Research graph
References from The Smac mimetic drug Xevinapant sensitizes triple negative breast cancer to radiotherapy-induced cell death in a TNFα dependent manner. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1007/s10549-016-4059-6
10.1007/s10549-016-4059-6 · External reference
10.1056/nejmoa2105215
10.1056/nejmoa2105215 · External reference
10.1056/nejmoa1910549
10.1056/nejmoa1910549 · External reference
10.1016/s0140-6736(13)62422-8
10.1016/s0140-6736(13)62422-8 · External reference
10.1016/s0140-6736(11)61629-2
10.1016/s0140-6736(11)61629-2 · External reference
Targeting IAP proteins in combination with radiotherapy
10.1186/s13014-015-0399-3 · 2015 · External reference
10.1016/j.cell.2011.02.013
10.1016/j.cell.2011.02.013 · External reference
10.1038/nrc2889
10.1038/nrc2889 · External reference
Translation control in apoptosis
2012 · External reference
10.1038/nrd3627
10.1038/nrd3627 · External reference
Taking aim with IAP antagonists at triple-negative breast cancer: a moving target no more?
10.1038/s41419-020-2533-x · 2020 · External reference
10.1038/onc.2014.90
10.1038/onc.2014.90 · External reference
Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model
10.18632/oncotarget.13849 · 2017 · External reference
Smac mimetics combined with innate immune stimuli create the perfect cytokine storm to kill tumor cells
10.4161/onci.28541 · 2014 · External reference
10.1593/neo.09436
10.1593/neo.09436 · External reference
10.1158/1535-7163.mct-10-0643
10.1158/1535-7163.mct-10-0643 · External reference
10.1007/s10549-011-1752-3
10.1007/s10549-011-1752-3 · External reference
10.1016/j.ejca.2022.12.015
10.1016/j.ejca.2022.12.015 · External reference
10.1038/s41586-019-1186-3
10.1038/s41586-019-1186-3 · External reference
10.1128/mcb.00546-12
10.1128/mcb.00546-12 · External reference
Apoptosis, p53, and tumor cell sensitivity to anticancer agents
1999 · External reference
Clonogenic assay of cells in vitro
10.1038/nprot.2006.339 · 2006 · External reference
The radiosensitizing activity of the SMAC-mimetic, Debio 1143, is TNFalpha-mediated in head and neck squamous cell carcinoma
10.1016/j.radonc.2015.05.017 · 2015 · External reference
10.1200/jco.2013.52.3993
10.1200/jco.2013.52.3993 · External reference
10.1158/0008-5472.sabcs13-pd5-7
10.1158/0008-5472.sabcs13-pd5-7 · External reference
Unresolved reference
External reference
Xevinapant or Placebo Plus Platinum-Based Chemoradiotherapy in Unresected Locally Advanced Squamous Cell Carcinoma of the Head and Neck (TrilynX): A Randomized, Phase III Study
10.1200/jco-25-00272 · 2025 · External reference
