Abstract
Asif Jan, Bushra Waheed, Rani Akbar, Daniel Dubwa
Abstract
Authors
Institutions
No local reference links have been materialized yet.
No local citing links have been materialized yet.
Precision medicine—personalized, problematic, and promising
10.1097/01.ogx.0000472121.21647.38 · 2015
Precision oncology: an overview
10.1200/jco.2013.49.4799 · 2013
The evolving landscape of tissue‐agnostic therapies in precision oncology
2024
Developing drugs for tissue‐agnostic indications: a paradigm shift in leveraging cancer biology for precision medicine
10.1002/cpt.1946 · 2021
Advances in tissue‐agnostic targeting in cancer therapeutics: current approvals, challenges, and future directions
10.32604/or.2025.067791 · 2025
The hallmarks of tissue‐agnostic therapies and strategies for early anticancer drug discovery
10.1016/j.drudis.2024.104203 · 2024
Tissue‐agnostic cancer therapy approvals
10.1016/j.soc.2023.12.001 · 2024
From tissue‐agnostic to N‐of‐one therapies:(R) evolution of the precision paradigm
10.1016/j.trecan.2020.08.009 · 2021
Rethinking cancer drug development through tumor‐agnostic precision medicine
10.1158/2159-8290.cd-25-1457 · 2025
Clinical implications of intratumor heterogeneity: challenges and opportunities
Provenance
crossref
Confidence 100%
ror
Confidence 99%
ror
Confidence 99%
ror
Confidence 99%
ror
Confidence 99%
openalex
Confidence 95%
datacite
Confidence 0%
10.1007/s00109-020-01874-2 · 2020
Tumor heterogeneity: development, mechanisms, and therapeutic implications
10.1038/s41392-026-02749-7 · 2026
Intratumoral heterogeneity, its contribution to therapy resistance and methodological caveats to assessment
10.3389/fonc.2014.00142 · 2014
Heterogeneity in precision oncology
10.1017/pcm.2023.23 · 2024
Cancer cell cycle heterogeneity as a critical determinant of therapeutic resistance
10.1016/j.gendis.2022.11.025 · 2024
Comprehensive multi‐omics analysis provides biological insights and therapeutic strategies for small‐cell lung cancer
10.1002/mco2.569 · 2024
Integrative multi‐omics approaches in cancer research: from biological networks to clinical subtypes
10.14348/molcells.2021.0042 · 2021
Liquid biopsy and multi‐omic biomarkers in breast cancer: innovations in early detection, therapy guidance, and disease monitoring
2025
Multi‐omics analysis: paving the path toward achieving precision medicine in cancer treatment and immuno‐oncology
10.3389/fmolb.2022.962743 · 2022
Unresolved referenced work
2025
Unresolved referenced work
Kept as external metadata until matched
Progress in research on tumor microenvironment‐based spatial omics technologies
10.32604/or.2023.029494 · 2023
Artificial intelligence meets epigenetics: a new frontier in precision oncology
10.1080/28361512.2026.2614541 · 2026
Genomics and the history of precision oncology
10.1016/j.soc.2019.08.003 · 2019
Advances in precision oncology: from molecular profiling to regulatory‐approved targeted therapies
10.3390/cancers17213500 · 2025
Integrated and comprehensive diagnostics: an emerging paradigm in precision oncology
10.3390/cancers18020327 · 2026
New clinical trial designs in the era of precision medicine: an overview of definitions, strengths, weaknesses, and current use in oncology
10.1016/j.ctrv.2018.12.003 · 2019
Deep learning: new computational modelling techniques for genomics
10.1038/s41576-019-0122-6 · 2019
Advancing precision oncology with AI‐powered genomic analysis
10.3389/fphar.2025.1591696 · 2025
Artificial intelligence in cancer research, diagnosis and therapy
10.1038/s41568-021-00399-1 · 2021
Artificial intelligence in variant calling: a review
10.3389/fbinf.2025.1574359 · 2025
Deep learning‐based prediction of tumor mutational burden from digital pathology slides: a comprehensive review
10.3390/app16031340 · 2026
Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer
10.1038/s41591-019-0462-y · 2019
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures
10.1038/nm.4292 · 2017
Explainable AI model reveals informative mutational signatures for cancer‐type classification
10.3390/cancers17111731 · 2025
Disease variant prediction with deep generative models of evolutionary data
10.1038/s41586-021-04043-8 · 2021
Tumor‐agnostic therapies in practice: challenges, innovations, and future perspectives
10.3390/cancers17050801 · 2025
Harnessing tumor‐agnostic biomarkers for precision medicine in lymphoma
2026
Antibody‐drug conjugates in precision oncology
10.1016/j.ccell.2026.05.004 · 2026
Antibody‐drug conjugates in solid tumor oncology and the frontier of precision immunosuppression: a mechanistic, translational, and clinical review
10.3390/ijms27125196 · 2026
Antibody–drug conjugates in cancer therapy: current landscape, challenges, and future directions
10.1186/s12943-025-02489-2 · 2025
Addressing the challenges of applying precision oncology
10.1038/s41698-017-0032-z · doi-reference
Challenges and solutions to system‐wide use of precision oncology as the standard of care paradigm
10.1017/pcm.2024.1 · doi-reference
Artificial intelligence in multidisciplinary tumor boards enhancing decision making and clinical outcomes in oncology
10.1016/j.isci.2025.114082 · doi-reference
