Hedgehog signalling in colon cancer and stem cells

Elisabetta Ferretti; Enrico De Smaele

doi:10.1002/emmm.200900042

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Hedgehog signalling in colon cancer and stem cells

Elisabetta Ferretti, Enrico De Smaele

EMBO Molecular Medicine2009doi:10.1002/emmm.200900042

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Abstract

The participation of the HH pathway in colon cancer has remained controversial. In this issue, Varnat et al (2009) demonstrate that HH signalling is essential for human colon cancer growth, recurrence, metastases and stem cell expansion. This closeup by Gulino et al discusses the paper and its implications.

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Elisabetta Ferretti#2 Enrico De Smaele#3

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Cancerous stem cells: deviant stem cells with cancer-causing misbehavior

2010 · 0 citations

External reference records

10.1038/nrc2392

10.1038/nrc2392 · 2008

10.1136/gut.2007.127837

10.1136/gut.2007.127837 · 2008

10.1158/0008-5472.can-09-0756

10.1158/0008-5472.can-09-0756 · 2009

10.1002/10.1002/emmm.200900039

10.1101/gad.1693608

10.1101/gad.1693608 · 2008

10.1038/nrc2499

10.1038/nrc2499 · 2008

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