Abstract
ABSTRACT
Objectives
With an aging society, the proportion of elderly patients undergoing gastric endoscopic submucosal dissection (ESD) is increasing. Although procedure‐related adverse events (AEs) are comparable between the elderly and non‐elderly patients, data on non‐procedure‐related AEs remain limited. This study aimed to evaluate the short‐ and long‐term outcomes of gastric ESD in elderly patients, focusing on risk factors for non‐procedure‐related AEs.
Methods
We retrospectively analyzed 941 patients who underwent gastric ESD at two institutions between 2011 and 2024. Patients were stratified into elderly (≥80 years) and non‐elderly (
Results
Procedure‐related AE rates were similar between the groups (8.9% vs. 7.1%,
p
= 0.322), whereas the overall (13.8% vs. 8.3%,
p
= 0.010) and non‐procedure‐related AE rates (5.8% vs. 1.4%,
p
p
= 0.013). Multivariate analysis identified systemic factors, including age, albumin level, CCI, and PS, as independent prognostic factors for OS in elderly patients.
Conclusions
Assessment of systemic health status, particularly using PS and CCI, is essential for predicting non‐procedure‐related AEs, and they are useful indices for determining treatment indications in elderly patients undergoing gastric ESD.
Trial Registration
: Not applicable.