Research graph
References from Glyceraldehyde-3-phosphate sensing by SOS1 and RAS sustains a self-reinforcing oncogenic metabolic-signaling circuit. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1038/s41568-021-00375-9
10.1038/s41568-021-00375-9 · External reference
The Metabolic Landscape of RAS-Driven Cancers from biology to therapy
10.1038/s43018-021-00184-x · 2021 · External reference
Oncogenic RAS commandeers amino acid sensing machinery to aberrantly activate mTORC1 in multiple myeloma
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10.1038/s41586-019-1832-9
10.1038/s41586-019-1832-9 · External reference
KRAS4A promotes oligomerization of hexokinase 1 on mitochondria
10.1016/j.celrep.2026.117392 · 2026 · External reference
10.1158/0008-5472.can-21-3629
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MAZ promotes tumor proliferation and immune evasion in lung adenocarcinoma
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10.1038/s41467-026-72922-7
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Dependence of NPPS creates a targetable vulnerability in RAS-mutant cancers
10.1038/s41401-024-01409-2 · 2025 · External reference
10.1038/s41580-022-00572-w
10.1038/s41580-022-00572-w · External reference
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10.1038/s41467-017-01019-z · External reference
Dihydroxyacetone phosphate signals glucose availability to mTORC1
10.1038/s42255-020-0250-5 · 2020 · External reference
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
10.1038/s41586-025-09745-x · 2026 · External reference
10.1038/s41588-021-01008-5
10.1038/s41588-021-01008-5 · External reference
10.1074/jbc.ra117.000333
10.1074/jbc.ra117.000333 · External reference
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10.1038/s41586-024-08283-2
10.1038/s41586-024-08283-2 · External reference
It took a long, long time: Ras and the race to cure cancer
10.1016/j.cell.2024.02.042 · 2024 · External reference
10.1073/pnas.2319492121
10.1073/pnas.2319492121 · External reference
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10.1038/s41571-022-00671-9 · External reference
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10.1152/ajpendo.00082.2018 · External reference
10.1016/j.cell.2026.03.031
10.1016/j.cell.2026.03.031 · External reference
