Research graph
References from DGKα and ζ deficiency causes regulatory T-cell dysregulation, destabilization, and conversion to pathogenic T-follicular helper cells to trigger IgG1-predominant autoimmunity. Local targets link to admitted publications; unresolved targets remain external evidence.
B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity
10.1084/jem.20170580 · 2017 · External reference
Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response
10.1016/j.immuni.2013.10.016 · 2013 · External reference
SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling
10.4049/jimmunol.1002476 · 2011 · External reference
Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation
10.1016/j.immuni.2012.02.012 · 2012 · External reference
A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells
10.4049/jimmunol.181.1.225 · 2008 · External reference
Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency
10.1016/j.immuni.2012.03.020 · 2012 · External reference
Treg cells-the next frontier of cell therapy
10.1126/science.aau2688 · 2018 · External reference
PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21
10.1172/jci.insight.130062 · 2019 · External reference
Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection
10.1038/ni.3837 · 2017 · External reference
CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner
10.1126/science.1172702 · 2009 · External reference
Murine regulatory T cells contain hyperproliferative and death-prone subsets with differential ICOS expression
10.4049/jimmunol.1102448 · 2012 · External reference
Diacylglycerol kinases in T cell tolerance and effector function
10.3389/fcell.2016.00130 · 2016 · External reference
The lupus susceptibility gene Pbx1 regulates the balance between follicular helper T cell and regulatory T cell differentiation
10.4049/jimmunol.1502283 · 2016 · External reference
Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
10.1038/nm.2426 · 2011 · External reference
A brief history of T cell help to B cells
10.1038/nri3803 · 2015 · External reference
Germinal centers and autoimmune disease in humans and mice
10.1038/icb.2016.78 · 2016 · External reference
TCR signaling events are required for maintaining CD4 regulatory T cell numbers and suppressive capacities in the periphery
10.4049/jimmunol.1400477 · 2014 · External reference
Pim-2 kinase influences regulatory T cell function and stability by mediating Foxp3 protein N-terminal phosphorylation
10.1074/jbc.m115.638221 · 2015 · External reference
The chromatin-modifying Enzyme Ezh2 is critical for the maintenance of regulatory T cell identity after activation
10.1016/j.immuni.2015.01.007 · 2015 · External reference
Circulating CXCR5−PD-1hi peripheral T helper cells are associated with progression to type 1 diabetes
10.1007/s00125-019-4936-8 · 2019 · External reference
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
10.1038/ni904 · 2003 · External reference
Deficiency in T follicular regulatory cells promotes autoimmunity
10.1084/jem.20170901 · 2018 · External reference
Negative regulation of mTOR activation by diacylglycerol kinases
10.1182/blood-2010-08-300731 · 2011 · External reference
Identification of a T follicular helper cell subset that drives anaphylactic IgE
10.1126/science.aaw6433 · 2019 · External reference
Synergistic control of T cell development and tumor suppression by diacylglycerol kinase alpha and zeta
10.1073/pnas.0711856105 · 2008 · External reference
BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms
10.1084/jem.20141380 · 2015 · External reference
Control of regulatory T cell development by the transcription factor Foxp3
10.1126/science.1079490 · 2003 · External reference
Lineage stability and phenotypic plasticity of Foxp3(+) regulatory T cells
10.1111/imr.12175 · 2014 · External reference
FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program
10.1084/jem.20181134 · 2019 · External reference
Expression of Foxp3 by T follicular helper cells in end-stage germinal centers
10.1126/science.abe5146 · 2021 · External reference
OX40 Ligand Contributes to human lupus pathogenesis by promoting T follicular helper response
10.1016/j.immuni.2015.05.012 · 2015 · External reference
Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses
10.1016/j.immuni.2014.02.012 · 2014 · External reference
The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling
10.1126/scisignal.2004373 · 2013 · External reference
CRISPR/Cas9-mediated knockout of DGK improves antitumor activities of human T cells
10.1158/0008-5472.can-18-0030 · 2018 · External reference
