Research graph
References from pH-sensitive binder design with Proton-PottsMPNN. Local targets link to admitted publications; unresolved targets remain external evidence.
The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration
10.1186/s40035-015-0041-1 · 2015 · External reference
10.1158/0008-5472.can-12-2796
10.1158/0008-5472.can-12-2796 · External reference
10.1038/nbt.1691
10.1038/nbt.1691 · External reference
10.1074/jbc.m111.319764
10.1074/jbc.m111.319764 · External reference
10.1038/s41586-020-2545-9
10.1038/s41586-020-2545-9 · External reference
CYpHER: catalytic extracellular targeted protein degradation with high potency and durable effect
10.1038/s41467-024-52975-2 · 2024 · External reference
10.1101/2025.01.12.632472
10.1101/2025.01.12.632472 · External reference
Improved therapeutic index of an acidic pH-selective antibody
10.1080/19420862.2021.2024642 · 2022 · External reference
VISTA checkpoint inhibition by pH-selective antibody SNS-101 with optimized safety and pharmacokinetic profiles enhances PD-1 response
10.1038/s41467-024-47256-x · 2024 · External reference
10.1126/science.aav7897
10.1126/science.aav7897 · External reference
10.1101/2025.09.29.678932
10.1101/2025.09.29.678932 · External reference
10.1002/pro.696
10.1002/pro.696 · External reference
10.4161/19420862.2014.985993
10.4161/19420862.2014.985993 · External reference
A stepwise mutagenesis approach using histidine and acidic amino acid to engineer highly pH-dependent protein switches
10.1007/s13205-021-03079-x · 2022 · External reference
10.1126/science.add2187
10.1126/science.add2187 · External reference
10.1016/j.bpj.2012.06.044
10.1016/j.bpj.2012.06.044 · External reference
10.1016/j.jmb.2009.03.039
10.1016/j.jmb.2009.03.039 · External reference
Molecular determinants of the pKa values of Asp and Glu residues in staphylococcal nuclease
10.1002/prot.22470 · 2009 · External reference
10.1073/pnas.2535494123
10.1073/pnas.2535494123 · External reference
Unresolved reference
External reference
10.1093/database/baz024
10.1093/database/baz024 · External reference
Propka3: Consistent treatment of internal and surface residues in empirical p ¡i¿k¡/i¿ ¡sub¿a¡/sub¿ predictions
10.1021/ct100578z · 2011 · External reference
10.1038/s41586-023-06328-6
10.1038/s41586-023-06328-6 · External reference
10.1093/nar/gkaa981
10.1093/nar/gkaa981 · External reference
10.1101/2025.09.18.676967
10.1101/2025.09.18.676967 · External reference
10.1101/2025.08.14.670059
10.1101/2025.08.14.670059 · External reference
One-shot design of functional protein binders with BindCraft
10.1038/s41586-025-09429-6 · 2025 · External reference
10.1101/2025.11.20.689494
10.1101/2025.11.20.689494 · External reference
10.1101/2025.06.14.659707
10.1101/2025.06.14.659707 · External reference
10.1101/2025.08.14.670328
10.1101/2025.08.14.670328 · External reference
10.1006/jmbi.1994.1334
10.1006/jmbi.1994.1334 · External reference
10.1038/nbt.3988
10.1038/nbt.3988 · External reference
10.1093/nar/gkab1061
10.1093/nar/gkab1061 · External reference
10.1093/bioinformatics/btad424
10.1093/bioinformatics/btad424 · External reference
ColabFold: making protein folding accessible to all
10.1038/s41592-022-01488-1 · 2022 · External reference
10.1186/s13059-019-1662-y
10.1186/s13059-019-1662-y · External reference
