Abstract
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Junyu Xiang, Shuoran Tian, Xiangming Wang, Zhaole Chu, Zailiang Yang, Weiwu Gao, Biying Liu, Zengjie Lei, Xiaochun Shen, Yinbin Zhou, Linghong Wan, Quanyou Zheng, Wenkang Liu, Jinyang Li, Linyu Wu, Yongying Hou, Xipeng Zheng, Huilin Pan, Shixin Qin, Mengting Sun, Fanxuan Tian, Ziyi Peng, Zhaoyang Zhong, Chuan Chen, Shunan Wang, Dongfeng Chen, Liangzhi Wen, Qiaoqiao Zhang, Cheng Lin, Zhongyi Qin, Zhifeng Miao, Xiu-Wu Bian, Zhenning Wang, Fan Bai
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Cutadapt removes adapter sequences from high-throughput sequencing reads
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10.6026/97320630002005 · doi-reference
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SortMeRNA: fast and accurate filtering of ribosomal RNAs in metatranscriptomic data
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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
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TFBSTools: an R/bioconductor package for transcription factor binding site analysis
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MAnorm2 for quantitatively comparing groups of ChIP-seq samples
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10.1093/bioinformatics/btq033 · doi-reference
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10.1186/gb-2008-9-9-r137 · doi-reference
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