Abstract
ABSTRACT
Introduction
Acute‐on‐chronic liver failure (ACLF) in pregnancy is a rare, life‐threatening condition with high maternal and fetal mortality.
Methods
We report a twin‐pregnant patient with ACLF managed by a multidisciplinary team. Interventions included comprehensive medical therapy, seven sessions of artificial liver support (plasma exchange), symptom control, nutritional and psychological care, and prophylactic measures against mother‐to‐child transmission.
Results
The patient successfully delivered healthy twins. Postdelivery, both infants tested negative for HBsAg and HBV‐DNA, confirming effective prevention of vertical transmission. Maternal condition stabilized with treatment.
Conclusion
Multidisciplinary management incorporating artificial liver therapy and tailored obstetric care can achieve favorable maternal and neonatal outcomes in ACLF during twin pregnancy.