Research graph
References from Engineered CTLA-4 targeting chimeras for targeted protein degradation and immune synapse reprogramming. Local targets link to admitted publications; unresolved targets remain external evidence.
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High-affinity PD-1 molecules deliver improved interaction with PD-L1 and PD-L2
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10.1126/science.aav7062 · External reference
PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways
10.1016/j.immuni.2019.11.003 · 2019 · External reference
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A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression
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Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation
2020 · External reference
RAMIHM generates fully human monoclonal antibodies by rapid mRNA immunization of humanized mice and BCR-seq
10.1016/j.chembiol.2022.12.005 · 2023 · External reference