Foxo transcription factors control regulatory T cell development and function
10.1016/j.immuni.2010.12.002 · 2010 · External reference
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis
10.1038/nm.3432 · 2014 · External reference
Developmental bifurcation of human T follicular regulatory cells
10.1126/sciimmunol.abd8411 · 2021 · External reference
Continuous requirement for the TCR in regulatory T cell function
10.1038/ni.3004 · 2014 · External reference
Stability and function of regulatory T cells expressing the transcription factor T-bet
10.1038/nature22360 · 2017 · External reference
Mammalian Sterile 20-like Kinase 1 (Mst1) enhances the stability of forkhead box P3 (Foxp3) and the function of regulatory T cells by modulating Foxp3 Acetylation
10.1074/jbc.m115.668442 · 2015 · External reference
Tumor progression Locus 2 (Tpl2) activates the mammalian target of Rapamycin (mTOR) pathway, inhibits Forkhead Box P3 (FoxP3) expression, and limits regulatory T Cell (Treg) immunosuppressive functions
10.1074/jbc.m116.718783 · 2016 · External reference
T cell receptor signalling in the control of regulatory T cell differentiation and function
10.1038/nri.2016.26 · 2016 · External reference
Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development
10.1038/nature12910 · 2014 · External reference
Poly(ADP-ribosyl)ation of FOXP3 protein mediated by PARP-1 regulates the function of regulatory T cells
10.1074/jbc.a115.661611 · 2016 · External reference
Diacylglycerol kinase control of protein kinase C
10.1042/bcj20180620 · 2019 · External reference
Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells
10.1016/j.immuni.2011.12.012 · 2012 · External reference
Foxp3 protein stability is regulated by cyclin-dependent kinase 2*
10.1074/jbc.m113.467704 · 2013 · External reference
Disruption of diacylglycerol metabolism impairs the induction of T cell anergy
10.1038/ni1400 · 2006 · External reference
Graded diacylglycerol kinases α and ζ activities ensure mucosal-associated invariant T-cell development in mice
10.1002/eji.201948289 · 2020 · External reference
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
10.1038/nature20810 · 2017 · External reference
Enhanced effector responses in activated CD8+ T cells deficient in diacylglycerol kinases
10.1158/0008-5472.can-12-3874 · 2013 · External reference
T(fr) cells lack IL-2Ralpha but express decoy IL-1R2 and IL-1Ra and suppress the IL-1-dependent activation of T(fh) cells
10.1126/sciimmunol.aan0368 · 2017 · External reference
BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis
10.1038/nature12199 · 2013 · External reference
Stability of the regulatory T cell lineage in vivo
10.1126/science.1191996 · 2010 · External reference
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1
10.1126/scitranslmed.aad1565 · 2016 · External reference
T follicular regulatory cells
10.1111/imr.12411 · 2016 · External reference
Regulatory T cells and immune tolerance
10.1016/j.cell.2008.05.009 · 2008 · External reference
The plasticity and stability of regulatory T cells
10.1038/nri3464 · 2013 · External reference
Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification
10.1016/j.cell.2012.06.053 · 2012 · External reference
Diacylglycerol kinase ζ limits the generation of natural regulatory T cells
10.1126/scisignal.2004411 · 2013 · External reference
CD23 surface density on B cells is associated with IgE levels and determines IgE-facilitated allergen uptake, as well as activation of allergen-specific T cells
10.1016/j.jaci.2016.03.042 · 2017 · External reference
Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells
10.1126/sciimmunol.adf6717 · 2023 · External reference
Tight regulation of diacylglycerol-mediated signaling is critical for proper invariant NKT cell development
10.4049/jimmunol.1100495 · 2011 · External reference
The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6
10.15252/embj.201591459 · 2016 · External reference
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
10.1038/ni1160 · 2005 · External reference
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state
10.1093/intimm/10.12.1969 · 1998 · External reference
PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance
10.1084/jem.20182232 · 2021 · External reference
Essential and non-overlapping IL-2Rα-dependent processes for thymic development and peripheral homeostasis of regulatory T cells
10.1038/s41467-019-08960-1 · 2019 · External reference
Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer’s patches
