Abstract
This study assessed the feasibility, effect on medication adherence, and safety of a novel fixed-dose heart failure with reduced ejection fraction polypill compared with usual care in Sri Lanka.
Anubha Agarwal, Asita de Silva, Mansi Agarwal, Saumiyah Ajanthan, Anuradha Dahanayaka, Rupasvi Dhurjati, Chanaka Fernando, Gamini Galappatthy, Charles W. Goss, Adam Hively, Pathiyil B. Jayagopal, Padinhare P. Mohanan, Anushka Patel, Mohamed Rahuman, Karl Roberts, Hyndavi Salwa, Abdul Salam
Abstract
Authors
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Global variations in heart failure etiology, management, and outcomes.
10.1001/jama.2023.5942 · 2023
Improving care for heart failure with reduced ejection fraction-a potential polypill-based strategy.
10.1001/jama.2020.21395 · 2020
Heart failure with reduced ejection fraction polypill implementation strategy in Sri Lanka: design and protocol of a pilot type I hybrid randomised clinical trial.
10.1136/bmjopen-2025-100952 · 2025
Delivering quadruple therapy for heart failure with reduced ejection fraction in a customizable polypill: the COMBO-HF-X pilot randomized trial.
10.1016/j.jchf.2026.103223
Polypill for heart failure with reduced ejection fraction: the POLY-HF randomized trial.
10.1038/s41591-026-04504-5 · 2026
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crossref
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pubmed
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datacite
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