Effect of granaticin on the activity of DNA-directed RNA polymerase fromStreptomyces granaticolor

J. Šmardová; J. Šťastná; M. Klégr

doi:10.1007/bf02814465

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Effect of granaticin on the activity of DNA-directed RNA polymerase fromStreptomyces granaticolor

J. Šmardová, J. Šťastná, M. Klégr

Folia Microbiologica1989doi:10.1007/bf02814465

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Abstract

DNA-directed RNA polymerase was isolated from wild-type and mutant (asporogenic and granaticin overproducing) Streptomyces granaticolor. The effect of granaticin on the enzyme activity was compared with that of standard transcription inhibitors, rifampicin and rifamycin SV and shown to be zero.

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J. Šmardová#1 J. Šťastná#3 M. Klégr#4

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