10.1126/science.1169152 · 2009 · External reference
Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers
10.1084/jem.190.8.1115 · 1999 · External reference
An essential role of the transcription factor GATA-3 for the function of regulatory T cells
10.1016/j.immuni.2011.08.012 · 2011 · External reference
BATF regulates T regulatory cell functional specification and fitness of triglyceride metabolism in restraining allergic responses
10.4049/jimmunol.2001184 · 2021 · External reference
Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses
10.7554/elife.17936 · 2016 · External reference
Unexpected positive control of NFκB and miR-155 by DGKα and ζ ensures effector and memory CD8+ T cell differentiation
10.18632/oncotarget.8164 · 2016 · External reference
DGK α and ζ activities control TH1 and TH17 cell differentiation
10.3389/fimmu.2019.03048 · 2019 · External reference
Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases
10.1038/s41423-020-00529-z · 2021 · External reference
Control of Foxp3 stability through modulation of TET activity
10.1084/jem.20151438 · 2016 · External reference
mTORC1 and mTORC2 kinase signaling and glucose metabolism drive follicular helper T Cell differentiation
10.1016/j.immuni.2016.08.017 · 2016 · External reference
T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alpha
10.1038/ni1394 · 2006 · External reference
B cells drive autoimmunity in mice with CD28-deficient regulatory T cells
10.4049/jimmunol.1700409 · 2017 · External reference
Regulation of intrinsic and bystander T follicular helper cell differentiation and autoimmunity by Tsc1
10.3389/fimmu.2021.620437 · 2021 · External reference
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
10.1038/nature07674 · 2009 · External reference
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
10.1038/nature08750 · 2010 · External reference
Enhanced T cell responses due to diacylglycerol kinase zeta deficiency
10.1038/ni958 · 2003 · External reference
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
10.1038/ni.1774 · 2009 · External reference
Synergistic Role of DGKalpha and zeta in Regulatory T cell function, stability, and pathogenecity
2025 · External reference
Graded diacylglycerol kinases α and ζ activities ensure mucosal-associated invariant T-cell development in mice
10.1002/eji.201948289 · ExternalCitation · doi-reference
Circulating CXCR5−PD-1hi peripheral T helper cells are associated with progression to type 1 diabetes
10.1007/s00125-019-4936-8 · ExternalCitation · doi-reference
Regulatory T cells and immune tolerance
10.1016/j.cell.2008.05.009 · ExternalCitation · doi-reference
Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification
10.1016/j.cell.2012.06.053 · ExternalCitation · doi-reference
Foxo transcription factors control regulatory T cell development and function
10.1016/j.immuni.2010.12.002 · ExternalCitation · doi-reference
An essential role of the transcription factor GATA-3 for the function of regulatory T cells
10.1016/j.immuni.2011.08.012 · ExternalCitation · doi-reference
Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells
10.1016/j.immuni.2011.12.012 · ExternalCitation · doi-reference
Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation
10.1016/j.immuni.2012.02.012 · ExternalCitation · doi-reference
Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency
10.1016/j.immuni.2012.03.020 · ExternalCitation · doi-reference
Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response
10.1016/j.immuni.2013.10.016 · ExternalCitation · doi-reference
Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses
10.1016/j.immuni.2014.02.012 · ExternalCitation · doi-reference
The chromatin-modifying Enzyme Ezh2 is critical for the maintenance of regulatory T cell identity after activation
10.1016/j.immuni.2015.01.007 · ExternalCitation · doi-reference
OX40 Ligand Contributes to human lupus pathogenesis by promoting T follicular helper response
10.1016/j.immuni.2015.05.012 · ExternalCitation · doi-reference
mTORC1 and mTORC2 kinase signaling and glucose metabolism drive follicular helper T Cell differentiation
10.1016/j.immuni.2016.08.017 · ExternalCitation · doi-reference
CD23 surface density on B cells is associated with IgE levels and determines IgE-facilitated allergen uptake, as well as activation of allergen-specific T cells
10.1016/j.jaci.2016.03.042 · ExternalCitation · doi-reference
Germinal centers and autoimmune disease in humans and mice
10.1038/icb.2016.78 · ExternalCitation · doi-reference
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
