8 · External reference
10.1126/sciadv.adi4862
10.1126/sciadv.adi4862 · External reference
10.1016/j.cmet.2018.02.011
10.1016/j.cmet.2018.02.011 · External reference
10.1038/s41577-024-00996-9
10.1038/s41577-024-00996-9 · External reference
10.1038/s41581-023-00781-2
10.1038/s41581-023-00781-2 · External reference
CD38 inhibitor 78c increases mice lifespan and healthspan in a model of chronological aging
10.1111/acel.13589 · 2022 · External reference
GRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi Infection
10.1371/journal.pntd.0005307 · 2017 · External reference
10.1016/j.actatropica.2007.05.019
10.1016/j.actatropica.2007.05.019 · External reference
Dynamics of tissue repair regulatory T cells and damage in acute Trypanosoma cruzi infection
10.1371/journal.ppat.1012906 · 2025 · External reference
10.1007/978-1-62703-637-5_14
10.1007/978-1-62703-637-5_14 · External reference
