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FDA approvals of oncology drugs for tissue-agnostic indications
10.1007/s11523-023-00982-6 · 2023
Tumor-Agnostic Precision Medicine from the AACR GENIE Database: Clinical Implications
10.1158/1078-0432.ccr-23-0090 · 2023
Unresolved referenced work
Kept as external metadata until matched
Unresolved referenced work
2022
Unresolved referenced work
2022
Unresolved referenced work
2022
Unresolved referenced work
2022
Unresolved referenced work
2022
Unresolved referenced work
2022
Precision Oncology for BRAF Mutant Cancers with BRAF and MEK inhibitors: From Melanoma to Tissue-agnostic therapy
10.1016/j.esmoop.2023.100788 · 2023
The role of BRAF V600 mutation in melanoma
10.1186/1479-5876-10-85 · 2012
Mutations of the BRAF gene in human cancer
10.1038/nature00766 · 2002
Diagnostic accuracy of immunohistochemistry compared with molecular tests for detection of BRAF V600E mutation in ameloblastomas: Systematic review and meta-analysis
10.1111/jop.13278 · 2022
The Current State of Molecular Testing in the BRAF-Mutated Melanoma Landscape
10.3389/fmolb.2020.00113 · 2020
Comparison of diagnostic methods for the detection of a BRAF mutation in papillary thyroid cancer
2019
Expanding the Benefit: Dabrafenib/Trametinib as Tissue-Agnostic Therapy for BRAF V600E-Positive Adult and Pediatric Solid Tumors
10.1200/edbk_404770 · 2023
Dabrafenib and Trametinib in Patients With Tumors With BRAF(V600E) Mutations: Results of the NCI-MATCH Trial Subprotocol H
10.1200/jco.20.00762 · 2020
Dabrafenib plus trametinib combination therapy in pediatric patients with BRAF V600-mutant low-grade glioma: Safety and efficacy results
2020
Unresolved referenced work
Kept as external metadata until matched
Efficacy and safety of trametinib monotherapy or in combination with dabrafenib in pediatric BRAF V600-mutant low-grade glioma
2022
Combined PD-1, BRAF and MEK inhibition in BRAF(V600E) colorectal cancer: a phase 2 trial
10.1038/s41591-022-02181-8 · 2023
Unresolved referenced work
2022
The development of a potent, KDRNEGFR2-sparing RET kinase inhibitor for treating patients with RET-dependent cancers
10.1016/s0959-8049(16)33028-3 · 2016
Selective RET kinase inhibition for patients with RET-altered cancers
10.1093/annonc/mdy137 · 2018
Targeting RET-driven cancers: lessons from evolving preclinical and clinical landscapes
10.1038/nrclinonc.2017.175 · 2018
RET tyrosine kinase signaling in development and cancer
10.1016/j.cytogfr.2005.05.010 · 2005
The RET proto-oncogene in human cancers
10.1038/sj.onc.1203857 · 2000
Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC
10.1093/hmg/2.7.851 · 1993
A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma
10.1038/367375a0 · 1994
Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A
10.1038/363458a0 · 1993
ESMO recommendations on the standard methods to detect RET fusions and mutations in daily practice and clinical research
10.1016/j.annonc.2020.11.021 · 2021
Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies
10.1038/nm.2673 · 2012
RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer
10.1200/jco.2012.44.1477 · 2012
A retrospective analysis of RET translocation, gene copy number gain and expression in NSCLC patients treated with vandetanib in four randomized Phase III studies
10.1186/s12885-015-1146-8 · 2015
RET-rearranged non-small-cell lung carcinoma: a clinicopathological and molecular analysis
10.1038/bjc.2014.36 · 2014
Diagnostic method for the detection of KIF5B-RET transformation in lung adenocarcinoma
10.1016/j.lungcan.2013.07.009 · 2013
The International Epidemiology of Lung Cancer: Latest Trends, Disparities, and Tumor Characteristics
10.1016/j.jtho.2016.05.021 · 2016
Thyroid carcinoma: molecular pathways and therapeutic targets
10.1038/modpathol.2008.10 · 2008
Molecular mechanisms underlying oncogenic RET fusion in lung adenocarcinoma
10.1097/jto.0000000000000135 · 2014
Clinical and Translational Implications of RET Rearrangements in Non-Small Cell Lung Cancer
10.1016/j.jtho.2017.10.021 · 2018
The use of neoadjuvant larotrectinib in the management of children with locally advanced TRK fusion sarcomas
10.1002/cncr.31701 · doi-reference
Neoadjuvant selpercatinib for advanced medullary thyroid cancer
10.1002/hed.26527 · doi-reference
Neoadjuvant Selective RET Inhibitor for Medullary Thyroid Cancer: A Case Series
10.1089/thy.2022.0506 · doi-reference
Neoadjuvant Pembrolizumab in Localized Microsatellite Instability High/Deficient Mismatch Repair Solid Tumors
10.1200/jco.22.01351 · doi-reference
What are the advantages of neoadjuvant immunotherapy over adjuvant immunotherapy?
