Abstract
ABSTRACT
Background and Purpose
The C‐reactive protein–triglyceride–glucose index (CTI), capturing insulin resistance (IR) and systemic inflammation, is related to stroke prognosis in general, but has not yet been studied with respect to functional outcomes after endovascular thrombectomy (EVT).
Methods
A retrospective analysis was carried out on individuals with acute ischemic stroke (AIS) experiencing EVT (September 2018–December 2024). CTI is measured as: 0.412 × Ln (C‐reactive protein) (mg/L) + Ln [fasting triglyceride (mg/dL) × fasting glucose (mg/dL)]/2. The endpoint was unfavorable functional outcomes, characterized by a modified Rankin Scale (mRS) score of 3–6 at 90‐day follow‐up. Restricted cubic splines (RCS) and logistic regression (LR) analysis were utilized to estimate the link between the CTI and clinical outcomes.
Results
Among 813 patients, a high CTI level was significantly correlated with unfavorable functional outcome (
p
Conclusion
The CTI is an independent indicator of functional outcomes in individuals with AIS undergoing EVT, underlining its potential clinical value as a readily accessible marker for risk stratification and individualized prognostic assessment.