Carbohydrate-based combinatorial libraries

Michael J. Sofia

doi:10.1023/a:1009650424835

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Carbohydrate-based combinatorial libraries

Michael J. Sofia

Molecular Diversity1997doi:10.1023/a:1009650424835

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Abstract

Carbohydrate-based combinatorial libraries are tremendously valuable for studying the role of sugars in biology and for expanding accessible molecular diversity needed in broad-based drug screening programs. This review discusses the issues that are relevant to the successful implementation of comprehensive carbohydrate-based combinatorial library programs. In addition, details of oligosaccharide and glycoconjugate libraries constructed using both solid phase and solution phase strategies are presented.

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Michael J. Sofia#1

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Carbohydrate-based combinatorial libraries

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