Research graph
References from THERAPY RESISTANCE IN MELANOMA DRIVES CILIOGENESIS AND GLUTAMINE/ASPARTATE METABOLISM DEPENDENCY. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1038/s41586-020-1943-3
10.1038/s41586-020-1943-3 · External reference
10.1158/1078-0432.ccr-19-0253
10.1158/1078-0432.ccr-19-0253 · External reference
10.1038/75556
10.1038/75556 · External reference
10.1016/j.molonc.2015.08.003
10.1016/j.molonc.2015.08.003 · External reference
10.1101/cshperspect.a028175
10.1101/cshperspect.a028175 · External reference
Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study
2009 · External reference
10.1016/j.molcel.2026.02.004
10.1016/j.molcel.2026.02.004 · External reference
10.1093/nar/gkw907
10.1093/nar/gkw907 · External reference
Prdx1 promotes the loss of primary cilia in esophageal squamous cell carcinoma
10.1186/s12885-020-06898-y · 2020 · External reference
10.1038/s41418-020-00713-8
10.1038/s41418-020-00713-8 · External reference
Active Ribosome Profiling with RiboLace
10.1016/j.celrep.2018.09.084 · 2018 · External reference
10.1038/s41388-025-03416-x
10.1038/s41388-025-03416-x · External reference
10.18632/oncotarget.1420
10.18632/oncotarget.1420 · External reference
Glutamine Metabolism in Health and Diseases
10.1002/mco2.71035 · 2026 · External reference
10.1038/s41556-024-01439-2
10.1038/s41556-024-01439-2 · External reference
10.1016/j.cell.2023.01.038
10.1016/j.cell.2023.01.038 · External reference
10.3791/51455-v
10.3791/51455-v · External reference
10.18632/oncotarget.965
10.18632/oncotarget.965 · External reference
10.1038/nm.2020
10.1038/nm.2020 · External reference
10.1016/j.cell.2025.08.039
10.1016/j.cell.2025.08.039 · External reference
10.1016/j.ccr.2013.02.003
10.1016/j.ccr.2013.02.003 · External reference
10.1242/dev.02732
10.1242/dev.02732 · External reference
10.1186/s12967-015-0581-2
10.1186/s12967-015-0581-2 · External reference
10.1016/j.celrep.2018.05.016
10.1016/j.celrep.2018.05.016 · External reference
10.1038/bjc.2014.431
10.1038/bjc.2014.431 · External reference
10.1093/nar/gkac963
10.1093/nar/gkac963 · External reference
10.4161/cc.10.16.17009
10.4161/cc.10.16.17009 · External reference
10.15252/embr.201541922
10.15252/embr.201541922 · External reference
10.1371/journal.pcbi.1006169
10.1371/journal.pcbi.1006169 · External reference
10.1186/s13630-019-0061-z
10.1186/s13630-019-0061-z · External reference
Amino acid metabolism in health and disease
10.1038/s41392-023-01569-3 · 2023 · External reference
10.1038/s41568-018-0023-6
10.1038/s41568-018-0023-6 · External reference
10.1186/s13059-014-0550-8
10.1186/s13059-014-0550-8 · External reference
10.1007/978-3-030-34025-4_11
10.1007/978-3-030-34025-4_11 · External reference
10.1111/pcmr.12498
10.1111/pcmr.12498 · External reference
10.1186/2046-2530-3-7
10.1186/2046-2530-3-7 · External reference
10.1093/nar/gkad1025
10.1093/nar/gkad1025 · External reference
10.1038/s41576-023-00587-9
10.1038/s41576-023-00587-9 · External reference
Emerging roles of the ciliary-mitochondrial axis in cellular homeostasis and neuroprotection
10.1186/s44477-025-00005-w · 2025 · External reference
Hedgehog pathway blockade inhibits melanoma cell growth in vitro and in vivo
10.3390/ph6111429 · 2013 · External reference
Metabolic Regulation and Energy Homeostasis through the Primary Cilium
10.1016/j.cmet.2014.11.019 · 2015 · External reference
10.1093/nar/gkae253
10.1093/nar/gkae253 · External reference
10.1158/2159-8290.cd-13-0440
10.1158/2159-8290.cd-13-0440 · External reference
10.1158/0008-5472.can-07-5838
10.1158/0008-5472.can-07-5838 · External reference
Aspartate in the Brain: A Review
10.1007/s11064-025-04454-3 · 2025 · External reference
Genome engineering using the CRISPR-Cas9 system
10.1038/nprot.2013.143 · 2013 · External reference
10.1038/nrm.2017.60
10.1038/nrm.2017.60 · External reference
10.1093/nar/gkv007
10.1093/nar/gkv007 · External reference
10.1056/nejmoa1412690
10.1056/nejmoa1412690 · External reference
Determinants of resistance and response to melanoma therapy
10.1038/s43018-024-00794-1 · 2024 · External reference
10.1038/s41586-022-04758-2
10.1038/s41586-022-04758-2 · External reference
10.1186/s12964-026-03219-x · Admitted local publication
Metabolic reprogramming in melanoma therapy
10.1038/s41420-025-02617-3 · 2025 · External reference
TORC1 phosphorylates and inhibits the ribosome preservation factor Stm1 to activate dormant ribosomes
10.15252/embj.2022112344 · 2023 · External reference
Loss of primary cilia in melanoma cells is likely independent of proliferation and cell cycle progression
10.1038/jid.2015.22 · 2015 · External reference
10.1073/pnas.0700776104
10.1073/pnas.0700776104 · External reference
Primary cilia sense glutamine availability and respond via asparagine synthetase
10.1038/s42255-023-00754-6 · 2023 · External reference
10.1038/s41556-018-0125-0
10.1038/s41556-018-0125-0 · External reference
10.1038/nature13121
10.1038/nature13121 · External reference
SLC1A3 contributes to L-asparaginase resistance in solid tumors
10.15252/embj.2019102147 · 2019 · External reference
Melanoma Metabolism: Molecular Mechanisms and Therapeutic Implications in Cutaneous Oncology
10.1002/cam4.70386 · 2024 · External reference
10.3389/fmolb.2020.00154
10.3389/fmolb.2020.00154 · External reference
10.1016/j.cell.2012.09.021
10.1016/j.cell.2012.09.021 · External reference
EMT-ciliary signaling in quasi-mesenchymal-stem-like cells drives therapeutic resistance and is a druggable vulnerability in triple-negative breast cancer
2025 · External reference
10.1038/nature11083
10.1038/nature11083 · External reference
10.3389/fcell.2022.927118
10.3389/fcell.2022.927118 · External reference
10.1242/jcs.264187
10.1242/jcs.264187 · External reference
10.1158/2159-8290.cd-13-0631
10.1158/2159-8290.cd-13-0631 · External reference
10.1016/j.cell.2018.04.012
10.1016/j.cell.2018.04.012 · External reference
10.1182/blood-2009-05-224824
10.1182/blood-2009-05-224824 · External reference
An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis
10.1126/sciadv.abf6063 · 2021 · External reference
10.1158/1055-9965.epi-18-0243
10.1158/1055-9965.epi-18-0243 · External reference
10.1089/omi.2011.0118
10.1089/omi.2011.0118 · External reference
10.1093/bioinformatics/bty895
10.1093/bioinformatics/bty895 · External reference
EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation
10.1016/j.ccell.2018.06.001 · 2018 · External reference
