Mitochondrial dysfunction in environmental toxicology: mechanisms, impacts, and health implications
10.1021/acs.chemrestox.4c00328 · doi-reference
Alterations of gut microbiota and its metabolomics in children with 6PPDQ, PBDE, PCB, and metal (loid) exposure
10.1016/j.jhazmat.2024.134862 · doi-reference
A nation-wide study for the occurrence of PPD antioxidants and 6PPD-quinone in road dusts of China
10.1016/j.scitotenv.2024.171393 · doi-reference
Widespread N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone in size-fractioned atmospheric particles and dust of different indoor environments
10.1021/acs.estlett.2c00193 · doi-reference
EGFR and CYP signaling disruption underlies 6PPD-quinone hepatotoxicity: Insights from a network and machine learning approach
10.1016/j.tox.2025.154235 · doi-reference
Widespread occurrence and transport of p-phenylenediamines and their quinones in sediments across urban rivers, estuaries, coasts, and deep-sea regions
10.1021/acs.est.2c07652 · doi-reference
Toxicity of ubiquitous tire rubber antiozonant N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its transformation product 6PPD-quinone (6PPD-Q) in primary human hepatocytes and liver spheroids
10.1016/j.bbrep.2025.102199 · doi-reference
Environmentally realistic dose of tire-derived metabolite 6PPD-Q exposure causes intestinal jejunum and ileum damage in mice via cannabinoid receptor-activated inflammation
10.1016/j.scitotenv.2024.170679 · doi-reference
From exposure models to multi-organ toxicity of 6PPD-quinone in mice: A mini-review
10.1016/j.ecoenv.2026.119812 · doi-reference
Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264. 7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK
10.1016/j.jhazmat.2020.122549 · doi-reference
Macrophage biology in development, homeostasis and disease
10.1038/nature12034 · doi-reference
6-PPD quinone at environmentally relevant concentrations induces immunosenescenece by causing immunosuppression during the aging process
10.1016/j.chemosphere.2024.143719 · doi-reference
A new toxicity mechanism of N-(1, 3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone: Formation of DNA adducts in mammalian cells and aqueous organisms
10.1016/j.scitotenv.2022.161373 · doi-reference
First evidence of the bioaccumulation and trophic transfer of tire additives and their transformation products in an estuarine food web
10.1021/acs.est.3c10248 · doi-reference
Transgenerational intestinal toxicity of 6-PPD quinone in causing ROS production, enhancement in intestinal permeability and suppression in innate immunity in C. elegans
10.1016/j.envpol.2024.125208 · doi-reference
Beyond substituted p-Phenylenediamine antioxidants: Prevalence of their quinone derivatives in PM2. 5
10.1021/acs.est.2c02463 · doi-reference
6PPD and 6PPDQ exposure promote the proliferation and migration of non-small cell lung cancer cells through PTEN dysfunction and ARG2-mediated metabolic reprogramming
10.1016/j.jhazmat.2025.139088 · doi-reference
Membrane lipids: where they are and how they behave
10.1038/nrm2330 · doi-reference
Update and nomenclature proposal for mammalian lysophospholipid acyltransferases, which create membrane phospholipid diversity
10.1016/j.jbc.2021.101470 · doi-reference
Biosynthetic enzymes of membrane glycerophospholipid diversity as therapeutic targets for drug development
10.1007/978-3-030-50621-6_2 · doi-reference
A ubiquitous tire rubber–derived chemical induces acute mortality in coho salmon
10.1126/science.abd6951 · doi-reference
Immunometabolism-modulation and immunotoxicity evaluation of perfluorooctanoic acid in macrophage
10.1016/j.ecoenv.2021.112128 · doi-reference
N-acetylcysteine (NAC): impacts on human health
10.3390/antiox10060967 · doi-reference
Zinc oxide nanoparticles cause hepatotoxicity in rare minnow (Gobiocypris rarus) via ROS-mediated oxidative stress and apoptosis activation and inhibition of lipid peroxidation
10.1016/j.aqrep.2024.102317 · doi-reference
Oxidative stress: a concept in redox biology and medicine
10.1016/j.redox.2015.01.002 · doi-reference
Macrophage plasticity and polarization: in vivo veritas
10.1172/jci59643 · doi-reference
Environmental occurrence, fate, human exposure, and human health risks of p-phenylenediamines and their quinones
10.1016/j.scitotenv.2024.177742 · doi-reference
Unveiling a macrophage-driven inflammatory dysregulation: NF-κB-mediated hyperinflammation links 6PPD-Q exposure to viral immunopathology
10.1016/j.jhazmat.2026.141632 · doi-reference
Correlation between 6PPD-Q and immune along with metabolic dysregulation induced liver lesions in outdoor workers
10.1016/j.envint.2025.109455 · doi-reference
Protective and pathogenic functions of macrophage subsets
10.1038/nri3073 · doi-reference
Macrophage activation and polarization: nomenclature and experimental guidelines
10.1016/j.immuni.2014.06.008 · doi-reference
Crosstalk of reactive oxygen species and NF-κB signaling
10.1038/cr.2010.178 · doi-reference
Lysophosphatidic Acid, a Multifunctional Phospholipid Messenger
10.1074/jbc.270.22.12949 · doi-reference
Comparative acute and combinative toxicity of aflatoxin B1 and T‐2 toxin in animals and immortalized human cell lines
10.1002/jat.1117 · doi-reference
Exposure to the tire rubber-derived contaminant 6PPD-Quinone causes mitochondrial dysfunction in vitro
10.1021/acs.estlett.2c00431 · doi-reference
Alterations of IL-1beta and TNF-alpha expression in RAW264. 7 cell damage induced by two samples of PM2. 5 with different compositions
10.1177/00368504221113709 · doi-reference
