References

Classic reaction kinetics can explain complex patterns of antibiotic action

10.1126/scitranslmed.aaa8760 · 2015 · External reference

The spectrum of drug susceptibility in mycobacteria

10.1128/microbiolspec.mgm2-0031-2013 · 2014 · External reference

New unstable variants of green fluorescent protein for studies of transient gene expression in bacteria

10.1128/aem.64.6.2240-2246.1998 · 1998 · External reference

Distinguishing between resistance, tolerance and persistence to antibiotic treatment

10.1038/nrmicro.2016.34 · 2016 · External reference

Forward genetics reveals a gatC-gatA fusion polypeptide causes mistranslation and rifampicin tolerance in Mycobacterium smegmatis

10.3389/fmicb.2020.577756 · 2020 · External reference

Kasugamycin potentiates rifampicin and limits emergence of resistance in Mycobacterium tuberculosis by specifically decreasing mycobacterial mistranslation

10.7554/elife.36782 · 2018 · External reference

Measurement of specific mycobacterial mistranslation rates with gain-of-function reporter systems

10.3791/59453 · 2019 · External reference

Selective translation by alternative bacterial ribosomes

10.1073/pnas.2009607117 · 2020 · External reference

Natural homolog of tRNA synthetase editing domain rescues conditional lethality caused by mistranslation

10.1074/jbc.m805943200 · 2008 · External reference

Distinct ways of G:U recognition by conserved tRNA binding motifs

10.1073/pnas.1807109115 · 2018 · External reference

Glu-tRNAGln amidotransferase: a novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation

10.1073/pnas.94.22.11819 · 1997 · External reference

Amino acid specificity in translation

10.1016/j.tibs.2005.10.006 · 2005 · External reference

Binding of misacylated tRNAs to the ribosomal A site

10.1261/rna.2130505 · 2005 · External reference

Pathways to specialized ribosomes: the brussels lecture

10.1016/j.jmb.2015.12.021 · 2016 · External reference

The evolutionary consequences of erroneous protein synthesis

10.1038/nrg2662 · 2009 · External reference

Natural amino acids do not require their native tRNAs for efficient selection by the ribosome

10.1038/nchembio.255 · 2009 · External reference

Ribosome stoichiometry: from form to function

10.1016/j.tibs.2018.10.009 · 2019 · External reference

Errors during gene expression: single-cell heterogeneity, stress resistance, and microbe-host interactions

10.1128/mbio.01018-18 · 2018 · External reference

Protein mistranslation protects bacteria against oxidative stress

10.1093/nar/gku1404 · 2015 · External reference

Heterogeneity of stop codon readthrough in single bacterial cells and implications for population fitness

10.1016/j.molcel.2017.07.010 · 2017 · External reference

Optimal translational fidelity is critical for Salmonella virulence and host interactions

10.1093/nar/gkz229 · 2019 · External reference

Targeting phenotypically tolerant Mycobacterium tuberculosis

10.1128/microbiolspec.tbtb2-0031-2016 · 2017 · External reference

Clinically prevalent mutations in Mycobacterium tuberculosis alter propionate metabolism and mediate multidrug tolerance

10.1038/s41564-018-0218-3 · 2018 · External reference

A simple structural feature is a major determinant of the identity of a transfer RNA

10.1038/333140a0 · 1988 · External reference

Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance

10.1073/pnas.1317580111 · 2014 · External reference

Rate and accuracy of bacterial protein synthesis revisited

10.1016/j.mib.2008.02.015 · 2008 · External reference

Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death

10.1016/j.cell.2008.09.038 · 2008 · External reference

The frequency of translational misreading errors in E. coli is largely determined by tRNA competition

10.1261/rna.294907 · 2007 · External reference

Endogenous rRNA sequence variation can regulate stress response gene expression and phenotype

10.1016/j.celrep.2018.08.093 · 2018 · External reference

Uniform binding of aminoacyl-tRNAs to elongation factor Tu by thermodynamic compensation

10.1126/science.1064242 · 2001 · External reference

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration

10.1038/nature05096 · 2006 · External reference

Promiscuous methionyl-tRNA synthetase mediates adaptive mistranslation to protect cells against oxidative stress

10.1242/jcs.152470 · 2014 · External reference

Translational misreading in Mycobacterium smegmatis increases in stationary phase

10.1016/j.tube.2015.09.010 · 2015 · External reference

Naturally occurring aminoacyl-tRNA synthetases editing-domain mutations that cause mistranslation in Mycoplasma parasites

10.1073/pnas.1016460108 · 2011 · External reference

Clinically relevant mutations of mycobacterial GatCAB inform regulation of translational fidelity

10.1128/mbio.01100-21 · 2021 · External reference

Protein aggregation caused by aminoglycoside action is prevented by a hydrogen peroxide scavenger

10.1016/j.molcel.2012.10.001 · 2012 · External reference

Genetic code flexibility in microorganisms: novel mechanisms and impact on physiology

10.1038/nrmicro3568 · 2015 · External reference

Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy

10.1073/pnas.1420196111 · 2014 · External reference

Candida albicans CUG mistranslation is a mechanism to create cell surface variation