10.1038/nature07674 · ExternalCitation · doi-reference
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
10.1038/nature08750 · ExternalCitation · doi-reference
BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis
10.1038/nature12199 · ExternalCitation · doi-reference
Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development
10.1038/nature12910 · ExternalCitation · doi-reference
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
10.1038/nature20810 · ExternalCitation · doi-reference
Stability and function of regulatory T cells expressing the transcription factor T-bet
10.1038/nature22360 · ExternalCitation · doi-reference
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
10.1038/ni.1774 · ExternalCitation · doi-reference
Continuous requirement for the TCR in regulatory T cell function
10.1038/ni.3004 · ExternalCitation · doi-reference
Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection
10.1038/ni.3837 · ExternalCitation · doi-reference
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
10.1038/ni1160 · ExternalCitation · doi-reference
T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alpha
10.1038/ni1394 · ExternalCitation · doi-reference
Disruption of diacylglycerol metabolism impairs the induction of T cell anergy
10.1038/ni1400 · ExternalCitation · doi-reference
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
10.1038/ni904 · ExternalCitation · doi-reference
Enhanced T cell responses due to diacylglycerol kinase zeta deficiency
10.1038/ni958 · ExternalCitation · doi-reference
Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
10.1038/nm.2426 · ExternalCitation · doi-reference
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis
10.1038/nm.3432 · ExternalCitation · doi-reference
T cell receptor signalling in the control of regulatory T cell differentiation and function
10.1038/nri.2016.26 · ExternalCitation · doi-reference
The plasticity and stability of regulatory T cells
10.1038/nri3464 · ExternalCitation · doi-reference
A brief history of T cell help to B cells
10.1038/nri3803 · ExternalCitation · doi-reference
Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases
10.1038/s41423-020-00529-z · ExternalCitation · doi-reference
Essential and non-overlapping IL-2Rα-dependent processes for thymic development and peripheral homeostasis of regulatory T cells
10.1038/s41467-019-08960-1 · ExternalCitation · doi-reference
Diacylglycerol kinase control of protein kinase C
10.1042/bcj20180620 · ExternalCitation · doi-reference
Synergistic control of T cell development and tumor suppression by diacylglycerol kinase alpha and zeta
10.1073/pnas.0711856105 · ExternalCitation · doi-reference
Poly(ADP-ribosyl)ation of FOXP3 protein mediated by PARP-1 regulates the function of regulatory T cells
10.1074/jbc.a115.661611 · ExternalCitation · doi-reference
Foxp3 protein stability is regulated by cyclin-dependent kinase 2*
10.1074/jbc.m113.467704 · ExternalCitation · doi-reference
Pim-2 kinase influences regulatory T cell function and stability by mediating Foxp3 protein N-terminal phosphorylation
10.1074/jbc.m115.638221 · ExternalCitation · doi-reference
Mammalian Sterile 20-like Kinase 1 (Mst1) enhances the stability of forkhead box P3 (Foxp3) and the function of regulatory T cells by modulating Foxp3 Acetylation
10.1074/jbc.m115.668442 · ExternalCitation · doi-reference
Tumor progression Locus 2 (Tpl2) activates the mammalian target of Rapamycin (mTOR) pathway, inhibits Forkhead Box P3 (FoxP3) expression, and limits regulatory T Cell (Treg) immunosuppressive functions
10.1074/jbc.m116.718783 · ExternalCitation · doi-reference
Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers
10.1084/jem.190.8.1115 · ExternalCitation · doi-reference
BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms
10.1084/jem.20141380 · ExternalCitation · doi-reference
Control of Foxp3 stability through modulation of TET activity
10.1084/jem.20151438 · ExternalCitation · doi-reference
B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity
10.1084/jem.20170580 · ExternalCitation · doi-reference
Deficiency in T follicular regulatory cells promotes autoimmunity
10.1084/jem.20170901 · ExternalCitation · doi-reference
FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program
10.1084/jem.20181134 · ExternalCitation · doi-reference
PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance
10.1084/jem.20182232 · ExternalCitation · doi-reference
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state
10.1093/intimm/10.12.1969 · ExternalCitation · doi-reference
