Research graph
References from The ammonia–senescence ratchet drives an adaptation–senescence– ammonioptosis transition in liver cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
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Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability
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Tumor-produced ammonia is metabolized by regulatory T cells to further impede anti-tumor immunity
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Ammonia-induced lysosomal and mitochondrial damage causes cell death of effector CD8+ T cells
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Targeted liposomes sensitize plastic melanoma to ferroptosis via senescence induction and coenzyme depletion
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