Abstract
ABSTRACT
Aim
This nationwide observational study investigated recent trends in pancreatic cancer (PC) incidence and surgical management in Japan.
Methods
Annual data on PC incidence (2016–2021) and surgical procedures (2016–2023) were obtained from the Cancer Information Database and the National Database of Health Insurance Claims and Specific Health Checkups (NDB), respectively. Surgical procedures were categorized by type (distal pancreatectomy (DP, 2016–2023)/pancreatoduodenectomy (PD, 2020–2023)) and approach (open/laparoscopic). Crude and age‐adjusted rates per 100 000 person‐years were calculated. Temporal trends were evaluated using linear and Poisson regression to estimate annual risk ratios (RRs).
Results
Over the study period, the annual average PC incidence was 43 015, and the average number of PC surgery was 13 899. Age‐adjusted PC incidence rates rose significantly among males, females, and both sexes (RR = 1.007, 1.016 and 1.011, respectively;
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Conclusion
These nationwide findings highlight age‐ and sex‐specific signals—notably an apparent rise among young women and increased DP use among older adults—that warrant further validation.