Lineage stability and phenotypic plasticity of Foxp3(+) regulatory T cells
10.1111/imr.12175 · ExternalCitation · doi-reference
T follicular regulatory cells
10.1111/imr.12411 · ExternalCitation · doi-reference
Control of regulatory T cell development by the transcription factor Foxp3
10.1126/science.1079490 · ExternalCitation · doi-reference
Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer’s patches
10.1126/science.1169152 · ExternalCitation · doi-reference
CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner
10.1126/science.1172702 · ExternalCitation · doi-reference
Stability of the regulatory T cell lineage in vivo
10.1126/science.1191996 · ExternalCitation · doi-reference
Treg cells-the next frontier of cell therapy
10.1126/science.aau2688 · ExternalCitation · doi-reference
Identification of a T follicular helper cell subset that drives anaphylactic IgE
10.1126/science.aaw6433 · ExternalCitation · doi-reference
Expression of Foxp3 by T follicular helper cells in end-stage germinal centers
10.1126/science.abe5146 · ExternalCitation · doi-reference
T(fr) cells lack IL-2Ralpha but express decoy IL-1R2 and IL-1Ra and suppress the IL-1-dependent activation of T(fh) cells
10.1126/sciimmunol.aan0368 · ExternalCitation · doi-reference
Developmental bifurcation of human T follicular regulatory cells
10.1126/sciimmunol.abd8411 · ExternalCitation · doi-reference
Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells
10.1126/sciimmunol.adf6717 · ExternalCitation · doi-reference
The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling
10.1126/scisignal.2004373 · ExternalCitation · doi-reference
Diacylglycerol kinase ζ limits the generation of natural regulatory T cells
10.1126/scisignal.2004411 · ExternalCitation · doi-reference
Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1
10.1126/scitranslmed.aad1565 · ExternalCitation · doi-reference
Enhanced effector responses in activated CD8+ T cells deficient in diacylglycerol kinases
10.1158/0008-5472.can-12-3874 · ExternalCitation · doi-reference
CRISPR/Cas9-mediated knockout of DGK improves antitumor activities of human T cells
10.1158/0008-5472.can-18-0030 · ExternalCitation · doi-reference
PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21
10.1172/jci.insight.130062 · ExternalCitation · doi-reference
Negative regulation of mTOR activation by diacylglycerol kinases
10.1182/blood-2010-08-300731 · ExternalCitation · doi-reference
The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6
10.15252/embj.201591459 · ExternalCitation · doi-reference
Unexpected positive control of NFκB and miR-155 by DGKα and ζ ensures effector and memory CD8+ T cell differentiation
10.18632/oncotarget.8164 · ExternalCitation · doi-reference
Diacylglycerol kinases in T cell tolerance and effector function
10.3389/fcell.2016.00130 · ExternalCitation · doi-reference
DGK α and ζ activities control TH1 and TH17 cell differentiation
10.3389/fimmu.2019.03048 · ExternalCitation · doi-reference
Regulation of intrinsic and bystander T follicular helper cell differentiation and autoimmunity by Tsc1
10.3389/fimmu.2021.620437 · ExternalCitation · doi-reference
SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling
10.4049/jimmunol.1002476 · ExternalCitation · doi-reference
Tight regulation of diacylglycerol-mediated signaling is critical for proper invariant NKT cell development
10.4049/jimmunol.1100495 · ExternalCitation · doi-reference
Murine regulatory T cells contain hyperproliferative and death-prone subsets with differential ICOS expression
10.4049/jimmunol.1102448 · ExternalCitation · doi-reference
TCR signaling events are required for maintaining CD4 regulatory T cell numbers and suppressive capacities in the periphery
10.4049/jimmunol.1400477 · ExternalCitation · doi-reference
The lupus susceptibility gene Pbx1 regulates the balance between follicular helper T cell and regulatory T cell differentiation
10.4049/jimmunol.1502283 · ExternalCitation · doi-reference
B cells drive autoimmunity in mice with CD28-deficient regulatory T cells
10.4049/jimmunol.1700409 · ExternalCitation · doi-reference
A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells
10.4049/jimmunol.181.1.225 · ExternalCitation · doi-reference
BATF regulates T regulatory cell functional specification and fitness of triglyceride metabolism in restraining allergic responses
10.4049/jimmunol.2001184 · ExternalCitation · doi-reference
Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses
10.7554/elife.17936 · ExternalCitation · doi-reference
