Abstract
Rights: ALLOWED · cc-by · Source: journal-auto-sync:external:CROSSREF_ISSN
Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Merlin Friedemann, Eneken Helk, Ann Tiiman, Kairit Zovo, Peep Palumaa, Vello Tõugu
Open the manuscript using the link above. DOC files open in Word or a compatible document reader.
Abstract
Rights: ALLOWED · cc-by · Source: journal-auto-sync:external:CROSSREF_ISSN
Open the manuscript using the link above. DOC files open in Word or a compatible document reader.
Authors
Institutions
No ROR-resolved institution is linked to this work yet.
Provenance
crossref
Confidence 100%
pubmed
Confidence 98%
europepmc
Confidence 96%
unpaywall
Confidence 95%
datacite
Confidence 0%
No local reference links have been materialized yet.
No local citing links have been materialized yet.
Open the manuscript using the link above. DOC files open in Word or a compatible document reader.
Oxidative damage is the earliest event in Alzheimer disease
10.1093/jnen/60.8.759 · 2001
Abeta, oxidative stress in Alzheimer disease: evidence based on proteomics studies
10.1016/j.bbadis.2013.09.015 · 2014
Review: Alzheimer’s amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity
10.1006/jsbi.2000.4274 · 2000
Amyloid-β production: major link between oxidative stress and BACE1
10.1007/s12640-011-9283-6 · 2012
Methionine-35 of Abeta(1-42): importance for oxidative stress in alzheimer disease
10.4061/2011/198430 · 2011
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease
10.1073/pnas.91.8.3270 · 1994
Methionine residue 35 is critical for the oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide 1-42
10.1016/s0196-9781(02)00066-9 · 2002
Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging
10.1073/pnas.91.18.8378 · 1994
Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains
10.1074/jbc.m007859200 · 2001
The redox chemistry of the Alzheimer's disease amyloid beta peptide
1768
Solution structure of methionine-oxidized amyloid beta-peptide (1-40). Does oxidation affect conformational switching?
10.1021/bi9810757 · 1998
Methionine 35 oxidation reduces fibril assembly of the amyloid abeta-(1-42) peptide of Alzheimer's disease
10.1074/jbc.c200338200 · 2002
Effects of different amyloid beta-protein analogues on synaptic function
10.1016/j.neurobiolaging.2012.06.027 · 2013
Oxidation of methionine 35 reduces toxicity of the amyloid beta-peptide(1-42) in neuroblastoma cells (IMR-32) via enzyme methionine sulfoxide reductase A expression and function
10.1016/j.neuint.2010.01.002 · 2010
Alzheimer’s amyloid beta-peptide (1-42) induces cell death in human neuroblastoma via bax/bcl-2 ratio increase: an intriguing role for methionine 35
10.1016/j.bbrc.2006.01.137 · 2006
Enhanced toxicity and cellular binding of a modified amyloid beta peptide with a methionine to valine substitution
10.1074/jbc.m406465200 · 2004
Despite its role in assembly, methionine 35 is not necessary for amyloid beta-protein toxicity
10.1111/j.1471-4159.2010.06692.x · 2010
Free radical reactions of methionine in peptides: mechanisms relevant to beta-amyloid oxidation and Alzheimer's disease
10.1021/ja036733b · 2003
Bioinorganic chemistry of Alzheimer’s disease
10.1021/cr300009x · 2012
Interactions of Zn(II) and Cu(II) ions with Alzheimer's amyloid-beta peptide. Metal ion binding, contribution to fibrillization and toxicity
10.1039/c0mt00073f · 2011
In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis
10.1074/jbc.m210207200 · 2003
Label-free high-throughput screening assay for inhibitors of Alzheimer's amyloid-beta peptide aggregation based on MALDI MS
10.1021/ac101583q · 2010
Improved electrophoretic separation and immunoblotting of beta-amyloid (A beta) peptides 1-40, 1-42, and 1-43
10.1002/elps.1150180332 · 1997
Detection of Proteins in Polyacrylamide Gels by Silver Staining
2002
Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-beta (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators
10.1111/j.1471-4159.2009.06269.x · 2009
Effect of agitation on the peptide fibrillization: Alzheimer’s amyloid-beta peptide 1-42 but not amylin and insulin fibrils can grow under quiescent conditions
10.1002/psc.2513 · 2013
The catalytically active copper-amyloid-beta state: coordination site responsible for reactive oxygen species production
10.1002/anie.201305372 · 2013
Abeta(31-35) and Abeta(25-35) fragments of amyloid beta-protein induce cellular death through apoptotic signals: role of the redox state of methionine-35
10.1016/j.febslet.2005.04.041 · 2005
Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1-42) and A beta(25-35)
10.1021/ja010452r · 2001
In vitro peroxidase oxidation induces stable dimers of beta-amyloid (1-42) through dityrosine bridge formation
10.3109/13506129908993282 · 1999
Oligomers, fact or artefact? SDS-PAGE induces dimerization of beta-amyloid in human brain samples
10.1007/s00401-013-1083-z · 2013
Methionine does not reduce Cu(II)-beta-amyloid! – rectification of the roles of methionine-35 and reducing agents in metal-centered oxidation chemistry of Cu(II)-beta-amyloid
10.1016/j.bbadis.2008.11.004 · 2009
The protein oxidation repair enzyme methionine sulfoxide reductase a modulates abeta aggregation and toxicity in vivo
10.1089/ars.2013.5803 · 2014
Intracellular accumulation of amyloid-beta (Abeta) protein plays a major role in Abeta-induced alterations of glutamatergic synaptic transmission and plasticity
10.1523/jneurosci.1201-14.2014 · 2014
No additional external references are available.