Structural bioinformatics in personalized medicine

Variant calling: considerations, practices, and developments

10.1002/humu.24311 · doi-reference

Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials

10.1038/s41587-023-01934-1 · doi-reference

Genetic heterogeneity: challenges, impacts, and methods through an associative lens

10.1002/gepi.22497 · doi-reference

Undiagnosed rare genetic disorders: importance of functional characterization of variants

10.3390/genes14071469 · doi-reference

Wearable biomolecular sensing nanotechnologies in chronic disease management

10.1038/s41565-025-02010-2 · doi-reference

Combining structure and genomics to understand antimicrobial resistance

10.1016/j.csbj.2020.10.017 · doi-reference

AI-driven advancements in bioinformatics: transforming healthcare and science

10.4103/jpbs.jpbs_389_25 · doi-reference

Use of AI-methods over MD simulations in the sampling of conformational ensembles in IDPs

10.3389/fmolb.2025.1542267 · doi-reference

Advances of reverse vaccinology for mRNA vaccine design against SARS-CoV-2: a review of methods and tools

10.3390/v15102130 · doi-reference

Integrating multi-omics data: methods and applications in human complex diseases

10.1016/j.btre.2025.e00938 · doi-reference

Third-generation sequencing of epigenetic DNA

10.1002/anie.202215704 · doi-reference

Pharmacogenomics: driving personalized medicine

10.1124/pharmrev.122.000810 · doi-reference

Structure-based classification predicts drug response in EGFR-mutant NSCLC

10.1038/s41586-021-03898-1 · doi-reference

Advances in AI for protein structure prediction: implications for cancer drug discovery and development

10.3390/biom14030339 · doi-reference

Recent advances and challenges in protein structure prediction

10.1021/acs.jcim.3c01324 · doi-reference

MultiOmicsIntegrator: a nextflow pipeline for integrated omics analyses

10.1093/bioadv/vbae175 · doi-reference

Prediction of impacts of mutations on protein structure and interactions: SDM, a statistical approach, and mCSM, using machine learning

10.1002/pro.3774 · doi-reference

Structural variants: mechanisms, mapping, and interpretation in human genetics

10.3390/genes16080905 · doi-reference

Data structuring of electronic health records: a systematic review

10.1007/s12553-021-00607-w · doi-reference

Bioinformatics and artificial intelligence in genomic data analysis: current advances and future directions

10.1007/s00438-025-02314-x · doi-reference

Structural bioinformatics for rational drug design

10.1016/j.rpth.2025.102691 · doi-reference

Revolutionizing personalized medicine: synergy with multi-omics data generation, main hurdles, and future perspectives

10.3390/biomedicines12122750 · doi-reference

Comparative analysis of machine learning models for predicting innovation outcomes: an applied AI approach

10.3390/app15073636 · doi-reference

Personalized cancer vaccines: current advances and emerging horizons

10.3390/vaccines13121231 · doi-reference

AI accelerate the identification of druggable targets by 3D structures of proteins and compounds

10.1038/s41698-026-01310-7 · doi-reference

Deep learning for protein structure prediction and design—progress and applications

10.1038/s44320-024-00016-x · doi-reference

Highly accurate protein structure prediction with AlphaFold

10.1038/s41586-021-03819-2 · doi-reference

High-throughput single-сell sequencing in cancer research

10.1038/s41392-022-00990-4 · doi-reference

10.1007/978-3-031-87873-2_20

10.1007/978-3-031-87873-2_20 · doi-reference

Unraveling the structural and functional consequences of non-synonymous single-nucleotide polymorphisms (nsSNPs) in human SOCS2: an in silico approach

10.1186/s43042-025-00669-9 · doi-reference

10.1007/978-3-030-96308-8_98

10.1007/978-3-030-96308-8_98 · doi-reference

Precision medicine and the problem of structural injustice

10.1007/s11019-023-10158-8 · doi-reference

CRISPR technology in disease management: an updated review of clinical translation and therapeutic potential

10.1111/cpr.70099 · doi-reference

Integration of multi-omics approaches in exploring intra-tumoral heterogeneity

10.1186/s12935-025-03944-2 · doi-reference

Precision and personalized medicine: what their current definition says and silences about the model of health they promote. Implication for the development of personalized health

10.3389/fsoc.2023.1112159 · doi-reference

Protein structure-based evaluation of missense variants: resources, challenges and future directions

10.1016/j.sbi.2023.102600 · doi-reference

Recent advances in cellular and molecular bioengineering for building and translation of biological systems

10.1007/s12195-021-00676-x · doi-reference

Tripathi, Comparative analysis of web-based programs for single amino acid substitutions in proteins

10.1371/journal.pone.0267084 · doi-reference

Proteins with alternative folds reveal blind spots in AlphaFold-based protein structure prediction

10.1016/j.sbi.2024.102973 · doi-reference

Clinical cancer genomic profiling

10.1038/s41576-021-00338-8 · doi-reference