Phase I Study of SYNB1891, an engineered E. coli nissle strain expressing STING agonist, with and without atezolizumab in advanced malignancies
10.1158/1078-0432.ccr-23-0118 · doi-reference
An engineered bacterial therapeutic lowers urinary oxalate in preclinical models and in silico simulations of enteric hyperoxaluria
10.15252/msb.202110539 · doi-reference
Activity of SYNB1353, an investigational methionine-consuming synthetic biotic medicine, in an acute nonhuman primate model of homocystinuria
10.1016/j.ymgme.2022.01.075 · doi-reference
An engineered E. coli Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans
10.1126/scitranslmed.aau7975 · doi-reference
Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism
10.1038/s41467-022-31334-z · doi-reference
Probiotic strains detect and suppress cholera in mice
10.1126/scitranslmed.aao2586 · doi-reference
Reprogramming probiotic Lactobacillus reuteri as a biosensor for Staphylococcus aureus derived AIP-I detection
10.1021/acssynbio.8b00063 · doi-reference
Minimal logic gates for probiotic Escherichia coli Nissle 1917 sensing and treatment of dual-bacteria intestinal infection
10.1080/19490976.2025.2530156 · doi-reference
Engineered probiotic Lactobacillus plantarum WCSF I for monitoring and treatment of Staphylococcus aureus infection
10.1128/spectrum.01829-23 · doi-reference
Bioengineered Escherichia coli Nissle 1917 for tumour-targeting therapy
10.1111/1751-7915.13523 · doi-reference
Developing a new class of engineered live bacterial therapeutics to treat human diseases
10.1038/s41467-020-15508-1 · doi-reference
Global analysis of clinical trials with probiotics
10.1016/j.heliyon.2020.e04467 · doi-reference
Probiotics: Growth-Promoting factors produced by microorganisms
10.1126/science.147.3659.747 · doi-reference
Wearable biosensors for healthcare monitoring
10.1038/s41587-019-0045-y · doi-reference
Recent developments in wearable biosensors for healthcare and biomedical applications
10.1016/j.trac.2023.117510 · doi-reference
Wearable materials with embedded synthetic biology sensors for biomolecule detection
10.1038/s41587-021-00950-3 · doi-reference
Epidermal microfluidic electrochemical detection system: enhanced sweat sampling and metabolite detection
10.1021/acssensors.7b00729 · doi-reference
Wearable/disposable sweat-based glucose monitoring device with multistage transdermal drug delivery module
10.1126/sciadv.1601314 · doi-reference
Fully integrated microneedle biosensor array for wearable multiplexed fitness biomarkers monitoring
10.1016/j.bios.2024.116697 · doi-reference
Behavior of polymer electrode PEDOT:PSS/Graphene on flexible substrate for wearable biosensor at different loading modes
10.3390/nano14161357 · doi-reference
A graphene-based electrochemical device with thermoresponsive microneedles for diabetes monitoring and therapy
10.1038/nnano.2016.38 · doi-reference
A recombinase-based genetic circuit for heavy metal monitoring
10.3390/bios12020122 · doi-reference
Development of cell-free platform-based toehold switch system for detection of IP-10 mRNA, an indicator for acute kidney allograft rejection diagnosis
10.1016/j.cca.2020.08.034 · doi-reference
SARS-CoV-2 Detection with De Novo-Designed Synthetic Riboregulators
10.1021/acs.analchem.1c00886 · doi-reference
A wireless, CRISPR-Polymer dot electrochemical sensor for the diagnosis of bacterial pneumonia and multi-drug resistance
10.1021/acsami.3c17151 · doi-reference
A glucose meter interface for point-of-care gene circuit-based diagnostics
10.1038/s41467-020-20639-6 · doi-reference
Electrochemical glucose biosensors
10.1021/cr068123a · doi-reference
A versatile active learning workflow for optimization of genetic and metabolic networks
10.1038/s41467-022-31245-z · doi-reference
Engineering an AI-based forward-reverse platform for the design of cross-ribosome binding sites of a transcription factor biosensor
10.1016/j.csbj.2023.04.026 · doi-reference
Programmable cross-ribosome-binding sites to fine-tune the dynamic range of transcription factor-based biosensor
10.1093/nar/gkaa786 · doi-reference
Encoding genetic circuits with DNA barcodes paves the way for machine learning-assisted metabolite biosensor response curve profiling in yeast
10.1021/acssynbio.1c00595 · doi-reference
Engineering synthetic biology sensors with artificial intelligence: from programmable circuits to next-generation biosensing
10.1016/j.biotechadv.2026.108874 · doi-reference
Genetic circuit design automation
10.1126/science.aac7341 · doi-reference
Construction of a genetic toggle switch in Escherichia coli
10.1038/35002131 · doi-reference
Scalable secondary metabolite production in streptomyces using a plug-and-play system
10.1038/s41587-025-02762-1 · doi-reference
Engineering the ultrasensitive visual whole-cell biosensors by evolved MerR and 5′ UTR for detection of ultratrace Mercury
10.1021/acs.est.3c04915 · doi-reference
Pushing the limits of nickel detection to nanomolar range using a set of engineered bioluminescent Escherichia coli
10.1007/s11356-015-5580-6 · doi-reference
Modification of response behavior of zinc sensing HydHG two-component system using a self-activation loop and genomic integration
10.1007/s00449-012-0845-7 · doi-reference
Phosphatase activity tunes two-component system sensor detection threshold
10.1038/s41467-018-03929-y · doi-reference
Development of colorimetric-based whole-cell biosensor for organophosphorus compounds by engineering transcription regulator DmpR
10.1021/acssynbio.6b00061 · doi-reference
