Abstract
ABSTRACT
In support of a discovery biology project, a C‐14 labeled heme was required. The C‐14 label was located in the carbon connecting the A and B ring with a propionic acid side chain on both the C and D ring and alkyl substitution on the remaining positions of the pyrrole rings of the heme. The synthesis was achieved in 7 radiochemical steps and 11% radiochemical yield from
14
C‐formaldehyde. A stability study showed that the compound decayed at about 0.5%/month in a linear fashion.