AI‐driven multi‐omics integration in precision oncology: bridging the data deluge to clinical decisions
10.1007/s10238-025-01965-9 · doi-reference
PTOLEMI: personalized cancer treatment through machine learning‐enabled image analysis of microfluidic assays
10.3390/diagnostics13193075 · doi-reference
Applications of organoids for cancer biology and precision medicine
10.1038/s43018-020-0102-y · doi-reference
Liquid biopsy approaches for cancer characterization, residual disease detection, and therapy monitoring
10.1200/edbk-25-481114 · doi-reference
Liquid biopsy to detect minimal residual disease: methodology and impact
10.3390/cancers13215364 · doi-reference
Integrating cfDNA liquid biopsy and organoid‐based drug screening reveals PI3K signaling as a promising therapeutic target in colorectal cancer
10.1186/s12967-023-04675-6 · doi-reference
Liquid biopsy in cancer drug resistance: real‐time monitoring, mechanistic insights, and translational applications
10.3389/fimmu.2026.1795789 · doi-reference
Personalized cancer vaccines: bridging immune‐oncology and precision medicine for advanced therapeutics
10.1038/s41392-026-02769-3 · doi-reference
Recent advances in mRNA cancer vaccines: meeting challenges and embracing opportunities
10.3389/fimmu.2023.1246682 · doi-reference
Antibody drug conjugates in breast cancer: spotlight on HER2
10.1097/ppo.0000000000000634 · doi-reference
Bystander effect in antibody‐drug conjugates: navigating the fine line in tumor heterogeneity
10.1016/j.critrevonc.2025.104979 · doi-reference
The evolving landscape of antibody–drug conjugates: in depth analysis of recent research progress
10.1021/acs.bioconjchem.3c00374 · doi-reference
Clinical evidence for efficacy of pembrolizumab in MSI‐H and TMB‐H advanced solid tumor: results from three cancer centers in China
10.1007/s00262-024-03660-2 · doi-reference
Tumor type agnostic therapy carrying BRAF mutation: case reports and review of literature
10.3390/ph14020159 · doi-reference
Sacituzumab govitecan and trastuzumab deruxtecan: two new antibody–drug conjugates in the breast cancer treatment landscape
10.1016/j.esmoop.2021.100204 · doi-reference
Trop2‐targeted therapies in solid tumors: advances and future directions
10.7150/thno.98178 · doi-reference
Tissue‐agnostic cancer therapies: promise, reality, and the path forward
10.1038/s41467-025-60369-1 · doi-reference
Oncogenic driver mutations, treatment, and EGFR‐TKI resistance in a Caucasian population with non‐small cell lung cancer: survival in clinical practice
10.18632/oncotarget.20857 · doi-reference
Patient‐derived tumor organoids: a new avenue for preclinical research and precision medicine in oncology
10.1038/s12276-024-01272-5 · doi-reference
A review of circulating tumor DNA (ctDNA) and the liquid biopsy in cancer diagnosis, screening, and monitoring treatment response
10.12659/msm.949300 · doi-reference
The good, the bad, and the ugly: opportunities, challenges, and pitfalls in spatial proteomics modeling
10.1093/bib/bbag169 · doi-reference
Spatial transcriptomics, proteomics, and epigenomics as tools in tissue engineering and regenerative medicine
10.3390/bioengineering11121235 · doi-reference
Single‐cell multiomics
10.1146/annurev-biodatasci-020422-050645 · doi-reference
Significance and limitations of the use of next‐generation sequencing technologies for detecting mutational signatures
10.1016/j.dnarep.2021.103200 · doi-reference
Cancer‐associated fibroblasts in the tumor microenvironment: heterogeneity, crosstalk mechanisms, and therapeutic implications
10.1186/s12943-025-02533-1 · doi-reference
Spatial omics in clinical research: a comprehensive review of technologies and guidelines for applications
10.3390/ijms26093949 · doi-reference
From morphology to single‐cell molecules: high‐resolution 3D histology in biomedicine
10.1186/s12943-025-02240-x · doi-reference
Microfluidic single‐cell transcriptomics: moving towards multimodal and spatiotemporal omics
10.1039/d1lc00607j · doi-reference
The technological landscape and applications of single‐cell multi‐omics
10.1038/s41580-023-00615-w · doi-reference
Advances in microfluidic systems and numerical modeling in biomedical applications: a review
10.3390/mi15070873 · doi-reference
Quantitative analysis of IGF1R/AKT/mTOR pathway using multiplex immunoprecipitation and targeted mass spectrometry
10.1158/1538-7445.am2016-3884 · doi-reference
PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
10.1186/s12943-023-01827-6 · doi-reference
Proteomic analysis of protein posttranslational modifications by mass spectrometry
10.1101/pdb.top077743 · doi-reference
RNA‐Seq: a revolutionary tool for transcriptomics
10.1038/nrg2484 · doi-reference
Advances in epigenomic sequencing and their applications in cancer diagnostics
10.1021/prechem.5c00014 · doi-reference
The homologous recombination deficiency scar in advanced cancer: agnostic targeting of damaged DNA repair
10.3390/cancers14122950 · doi-reference
Microsatellite instability: a review of molecular epidemiology and implications for immune checkpoint inhibitor therapy
10.3390/cancers15082288 · doi-reference