Research graph
References from Methylation-defined tumour subgroups guide recognition of genetic predisposition in Wilms tumour. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1056/nejmoa1508054
10.1056/nejmoa1508054 · External reference
10.1038/nature25480
10.1038/nature25480 · External reference
Assessment of Cancer Predisposition Syndromes in a National Cohort of Children With a Neoplasm
10.1001/jamanetworkopen.2022.54157 · 2023 · External reference
Comparison of clinical selection-based genetic testing with phenotype-agnostic extensive germline sequencing to diagnose genetic predisposition in children with cancer: a prospective diagnostic study
10.1016/s2352-4642(24)00144-5 · 2024 · External reference
Malformations, genetic abnormalities, and wilms tumor
10.1002/pbc.24709 · 2014 · External reference
High incidence of malformation syndromes in a series of 1,073 children with cancer
10.1002/ajmg.a.30603 · 2005 · External reference
Frequency of WT1 and 11p15 constitutional aberrations and phenotypic correlation in childhood Wilms tumour patients
10.1016/j.ejca.2012.06.008 · 2012 · External reference
Prevalence of (Epi)genetic Predisposing Factors in a 5-Year Unselected National Wilms Tumor Cohort: A Comprehensive Clinical and Genomic Characterization
10.1200/jco.21.02510 · 2022 · External reference
10.1136/jmg-2022-108982
10.1136/jmg-2022-108982 · External reference
10.1002/cncr.32907
10.1002/cncr.32907 · External reference
10.1126/science.aax1323
10.1126/science.aax1323 · External reference
10.1158/2159-8290.cd-24-0878
10.1158/2159-8290.cd-24-0878 · External reference
Embryonic Kidney Development, Stem Cells and the Origin of Wilms Tumor
10.3390/genes12020318 · 2021 · External reference
Mutation and Cancer: A Model for Wilms’ Tumor of the Kidney
1972 · External reference
Clinically Relevant Subsets Identified by Gene Expression Patterns Support a Revised Ontogenic Model of Wilms Tumor: A Children’s Oncology Group Study
2012 · External reference
Clinically and biologically relevant subgroups of Wilms tumour defined by genomic and epigenomic analyses
10.1038/s41416-020-01102-1 · 2021 · External reference
10.1038/s41581-019-0112-0
10.1038/s41581-019-0112-0 · External reference
Molecular Characterization Reveals Subclasses of 1q Gain in Intermediate Risk Wilms Tumors
10.3390/cancers14194872 · 2022 · External reference
Unresolved reference
External reference
10.1038/gim.2015.30
10.1038/gim.2015.30 · External reference
Unresolved reference
External reference
10.1186/s13059-016-0974-4
10.1186/s13059-016-0974-4 · External reference
10.1038/s41586-020-2308-7
10.1038/s41586-020-2308-7 · External reference
10.1093/nar/gky1016
10.1093/nar/gky1016 · External reference
10.1016/j.cell.2018.12.015
10.1016/j.cell.2018.12.015 · External reference
10.1158/0008-5472.can-17-0337
10.1158/0008-5472.can-17-0337 · External reference
Complex structural variation is prevalent and highly pathogenic in pediatric solid tumors
10.1016/j.xgen.2024.100675 · 2024 · External reference
10.5281/zenodo.13379929
10.5281/zenodo.13379929 · External reference
10.1093/bioinformatics/btv710
10.1093/bioinformatics/btv710 · External reference
10.1101/2024.05.30.596713
10.1101/2024.05.30.596713 · External reference
Unresolved reference
External reference
11p15 Epimutations in Pediatric Embryonic Tumors: Insights from a Methylome Analysis
10.3390/cancers15174256 · 2023 · External reference
10.1016/j.gene.2008.09.021
10.1016/j.gene.2008.09.021 · External reference
M&M: an RNA-seq based pan-cancer classifier for paediatric tumours
10.1016/j.ebiom.2024.105506 · 2025 · External reference
10.18129/b9.bioc.sesame
10.18129/b9.bioc.sesame · External reference
10.1093/nar/gky691
10.1093/nar/gky691 · External reference
10.1093/bioinformatics/btu049
10.1093/bioinformatics/btu049 · External reference
10.18129/b9.bioc.minfi
10.18129/b9.bioc.minfi · External reference
10.18129/b9.bioc.limma
10.18129/b9.bioc.limma · External reference
10.1093/nar/gkv007
10.1093/nar/gkv007 · External reference
10.18129/b9.bioc.sva
10.18129/b9.bioc.sva · External reference
10.1093/bioinformatics/bts034
10.1093/bioinformatics/bts034 · External reference
10.18129/b9.bioc.consensusclusterplus
10.18129/b9.bioc.consensusclusterplus · External reference
10.1093/bioinformatics/btq170
10.1093/bioinformatics/btq170 · External reference
10.1023/a:1010933404324
10.1023/a:1010933404324 · External reference
10.48550/arxiv.1802.03426
10.48550/arxiv.1802.03426 · External reference
10.18129/b9.bioc.complexheatmap
10.18129/b9.bioc.complexheatmap · External reference
Complex heatmap visualization
10.1002/imt2.43 · 2022 · External reference
10.32614/cran.package.ggplot2
10.32614/cran.package.ggplot2 · External reference
10.18129/b9.bioc.deseq2
10.18129/b9.bioc.deseq2 · External reference
10.1186/s13059-014-0550-8
10.1186/s13059-014-0550-8 · External reference
Conumee 2.0: enhanced copy-number variation analysis from DNA methylation arrays for humans and mice
10.1093/bioinformatics/btae029 · 2024 · External reference
Constitutional and somatic methylation status of DMRH19 and KvDMR in Wilms tumor patients
10.1590/s1415-47572012005000073 · 2012 · External reference
10.1016/s0002-9440(10)63246-4
10.1016/s0002-9440(10)63246-4 · External reference
Genetic and epigenetic features of bilateral Wilms tumor predisposition in patients from the Children’s Oncology Group AREN18B5-Q
10.1038/s41467-023-43730-0 · 2023 · External reference
10.1186/s13073-025-01482-0
10.1186/s13073-025-01482-0 · External reference
10.1136/jcp.2006.043083
10.1136/jcp.2006.043083 · External reference
TRIM28 haploinsufficiency predisposes to Wilms tumor
10.1002/ijc.32167 · 2019 · External reference
10.1002/path.5639
10.1002/path.5639 · External reference
