Abstract
Abstract
Background:
The significance of osteitis in the management of recalcitrant chronic rhinosinusitis (CRS) has yet to be clearly understood and clinical outcomes data for these patients is lacking. Osteitis has been characterized by inflammatory infiltrate, osteoneogenesis, and bony sclerosis with remodeling. In this study we sought to determine if osteitis negatively impacts quality‐of‐life (QOL) or clinical outcomes following endoscopic sinus surgery (ESS).
Methods:
A total of 190 adult patients with CRS were prospectively enrolled. Osteitis was characterized by quantifiable bony thickening on sinus computed tomography (CT). Baseline measures and postoperative outcomes were evaluated using endoscopy exam, olfactory testing, and 2 validated disease‐specific QOL surveys: the Chronic Sinusitis Survey (CSS) and Rhinosinusitis Disability Index (RSDI). Bivariate and multivariate analyses were performed to evaluate differences between patients with and without osteitis.
Results:
Patients with osteitis (n = 79) had higher prevalence of nasal polyposis and prior ESS (both p p p = 0.011).
Conclusion:
Osteitis is associated with worse baseline measures of disease severity and inflammation. Our data suggest that whereas patients with osteitis improve after ESS, the presence of osteitis is associated with a reduced chance of improvement in some outcome measures. © 2011 ARS‐AAOA, LLC.