10.1080/14737140.2022.2069097 · doi-reference
Complete Surgical Resection Following Neoadjuvant Dabrafenib Plus Trametinib in BRAF(V600E)-Mutated Anaplastic Thyroid Carcinoma
10.1089/thy.2019.0133 · doi-reference
A Phase 2 Study of Pemigatinib (FIGHT-203; INCB054828) in Patients with Myeloid/Lymphoid Neoplasms (MLNs) with Fibroblast Growth Factor Receptor 1 (FGFR1) Rearrangement (MLN FGFR1)
10.1182/blood-2021-148103 · doi-reference
ALK fusions in the pan-cancer setting: another tumor-agnostic target?
10.1038/s41698-023-00449-x · doi-reference
First-in-human study of PC14586, a small molecule structural corrector of Y220C mutant p53, in patients with advanced solid tumors harboring a TP53 Y220C mutation
10.1200/jco.2022.40.16_suppl.3003 · doi-reference
Efficacy and safety of zenocutuzumab, a HER2 x HER3 bispecific antibody, across advanced NRG1 fusion (NRG1+) cancers
10.1200/jco.2022.40.16_suppl.105 · doi-reference
Efficacy and Safety of Trastuzumab Deruxtecan in Patients With HER2-Expressing Solid Tumors: Primary Results From the DESTINY-PanTumor02 Phase II Trial
10.1200/jco.2023.41.17_suppl.lba3000 · doi-reference
Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study
10.1016/s1470-2045(23)00275-9 · doi-reference
Adagrasib in Advanced Solid Tumors Harboring a KRAS(G12C) Mutation
10.1200/jco.23.00434 · doi-reference
Dostarlimab: A Review
10.3390/biom12081031 · doi-reference
Management of toxicities from immunotherapy: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up
10.1016/j.annonc.2022.10.001 · doi-reference
Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: ASCO Guideline Update
10.1200/jco.21.01440 · doi-reference
Comparison of microsatellite instability detection by immunohistochemistry and molecular techniques in colorectal and endometrial cancer
10.1038/s41598-021-91974-x · doi-reference
The FDA approval of pembrolizumab for adult and pediatric patients with tumor mutational burden (TMB) >/=10: a decision centered on empowering patients and their physicians
10.1016/j.annonc.2020.07.002 · doi-reference
Tumor mutation burden: from comprehensive mutational screening to the clinic
10.1186/s12935-019-0929-4 · doi-reference
A scoping review and meta-analysis on the prevalence of pan-tumour biomarkers (dMMR, MSI, high TMB) in different solid tumours
10.1038/s41598-022-23319-1 · doi-reference
Microsatellite instability: a review of what the oncologist should know
10.1186/s12935-019-1091-8 · doi-reference
Tumor Mutation Burden and Cancer Treatment
10.1001/jamaoncol.2020.6371 · doi-reference
Pembrolizumab (Keytruda)
10.1080/21645515.2016.1199310 · doi-reference
Larotrectinib: First Global Approval
10.1007/s40265-018-1044-x · doi-reference
Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials
10.1016/s1470-2045(19)30856-3 · doi-reference
Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials
10.1016/s1470-2045(19)30691-6 · doi-reference
NTRK fusions in solid tumours: what every pathologist needs to know
10.1016/j.pathol.2023.05.002 · doi-reference
NTRK gene fusions as novel targets of cancer therapy across multiple tumour types
10.1136/esmoopen-2015-000023 · doi-reference
A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma
10.1038/ng0298-184 · doi-reference
NTRK fusion-positive cancers and TRK inhibitor therapy
10.1038/s41571-018-0113-0 · doi-reference
Targeting TRK family proteins in cancer
10.1016/j.pharmthera.2017.02.006 · doi-reference
Strategies for Mitigating Adverse Events Related to Selective RET Inhibitors in Patients with RET-altered Cancers
10.1016/j.xcrm.2023.101332 · doi-reference
Efficacy of selpercatinib in RET-altered thyroid cancers
10.1056/nejmoa2005651 · doi-reference
Efficacy of Selpercatinib in RET Fusion-Positive Non-Small-Cell Lung Cancer
10.1056/nejmoa2005653 · doi-reference
Tumour-agnostic efficacy and safety of selpercatinib in patients with RET fusion-positive solid tumours other than lung or thyroid tumours (LIBRETTO-001): a phase 1/2, open-label, basket trial
10.1016/s1470-2045(22)00541-1 · doi-reference
Precision oncology with selective RET inhibitor selpercatinib in RET-rearranged cancers
10.1177/17588359231177015 · doi-reference