10.1128/mbio.00285-13 · 2013 · External reference

Translational fidelity and mistranslation in the cellular response to stress

10.1038/nmicrobiol.2017.117 · 2017 · External reference

Elongation factor-Tu can repetitively engage aminoacyl-tRNA within the ribosome during the proofreading stage of tRNA selection

10.1073/pnas.1904469117 · 2020 · External reference

Innate immune and chemically triggered oxidative stress modifies translational fidelity

10.1038/nature08576 · 2009 · External reference

Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria

10.1111/j.1365-2958.2006.05585.x · 2007 · External reference

Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome

10.1093/emboj/17.24.7490 · 1998 · External reference

Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression

10.1126/sciadv.aao0665 · 2018 · External reference

Indirect tRNA aminoacylation during accurate translation and phenotypic mistranslation

10.1016/j.cbpa.2017.10.009 · 2017 · External reference

Cell-specific differences in the requirements for translation quality control

10.1073/pnas.0909640107 · 2010 · External reference

Protein mistranslation: friend or foe?

10.1016/j.tibs.2014.06.002 · 2014 · External reference

Temporal and intrinsic factors of rifampicin tolerance in mycobacteria

10.1073/pnas.1600372113 · 2016 · External reference

Quality control despite mistranslation caused by an ambiguous genetic code

10.1073/pnas.0809179105 · 2008 · External reference

Aminoacyl-tRNA synthetases

10.1261/rna.071720.119 · 2020 · External reference

Phase variation in Mycobacterium tuberculosis glpK produces transiently heritable drug tolerance

10.1073/pnas.1907631116 · 2019 · External reference

Structural analysis of kasugamycin inhibition of translation

10.1038/nsmb1150 · 2006 · External reference

Temperature dependent mistranslation in a hyperthermophile adapts proteins to lower temperatures

10.1093/nar/gkv1379 · 2016 · External reference

Global tRNA misacylation induced by anaerobiosis and antibiotic exposure broadly increases stress resistance in Escherichia coli

10.1093/nar/gkw856 · 2016 · External reference

Function and origin of mistranslation in distinct cellular contexts

10.1080/10409238.2016.1274284 · 2017 · External reference

On the evolution of the tRNA-dependent amidotransferases, GatCAB and GatDE

10.1016/j.jmb.2008.01.016 · 2008 · External reference

Tuning the ribosome: the influence of rRNA modification on eukaryotic ribosome biogenesis and function

10.1080/15476286.2016.1259781 · 2017 · External reference

Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis

10.1111/j.1365-2958.1990.tb02040.x · 1990 · External reference

The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity

10.1038/nmicrobiol.2016.147 · 2016 · External reference

Alanyl-tRNA synthetase crystal structure and design for acceptor-stem recognition

10.1016/s1097-2765(04)00126-1 · 2004 · External reference

Translational regulation of environmental adaptation in bacteria

10.1074/jbc.rev120.012742 · 2020 · External reference

Increased translational fidelity caused by the antibiotic kasugamycin and ribosomal ambiguity in mutants harbouring the ksgA gene

10.1016/0014-5793(84)80994-1 · 1984 · External reference

Exclusive use of trans-editing domains prevents proline mistranslation

10.1074/jbc.m113.467795 · 2013 · External reference

Most-Probable number based minimum duration of killing assay for determining the spectrum of rifampicin susceptibility in clinical M. tuberculosis Isolates

10.1101/2020.06.29.179200 · 2020 · External reference

Enhanced respiration prevents drug tolerance and drug resistance in Mycobacterium tuberculosis

10.1073/pnas.1704376114 · 2017 · External reference

Dynamic persistence of antibiotic-stressed mycobacteria

10.1126/science.1229858 · 2013 · External reference

Clinically relevant mutations in mycobacterial LepA cause rifampicin-specific phenotypic resistance

10.1038/s41598-020-65308-2 · 2020 · External reference

Evolutionary optimization of speed and accuracy of decoding on the ribosome

10.1098/rstb.2011.0138 · 2011 · External reference

Functional role of methylation of G518 of the 16S rRNA 530 loop by GidB in Mycobacterium tuberculosis

10.1128/aac.00905-13 · 2013 · External reference

Fidelity at the molecular level: lessons from protein synthesis

10.1016/j.cell.2009.01.036 · 2009 · External reference

Quality control by the ribosome following peptide bond formation

10.1038/nature07582 · 2009 · External reference

HspX promotes the polar localization of mycobacterial protein aggregates

10.1038/s41598-019-51132-w · 2019 · External reference

Rifampicin can induce antibiotic tolerance in mycobacteria via paradoxical changes in rpoB transcription

10.1038/s41467-018-06667-3 · 2018 · External reference

HWS19 strain gidB mutant mycobacterial ribosome

10.2210/pdb9b1x/pdb · 2024 · External reference

HWS19 strain WT mycobacterial ribosome

10.2210/pdb9b1w/pdb · 2024 · External reference

WT strain gidB mutant mycobacterial ribosome

10.2210/pdb9b24/pdb · 2024 · External reference

WT strain WT mycobacterial ribosome

10.2210/pdb9b1y/pdb · 2024 · External reference