Mechanism of Buyang Huanwu Decoction in regulating arachidonic acid metabolism to mediate microglial polarization and alleviate cerebral ischemic injury

Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release

10.1152/physrev.00026.2013 · doi-reference

Associations between polyunsaturated fatty acid concentrations and Parkinson's disease: A two-sample Mendelian randomization study

10.3389/fnagi.2023.1123239 · doi-reference

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10.1016/j.ctim.2022.102860 · doi-reference

Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells

10.1016/j.molimm.2019.09.020 · doi-reference

The Role of Arachidonic Acid Metabolism in Myocardial Ischemia-Reperfusion Injury

10.1007/s12013-020-00928-z · doi-reference

Interleukin-11 treatment protected against cerebral ischemia/reperfusion injury

10.1016/j.biopha.2019.108816 · doi-reference

Reactive Oxygen Species (ROS)-Based Nanomedicine

10.1021/acs.chemrev.8b00626 · doi-reference

The Immunomodulatory and Anti-Inflammatory Role of Polyphenols

10.3390/nu10111618 · doi-reference

Efficient Strategies for Microglia Replacement in the Central Nervous System

10.1016/j.celrep.2020.108041 · doi-reference

Annexin A1 protects against cerebral ischemia-reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway

10.1186/s12974-021-02174-3 · doi-reference

The involvement and possible targeting of cardiolipins degradation and disturbed linoleic acid metabolism in cardiac atrophy under cancer cachexia

10.1016/j.ejphar.2024.177108 · doi-reference

Arachidonic Acid Metabolism and Kidney Inflammation

10.3390/ijms20153683 · doi-reference

Glycerophospholipid and Sphingosine- 1-phosphate Metabolism in Cardiovascular Disease: Mechanisms and Therapeutic Potential

10.1007/s12265-025-10620-3 · doi-reference

Microglial metabolic disturbances and neuroinflammation in cerebral infarction

10.1016/j.jphs.2020.11.007 · doi-reference

Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction

10.3389/fncel.2021.661838 · doi-reference

Lipid metabolism in microglia: Emerging mechanisms and therapeutic opportunities for neurodegenerative diseases

10.3892/ijmm.2025.5580 · doi-reference

Neuroimmune mechanisms and therapies mediating post-ischaemic brain injury and repair

10.1038/s41583-023-00690-0 · doi-reference

The phospholipase A2 superfamily and its group numbering system

10.1016/j.bbalip.2006.07.011 · doi-reference

Glycerophospholipid dysregulation after traumatic brain injury

10.1016/j.neuint.2024.105701 · doi-reference

Inflammation and neural repair after ischemic brain injury

10.1016/j.neuint.2018.10.013 · doi-reference

Astrocyte Activation in Neurovascular Damage and Repair Following Ischaemic Stroke

10.3390/ijms22084280 · doi-reference

Astragaloside's Role in Microglial Neuroinflammation: A Multi-Method Study Combining Experimental and Computational Analyses

10.1007/s11064-025-04459-y · doi-reference

Genome-wide association analysis of plasma lipidome identifies 495 genetic associations

10.1038/s41467-023-42532-8 · doi-reference

Updating Phospholipase A2 Biology

10.3390/biom10101457 · doi-reference

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10.1016/j.jep.2024.118636 · doi-reference

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10.1016/j.intimp.2022.109480 · doi-reference

Metabolomics reveals that Da Chuanxiong Formula ameliorates cerebral ischemia/reperfusion injury via regulating membrane phospholipid homeostasis

10.1016/j.brainresbull.2025.111605 · doi-reference

Reversible middle cerebral artery occlusion without craniectomy in rats

10.1161/01.str.20.1.84 · doi-reference

Artificial mesenchymal stem cell extracellular vesicles enhanced ischemic stroke treatment through targeted remodeling brain microvascular endothelial cells

10.1016/j.apsb.2025.06.009 · doi-reference

Quercetin improves cerebral ischemia/reperfusion injury by promoting microglia/macrophages M2 polarization via regulating PI3K/Akt/NF-κB signaling pathway

10.1016/j.biopha.2023.115653 · doi-reference

MFSD2A: a molecular nexus linking blood-brain barrier, lipid metabolism, and ischemia-reperfusion injury

10.1186/s11658-025-00828-1 · doi-reference

Transcriptome Analysis Reveals That NEFA and β-Hydroxybutyrate Induce Oxidative Stress and Inflammatory Response in Bovine Mammary Epithelial Cells

10.3390/metabo12111060 · doi-reference

Single-Atom Nanocatalytic Therapy for Suppression of Neuroinflammation by Inducing Autophagy of Abnormal Mitochondria

10.1021/acsnano.2c12614 · doi-reference

β-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia

10.1186/s12974-015-0355-z · doi-reference

Characterization of SPTLC2 as a key driver promoting microglial activation and energy metabolism reprogramming after ischemic stroke through bulk and single-cell analyses combined with experimental validation

10.1007/s10565-025-10085-9 · doi-reference

Intravenous thrombolysis andmechanical thrombectomy in acute stroke patients on direct oral anticoagulants

10.1007/s00415-024-12832-0 · doi-reference

SOAT1 dysregulation in astrocytes drives Blood-Brain barrier dysfunction and neuroinflammation in Alzheimer's disease

10.1016/j.bbi.2025.04.032 · doi-reference

NFKBIZ mediates neuroprotection and maintains blood-brain barrier integrity in cerebral ischemia/reperfusion via STAT3-regulated Nrf2/ARE signaling

10.1016/j.expneurol.2026.115638 · doi-reference

USP14 inhibition promotes recovery by protecting BBB integrity and attenuating neuroinflammation in MCAO mice

10.1111/cns.14292 · doi-reference

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption

10.1093/ije/dyx102 · doi-reference